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of Hematology 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2017\uff09\u4e0a\uff0c\u516c\u5e03\u4e86\u897f\u8fbe\u672c\u80fa\u8054\u5408\u4f9d\u897f\u7f8e\u5766\u6cbb\u7597\u6fc0\u7d20\u53d7\u4f53\u9633\u6027\u665a\u671f\u4e73\u817a\u764c\u7684\u5148\u5bfc\u6027\u8bd5\u9a8c\u7ed3\u679c\uff0c\u8bc1\u5b9e\u4e86\u8be5\u8054\u5408\u65b9\u6848\u7684\u5b89\u5168\u6027\u548c\u6f5c\u5728\u7684\u7597\u6548\u3002\u76ee\u524d\uff0c\u897f\u8fbe\u672c\u80fa\u8054\u5408\u4f9d\u897f\u7f8e\u5766\u6cbb\u7597\u6fc0\u7d20\u53d7\u4f53\u9633\u6027\u665a\u671f\u4e73\u817a\u764c\u7684\u968f\u673a\u53cc\u76f2\u7684III\u671f\u7814\u7a76\u5df2\u7ecf\u5728\u5168\u56fd20\u591a\u4e2a\u533b\u9662\u5f00\u5c55\u3002\u897f\u8fbe\u672c\u80fa\u7684\u8868\u89c2\u9057\u4f20\u8c03\u63a7\u673a\u5236\uff0c\u5c06\u53ef\u80fd\u9006\u8f6c\u5df2\u7ecf\u5bf9\u5185\u5206\u6ccc\u7597\u6cd5\u4ea7\u751f\u7684\u8010\u836f\uff0c\u589e\u52a0\u5185\u5206\u6ccc\u6cbb\u7597\u7684\u7597\u6548\u548c\u5ef6\u7f13\u75be\u75c5\u8fdb\u5c55\u6216\u590d\u53d1\uff0c\u671f\u671b\u672a\u6765\u9020\u798f\u4e8e\u4e73\u817a\u764c\u60a3\u8005\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u897f\u8fbe\u672c\u80fa\u5728\u4e2d\u56fd\u4e34\u5e8a\u9002\u5e94\u75c7\u7684\u62d3\u5c55\u5305\u62ec\u8840\u6db2\u80bf\u7624\u3001\u5b9e\u4f53\u7624\u548cHIV\u7b49\u591a\u79cd\u75be\u75c5\u4e34\u5e8a\u7814\u7a76\u90fd\u6b63\u5728\u8fdb\u884c\u3002<\/p>\n<p>\u4f5c\u4e3a\u6211\u56fd\u9996\u4e2a\u5168\u7403\u540c\u6b65\u5f00\u53d1\u7684\u539f\u521b\u65b0\u836f\uff0c\u897f\u8fbe\u672c\u80fa\u5b9e\u73b0\u4e86\u6e90\u4e8e\u4e2d\u56fd\u53d1\u73b0\u3001\u5168\u7403\u540c\u6b65\u5f00\u53d1\u7684\u6218\u7565\u76ee\u6807\uff0c\u5df2\u5728\u7f8e\u56fd\u3001\u65e5\u672c\u3001\u4e2d\u56fd\u53f0\u6e7e\u7b49\u5730\u5f00\u5c55\u4e86\u56fd\u9645\u7814\u53d1\u5de5\u4f5c\u3002\u7f8e\u56fd\u5df2\u5b8c\u6210\u2160\u671f\u4e34\u5e8a\u7814\u7a76\u53ca\u8054\u5408PD-1\u7b49\u7684\u9488\u5bf9\u5b9e\u4f53\u7624\u2161 a\u671f\u4e34\u5e8a\u7814\u7a76\uff1b\u65e5\u672c\u2160\u671f\u4e34\u5e8a\u5b8c\u6210\uff0c\u5b8c\u6210PTCL+\u6210\u4ebaT\u7ec6\u80de\u767d\u8840\u75c5\/\u6dcb\u5df4\u7624\uff08ATLL\uff09\u5b64\u513f\u836f\u7533\u8bf7\uff1b\u4e13\u5229\u6388\u6743\u6211\u56fd\u53f0\u6e7e\u5730\u533a\uff0c\u65e5\u524d\u6b63\u5728\u8fdb\u884cPTCL\u4e0a\u5e02\u7533\u8bf7\u5de5\u4f5c\u5e76\u83b7\u53f0\u6e7eTFDA\u6838\u51c6\u8fdb\u5165\u4e73\u764c\u4e34\u5e8a\u4e09\u671f\u8bd5\u9a8c\uff0c\u8fd9\u662f\u897f\u8fbe\u672c\u80fa\u7ee7PTCL\u4e4b\u540e\u5728\u53f0\u5f00\u53d1\u7684\u7b2c\u4e8c\u4e2a\u9002\u5e94\u75c7\u3002<\/p>\n<p><img decoding=\"async\" class=\" \" src=\"http:\/\/mmbiz.qpic.cn\/mmbiz_jpg\/zDialJKvBosTKIuKmRnzeSt1mtiaFRX5ISv2vpHqvgVGMGdibdTe5rY8fdcezMUwFeYSiasM8siaAR98L5LVfl4r3KQ\/640?wx_fmt=jpeg&amp;wxfrom=5&amp;wx_lazy=1\" data-s=\"300,640\" data-type=\"jpeg\" data-src=\"http:\/\/mmbiz.qpic.cn\/mmbiz_jpg\/zDialJKvBosTKIuKmRnzeSt1mtiaFRX5ISv2vpHqvgVGMGdibdTe5rY8fdcezMUwFeYSiasM8siaAR98L5LVfl4r3KQ\/0?wx_fmt=jpeg\" data-ratio=\"0.64609375\" data-w=\"1280\" data-fail=\"0\" \/><\/p>\n<p><strong>\u5173\u4e8e\u897f\u683c\u5217\u4ed6\u94a0<\/strong><\/p>\n<p>\u897f\u683c\u5217\u4ed6\u94a0\u662f\u6211\u56fd\u81ea\u4e3b\u8bbe\u8ba1\u5408\u6210\u3001\u5e76\u5177\u6709\u5168\u65b0\u5316\u5b66\u7ed3\u6784\u548c\u5168\u7403\u77e5\u8bc6\u4ea7\u6743\u4fdd\u62a4\u7684\u5c0f\u5206\u5b50\u5019\u9009\u836f\u7269\uff0c\u5c5e\u6838\u6fc0\u7d20\u53d7\u4f53\u8fc7\u6c27\u5316\u7269\u9176\u4f53\u589e\u6b96\u7269\u53d7\u4f53\uff08Peroxisome Proliferator-activated Receptor\uff0cPPAR\uff09\u7684\u5168\u6fc0\u52a8\u5242\uff08Pan Agonist\uff09\uff0c\u4e3b\u8981\u9488\u5bf9\u80f0\u5c9b\u7d20\u62b5\u6297\u30012\u578b\u7cd6\u5c3f\u75c5\u53ca\u7cd6\u8102\u4ee3\u8c22\u5f02\u5e38\u76f8\u5173\u75be\u75c5\u7684\u6cbb\u7597\u3002<\/p>\n<p>\u53bb\u5e749\u6708\u7684\u300a\u81ea\u7136\u8bc4\u8bba\uff1a\u5185\u5206\u6ccc\u5b66\u300b(Nature Reviews Endocrinology)\u671f\u520a\u4e0a\uff0c\u8be6\u7ec6\u4ecb\u7ecd\u4e86PPAR\u4e0d\u540c\u4e9a\u578b\u5728\u7cd6\u8102\u4ee3\u8c22\u65b9\u9762\u7684\u4e0d\u540c\u4f5c\u7528\u673a\u5236\u548c\u76f8\u5173\u836f\u7269\u57282\u578b\u7cd6\u5c3f\u75c5\u548c\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u7b49\u75be\u75c5\u4e2d\u7684\u4f5c\u7528\u548c\u6cbb\u7597\u6f5c\u529b\uff0c\u4e0d\u540cPPAR\u4e9a\u578b\u7684\u591a\u91cd\u6fc0\u52a8\u5242\u662f\u672a\u6765\u6cbb\u7597\u80a5\u80d6\u76f8\u5173\u7684\u7cd6\u5c3f\u75c5\u3001\u8840\u8102\u5f02\u5e38\u548c\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u7684\u4e00\u79cd\u975e\u5e38\u6709\u524d\u666f\u7684\u6cbb\u7597\u624b\u6bb5\u3002\u5176\u4e2d\u7279\u522b\u6307\u51fa\uff0c\u5728\u4e2d\u56fd\uff0cPPAR\u5168\u6fc0\u52a8\u5242\uff08Pan Agonist\uff09\u897f\u683c\u5217\u4ed6\u94a0\uff0c\u5728\u5df2\u5b8c\u6210\u7684\u2161\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u5bf92\u578b\u7cd6\u5c3f\u75c5\uff08T2DM\uff09\u60a3\u8005\u4e0d\u4ec5\u663e\u793a\u51fa\u8840\u7cd6\u63a7\u5236\u7597\u6548\uff0c\u8fd8\u5177\u6709\u8c03\u8282\u8102\u4ee3\u8c22\u7d0a\u4e71\u7684\u4f5c\u7528\u3002<\/p>\n<p>2016\u5e749\u6708\uff0c\u8be5\u836f\u8fd11300\u540d\u53d7\u8bd5\u8005\u7684\u4e34\u5e8a\u2162\u671f\u8bd5\u9a8c\u6309\u65f6\u5706\u6ee1\u5b8c\u6210\u5165\u7ec4\uff0c\u4e0e\u6b64\u540c\u65f6\uff0c\u5fae\u82af\u751f\u7269\u7684\u5b50\u516c\u53f8\u6210\u90fd\u5fae\u82af\u836f\u4e1a\u6b63\u5728\u6210\u90fd\u9ad8\u65b0\u897f\u533a\u5efa\u8bbe\u521b\u65b0\u836f\u751f\u4ea7\u57fa\u5730\uff0c\u5176\u4e2d\u7528\u4e8e\u897f\u683c\u5217\u4ed6\u94a0\u539f\u6599\u836f\u548c\u5236\u5242\u751f\u4ea7\u7684\u4e24\u4e2a\u8f66\u95f4\u5df2\u5b8c\u6210\u4e3b\u4f53\u5efa\u8bbe\uff0c\u6b63\u5728\u8fdb\u884c\u8bd5\u8fd0\u884c\u51c6\u5907\uff0c\u9884\u8ba1\u4eca\u5e74\u5e74\u5e95\u6295\u5165\u4f7f\u7528\u3002\u968f\u7740\u2162\u671f\u4e34\u5e8a\u8bd5\u9a8c\u548c\u6210\u90fd\u57fa\u5730\u5efa\u8bbe\u7684\u987a\u5229\u5b8c\u6210\uff0c\u897f\u683c\u5217\u4ed6\u94a0\u5c06\u6709\u671b\u6210\u4e3a2\u578b\u7cd6\u5c3f\u75c5\u6cbb\u7597\u9886\u57df\u5177\u6709\u660e\u663e\u4e34\u5e8a\u5dee\u5f02\u5316\u548c\u7597\u6548\u4f18\u52bf\u7684\u539f\u521b\u65b0\u836f\uff0c\u4e3a\u4e2d\u56fd\u7cd6\u5c3f\u75c5\u60a3\u8005\u63d0\u4f9b\u66f4\u591a\u66f4\u597d\u7684\u9009\u62e9\u3002\uff08\u6765\u6e90\uff1a\u4e2d\u534e\u7f51\uff09<\/p>\n<h2 id=\"activity-name\" class=\"rich_media_title\" style=\"text-align: center;\"><span style=\"color: #000080;\">\u4e9a\u76db\u533b\u836f\u539f\u521b\u65b0\u9776\u70b9\u6297\u80bf\u7624\u836f\u7269Bcl-2\/Bcl-XL\u6291\u5236\u5242 APG-1252\u83b7CFDA\u4e34\u5e8a\u6279\u4ef6<\/span><\/h2>\n<p><a href=\"https:\/\/www.sandiegochinesepress.com\/press\/wp-content\/uploads\/2017\/06\/2016120215090500500.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-1050966\" src=\"https:\/\/www.sandiegochinesepress.com\/press\/wp-content\/uploads\/2017\/06\/2016120215090500500.png\" alt=\"\" width=\"497\" height=\"332\" \/><\/a><\/p>\n<p><span class=\"jj1 selectedTd\">\u90ed\u660e\u535a\u58eb\uff08\u4e0a\u56fe\u4e2d\uff09\u4e3a\u4e9a\u76db\u533b\u836f\u516c\u53f8\u5171\u540c\u521b\u59cb\u4eba\uff0c\u56fd\u5bb6\u201c\u5343\u4eba\u8ba1\u5212\u201d\u4e13\u5bb6\uff0c\u4e4b\u524d\u66fe<\/span><span class=\"jj1 selectedTd\">\u5c31\u804c<\/span><span class=\"jj1 selectedTd\">\u4e8e\u7f8e\u56fd\u5723\u5730\u4e9a\u54e5\u8f89\u745e\u5236\u836f\u7b49<\/span><span class=\"jj1 selectedTd\">\u516c\u53f8<\/span><span class=\"jj1 selectedTd\">\u3002\u56fe\u4e3a2016\u5e74\u5728 \u4e2d\u5c71\u4e3e\u884c\u7684\u6d77\u5916\u751f\u547d\u5065\u5eb7\u521b\u65b0\u521b\u4e1a\u5927\u8d5b\u51b3\u8d5b\u4e2d\uff0c\u4f5c\u4e3a10\u4f4d\u8bc4\u59d4\u4e4b\u4e00\u7684\u90ed\u660e\u535a\u58eb\u5728\u8fdb\u884c\u4e13\u5bb6\u63d0\u95ee\u3002<\/span><\/p>\n<p>2017\u5e746\u670826\u65e5\u4e9a\u76db\u533b\u836f\u5ba3\u5e03\uff0c\u7531\u4f01\u4e1a\u81ea\u4e3b\u8bbe\u8ba1\u5f00\u53d1\u7684\u3001\u5177\u6709\u5168\u7403\u77e5\u8bc6\u4ea7\u6743\u7684\u3001\u7279\u5f02\u6027\u8bf1\u5bfc\u7ec6\u80de\u51cb\u4ea1\u7c7b\u6297\u80bf\u76241\u7c7b\u65b0\u836fAPG-1252\u83b7\u5f97\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u603b\u5c40\uff08CFDA\uff09\u7684\u4e34\u5e8a\u6279\u51c6\uff0c\u8be5\u54c1\u79cd\u4e8e2016\u5e7412\u6708\u6b63\u5f0f\u8fdb\u5165CDE\u6280\u672f\u5ba1\u8bc4\u7a0b\u5e8f\uff0c\u4ec5\u7528\u65f6\u4e0d\u52306\u4e2a\u6708\u5c31\u5b8c\u6210\u6240\u6709\u6280\u672f\u5ba1\u8bc4\u5e76\u83b7\u53d6\u4e34\u5e8a\u6279\u4ef6\u3002<\/p>\n<p><img decoding=\"async\" class=\" 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lang=\"EN-US\">Bcl-X<sub>L<\/sub><\/span>\u6765\u6062\u590d\u80bf\u7624\u7ec6\u80de\u7a0b\u5e8f\u6027\u6b7b\u4ea1\u673a\u5236\uff08\u7ec6\u80de\u51cb\u4ea1\uff09\uff0c\u4ece\u800c\u6740\u6b7b\u80bf\u7624\uff0c\u4e34\u5e8a\u4e0a\u62df\u7528\u4e8e\u5c0f\u7ec6\u80de\u80ba\u764c\u7b49\u5b9e\u4f53\u7624\u7684\u6cbb\u7597\u3002\u8be5\u54c1\u79cd\u4e8e2016\u5e74\u5e95\u83b7\u5f97\u7f8e\u56fdFDA\u6279\u51c6\u8fdb\u5165\u4e34\u5e8a\uff0c\u76ee\u524d\u6b63\u5728\u7f8e\u56fd\u5f00\u5c55\u4e34\u5e8aI\u671f\u8bd5\u9a8c\u3002\u5b83\u662f\u9996\u4e2a\u5728\u7f8e\u8fdb\u5165\u4e34\u5e8a\u3001\u5e76\u7531\u4e2d\u56fd\u4f01\u4e1a\u81ea\u4e3b\u5f00\u53d1\u7684\u7684Bcl-2\/<span 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data-role=\"outer\">\n<section class=\"\" data-tools=\"135\u7f16\u8f91\u5668\" data-id=\"87704\" data-color=\"rgb(55, 74, 174)\" data-custom=\"rgb(55, 74, 174)\">\n<section class=\"\">\n<section>\n<section>\n<section>\u5173\u4e8eAPG-1252\uff1a<\/section>\n<\/section>\n<section>\n<section class=\"\" data-style=\"font-size:14px;\">APG-1252\u662f\u4e9a\u76db\u533b\u836f\u57fa\u4e8e\u5408\u7406\u5316\u8bbe\u8ba1\u7b56\u7565\uff0c\u5728\u56fd\u9645\u9886\u5148\u7684\u86cb\u767d-\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\u836f\u7269\u8bbe\u8ba1\u6838\u5fc3\u6280\u672f\u57fa\u7840\u4e0a\uff0c\u81ea\u4e3b\u8bbe\u8ba1\u5f00\u53d1\u7684Bcl-2\/Bcl-X<sub>L<\/sub>\u53cc\u9776\u70b9\u6291\u5236\u5242\u7c7b\u9ad8\u7aef\u9776\u5411\u6297\u80bf\u7624\u836f\u7269\uff0c\u4e34\u5e8a\u62df\u7528\u4e8e\u5c0f\u7ec6\u80de\u80ba\u764c\u7b49\u5b9e\u4f53\u80bf\u7624\u7684\u6cbb\u7597\u3002Bcl-2\u86cb\u767d\u662f\u516c\u8ba4\u7684\u5927\u591a\u6570\u8840\u6db2\u80bf\u7624\u7684\u4e3b\u5bfc\u81f4\u764c\u57fa\u56e0\uff0c\u800cBcl-X<sub>L<\/sub>\u86cb\u767d\u662f\u9488\u5bf9\u5b9e\u4f53\u80bf\u7624\u6cbb\u7597\u7684\u4e00\u4e2a\u65b0\u5174\u9776\u70b9\u3002\u56e0Bcl-X<sub>L<\/sub>\u86cb\u767d\u5728\u8840\u5c0f\u677f\u4e2d\u8868\u8fbe\uff0c\u4ece\u800c\u4f7fBcl-X<sub>L<\/sub>\u9776\u70b9\u836f\u7269\u9762\u4e34\u8840\u5c0f\u677f\u51cf\u5c11\u7684\u6bd2\u6027\u8fd9\u4e00\u526f\u4f5c\u7528\u96be\u9898\u3002APG-1252\u5e94\u7528\u4e86\u72ec\u7279\u7684\u8bbe\u8ba1\u65b9\u6cd5\uff0c\u4f7f\u5176\u8840\u5c0f\u677f\u6bd2\u6027\u4e5f\u8fdc\u4f4e\u4e8e\u540c\u9776\u70b9\u5176\u5b83\u540c\u7c7b\u836f\u7269\uff0c\u540c\u65f6\u5728\u5c0f\u7ec6\u80de\u80ba\u764c\u7b49\u5b9e\u4f53\u7624\u4e2d\u8868\u73b0\u51fa\u826f\u597d\u7684\u6297\u80bf\u7624\u6d3b\u6027\uff0c\u8fd9\u4e00\u4f18\u52bf\u5728\u4e34\u5e8a\u524d\u7814\u7a76\u4e2d\u5f97\u5230\u4e86\u5145\u5206\u7684\u8bc1\u660e\u3002<a href=\"https:\/\/www.sandiegochinesepress.com\/press\/wp-content\/uploads\/2017\/06\/10-1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-large wp-image-1046298\" src=\"https:\/\/www.sandiegochinesepress.com\/press\/wp-content\/uploads\/2017\/06\/10-1-576x306.jpg\" alt=\"\" width=\"474\" height=\"252\" srcset=\"https:\/\/www.sandiegochinesepress.com\/press\/wp-content\/uploads\/2017\/06\/10-1-576x306.jpg 576w, https:\/\/www.sandiegochinesepress.com\/press\/wp-content\/uploads\/2017\/06\/10-1-300x159.jpg 300w, https:\/\/www.sandiegochinesepress.com\/press\/wp-content\/uploads\/2017\/06\/10-1.jpg 640w\" sizes=\"auto, (max-width: 474px) 100vw, 474px\" \/><\/a>\u90ed\u660e<span class=\"st\">\uff08\u5de6\u4e00\uff09<\/span>\u8fd8\u662f<span class=\"st\">\u7f8e\u4e2d\u751f\u7269\u533b\u5b66\u4e0e\u5236\u836f\u4e13\u4e1a\u534f\u4f1a\uff08SABPA\uff09\u521b\u59cb\u4eba\u4e4b\u4e00\uff0c\u9996\u5c4a\u7406\u4e8b\u4f1a\u7406\u4e8b\u957f\u3002\u56fe\u4e3a\u524d\u4e0d\u4e45<\/span><span class=\"st\">\u90ed\u660e<\/span><span class=\"st\">\u53c2\u52a0\u5728<\/span><span class=\"st\">\u5723\u5730\u4e9a\u54e5<\/span><span class=\"st\">SABPA\u4e3e\u884c\u7684<\/span><span class=\"st\">2017\u5e74Bio\u76db\u4f1a\u65f6\u4e0e\u524d\u4efb\u73b0\u4efbSABPA\u9886\u5bfc\u7684\u5408\u5f71\u3002<\/span><img decoding=\"async\" class=\" \" src=\"http:\/\/mmbiz.qpic.cn\/mmbiz_png\/xKGxlGo5klwxj0tXibVGEcHqKzsVZArVhkoBNVqLNquRtbHHCvhNYdM3dwaTdMEcvthwI3ox4qn5atjvb0xwKtg\/640?wx_fmt=png&amp;wxfrom=5&amp;wx_lazy=1\" width=\"100%\" data-ratio=\"0.40825688073394495\" data-src=\"http:\/\/mmbiz.qpic.cn\/mmbiz_png\/xKGxlGo5klwxj0tXibVGEcHqKzsVZArVhkoBNVqLNquRtbHHCvhNYdM3dwaTdMEcvthwI3ox4qn5atjvb0xwKtg\/640?wx_fmt=png\" data-type=\"png\" data-w=\"436\" data-fail=\"0\" \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section data-role=\"outer\">\n<section class=\"\" data-tools=\"135\u7f16\u8f91\u5668\" data-id=\"87704\" data-color=\"rgb(55, 74, 174)\" data-custom=\"rgb(55, 74, 174)\">\n<section class=\"\">\n<section>\n<section>\n<section>\u5173\u4e8e\u4e9a\u76db\u533b\u836f\uff1a<\/section>\n<\/section>\n<section>\n<section class=\"\" data-style=\"font-size:14px;\">\u4e9a\u76db\u533b\u836f\u662f\u4e00\u5bb6\u7acb\u8db3\u4e2d\u56fd\u3001\u9762\u5411\u5168\u7403\u7684\u539f\u521b\u65b0\u836f\u7814\u53d1\u4f01\u4e1a\uff0c\u5728\u80bf\u7624\u3001\u4e59\u809d\u53ca\u4e0e\u8870\u8001\u76f8\u5173\u7684\u75be\u75c5\u6cbb\u7597\u9886\u57df\u5df2\u6210\u529f\u5e03\u5c40\uff0c\u5c24\u5176\u5728\u7ec6\u80de\u51cb\u4ea1\u548c\u81ea\u566c\u53cc\u901a\u9053\u8c03\u63a7\u6297\u80bf\u7624\u836f\u7269\u9886\u57df\u7684\u7814\u53d1\u9886\u5148\u5168\u7403\uff0c\u6240\u6709\u5728\u7814\u9879\u76ee\u5747\u4e3a\u65b0\u5316\u5408\u7269\u7ed3\u6784\u7684\u539f\u521b1\u7c7b\u65b0\u836f\uff0c\u586b\u8865\u56fd\u5185\u7a7a\u767d\uff0c\u5e76\u65e8\u5728\u8fdb\u519b\u56fd\u9645\u9ad8\u7aef\u533b\u836f\u5e02\u573a\u3002\u516c\u53f8\u62e5\u6709\u4e00\u767e\u591a\u9879\u56fd\u9645\u53d1\u660e\u4e13\u5229\uff0c\u5df2\u6210\u529f\u5f00\u53d1\u8fd110\u9879\u539f\u521b\u65b0\u836f\uff0c\u5176\u4e2d6\u9879\u5df2\u5206\u522b\u8fdb\u5165\u5230\u4e2d\u56fd\u3001\u7f8e\u56fd\u53ca\u6fb3\u5927\u5229\u4e9a\u7684I-II\u671f\u4e34\u5e8a\u5f00\u53d1\u9636\u6bb5\u3002\u4ea7\u54c1\u4f5c\u7528\u9776\u70b9\u5305\u62ec\u7ec6\u80de\u51cb\u4ea1\u53ca\u81ea\u566c\u53cc\u901a\u9053\u8c03\u8282\u65b0\u9776\u70b9Bcl-2\u3001IAP\u53caMDM2-p53\uff0c\u540c\u65f6\u8fd8\u5305\u62ec\u4e34\u5e8a\u9a8c\u8bc1\u6210\u719f\u9776\u70b9ALK\u3001Bcr-Abl\u53cac-Met\u7b49\u3002\uff08\u6765\u6e90\uff1a\u4e9a\u76db\u533b\u836f <span class=\"rich_media_meta rich_media_meta_text rich_media_meta_nickname\">\u836f\u65f6\u4ee3\uff09<\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" data-style=\"font-size:14px;\"><\/section>\n<\/section>\n<\/section>\n<p>&nbsp;<\/p>\n<p><strong><a href=\"https:\/\/www.sandiegochinesepress.com\/press\/?p=599584\">\u94fe\u63a5\uff1a2017\u5e74\u7f8e\u5723\u5730\u4e9a\u54e5\u751f\u836f\u79d1\u6280\u9886\u57df\u6377\u62a5\u9891\u4f20\uff08\u4e00\uff09<\/a><\/strong><br \/>\n<strong> <a href=\"https:\/\/www.sandiegochinesepress.com\/press\/?p=663374\">\u94fe\u63a5\uff1a2017\u5e74\u7f8e\u5723\u5730\u4e9a\u54e5\u751f\u836f\u79d1\u6280\u9886\u57df\u6377\u62a5\u9891\u4f20\uff08\u4e8c\uff09<\/a><\/strong><br \/>\n<strong> <a href=\"https:\/\/www.sandiegochinesepress.com\/press\/?p=689149\">\u94fe\u63a5\uff1a2017\u5e74\u7f8e\u5723\u5730\u4e9a\u54e5\u751f\u836f\u79d1\u6280\u9886\u57df\u6377\u62a5\u9891\u4f20\uff08\u4e09\uff09<\/a><\/strong><br \/>\n<strong> <a 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