{"id":1059901,"date":"2017-06-29T15:03:41","date_gmt":"2017-06-29T22:03:41","guid":{"rendered":"http:\/\/www.sandiegochinesepress.com\/press\/?p=1059901"},"modified":"2017-06-29T20:31:32","modified_gmt":"2017-06-30T03:31:32","slug":"2017%e5%b9%b4%e7%be%8e%e5%9c%a3%e5%9c%b0%e4%ba%9a%e5%93%a5%e7%94%9f%e8%8d%af%e7%a7%91%e6%8a%80%e9%a2%86%e5%9f%9f%e6%8d%b7%e6%8a%a5%e9%a2%91%e4%bc%a0%ef%bc%88%e4%b8%83%ef%bc%89-sabpa","status":"publish","type":"post","link":"https:\/\/www.sandiegochinesepress.com\/press\/2017%e5%b9%b4%e7%be%8e%e5%9c%a3%e5%9c%b0%e4%ba%9a%e5%93%a5%e7%94%9f%e8%8d%af%e7%a7%91%e6%8a%80%e9%a2%86%e5%9f%9f%e6%8d%b7%e6%8a%a5%e9%a2%91%e4%bc%a0%ef%bc%88%e4%b8%83%ef%bc%89-sabpa\/.html","title":{"rendered":"2017\u5e74\u7f8e\u5723\u5730\u4e9a\u54e5\u751f\u836f\u79d1\u6280\u9886\u57df\u6377\u62a5\u9891\u4f20\uff08\u4e03\uff09-SABPA"},"content":{"rendered":"

2017\u5e74\u7f8e\u5723\u5730\u4e9a\u54e5\u751f\u836f\u79d1\u6280\u9886\u57df\u6377\u62a5\u9891\u4f20\uff01\u4e24\u5bb6\u5728\u5723\u5730\u4e9a\u54e5\uff0c\u4e14\u5747\u4ee5\u534e\u4eba\u4e3a\u9886\u5bfc\u4e3b\u529b\u548c\u521b\u59cb\u4eba\u7684\u533b\u836f\u516c\u53f8 – TP Therapeutics INC.\u00a0 \u548cVivace Therapeutics \u559c\u83b7\u7855\u679c\uff01<\/p>\n

\u8bf7\u770b\u836f\u660e\u5eb7\u5fb7\u7684\u8be6\u7ec6\u62a5\u9053\uff1a<\/p>\n

\u901f\u9012 | \u975e\u5c0f\u7ec6\u80de\u80ba\u817a\u764c\u5728\u7814\u65b0\u836f\u83b7FDA\u5b64\u513f\u836f\u8d44\u683c<\/span><\/h5>\n

\u6628\u5929\uff0cTP Therapeutics\u516c\u53f8\u5ba3\u5e03\u7f8e\u56fdFDA\u5df2\u7ecf\u5411\u5176\u5728\u7814\u4e34\u5e8a\u65b0\u836f\u5316\u5408\u7269TPX-0005\u9881\u53d1\u4e86\u5b64\u513f\u836f\u8d44\u683c<\/strong>\uff0c\u7528\u4e8e\u6cbb\u7597\u643a\u5e26ALK<\/em>\u3001ROS1<\/em>\u6216NTRK<\/em>\u81f4\u764c\u57fa\u56e0\u91cd\u6392\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u817a\u764c<\/strong>\u60a3\u8005\u3002<\/p>\n

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TP Therapeutics\u6210\u7acb\u4e8e2013\u5e7410\u6708\uff0c\u662f\u4e00\u5bb6\u4e34\u5e8a\u9636\u6bb5\uff0c\u4e13\u957f\u4e8e\u5316\u5b66\u7ed3\u6784\u7684\u836f\u7269\u8bbe\u8ba1\u516c\u53f8\u3002TP\u7531\u8f89\u745e\uff08Pfizer\uff09\u516c\u53f8\u65d7\u4e0b\u80bf\u7624\u836f\u7269crizotinib\u7684\u53d1\u660e\u8005\u4e4b\u4e00J. Jean Cui\u535a\u58eb\u521b\u7acb\u3002\u8be5\u516c\u53f8\u56e2\u961f\u4fa7\u91cd\u4e8e\u5df2\u7ecf\u786e\u7acb\u7684\u81f4\u75c5\u57fa\u56e0\u9a71\u52a8\u56e0\u7d20\uff0c\u4e13\u6ce8\u4e8e\u9776\u5411\u6027\u65b0\u578b\u5316\u5b66\u5b9e\u4f53\u7684\u8bbe\u8ba1\u548c\u5f00\u53d1\uff1a\u5305\u62ec\u9ad8\u53d1\u7387\u7684\u4e8c\u7ea7\u8010\u836f\u7a81\u53d8\u3001\u65b0\u786e\u5b9a\u7684\u75be\u75c5\u9a71\u52a8\u9776\u70b9\uff0c\u4ee5\u53ca\u8c03\u8282\u80bf\u7624\u5fae\u73af\u5883\u548c\u80bf\u7624\u514d\u75ab\u7684\u6f5c\u5728\u9776\u6807\u3002<\/p>\n

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\u25b2<\/strong>T<\/strong>P Therapeutics\u521b\u59cb\u4eba\u4e4b\u4e00J. Jean Cui\u535a\u58eb<\/strong>\uff08\u56fe\u7247\u6765\u6e90\uff1aTP Therapeutics\uff09<\/strong><\/p>\n

TPX-0005\u662f\u9488\u5bf9ALK\u3001ROS1\u548cTRK\u5bb6\u65cf\u7684\u6709\u6548\u53e3\u670d\u578b\u751f\u7269\u53ef\u5229\u7528\u5c0f\u5206\u5b50\u6fc0\u9176\u6291\u5236\u5242\u3002\u901a\u8fc7\u9776\u5411ALK\u3001ROS1\u6216TRK\u878d\u5408\u6fc0\u9176\u7684\u4e34\u5e8a\u76ca\u5904\u5df2\u7ecf\u88abcrizotinib\u3001ceritinib\u3001alectinib\u548cbrigatinib\u7b49\u836f\u7269\u663e\u8457\u8bc1\u660e\uff0c\u5b83\u4eec\u5df2\u7ecf\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597ALK+\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\uff1bcrizotinib\u5df2\u7ecf\u83b7\u6279\u7528\u4e8eROS1+\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff1b\u540c\u65f6\uff0clerotrectinib\u548centrectinib\u5904\u4e8e\u9488\u5bf9TRK+\u764c\u75c7\u9002\u5e94\u75c7\u7684\u4e34\u5e8a\u7814\u7a76\u9636\u6bb5\u3002\u7136\u800c\uff0c\u80bf\u7624\u7684\u83b7\u5f97\u6027\u8010\u836f\u6027\u5f80\u5f80\u4f1a\u9650\u5236\u8fd9\u4e9b\u7597\u6cd5\u7684\u6548\u679c\u3002<\/p>\n

\u8fd9\u4e9b\u83b7\u5f97\u6027\u7a81\u53d8\u5305\u62ec\u4e86ALK G1202R\u3001ROS1 G2032R\u3001TRKA G595R\u548cTRKC G623R\uff0c\u5b83\u4eec\u662f\u76ee\u524dALK\u3001ROS1\u548cTRK\u6291\u5236\u5242\u5e38\u89c1\u7684\u4e34\u5e8a\u8010\u836f\u6027\u7684\u6839\u6e90\u3002\u4f5c\u4e3a\u4e00\u79cd\u9488\u5bf9\u91ce\u751f\u548c\u7a81\u53d8\u578bALK\u3001ROS1\u548cTRK\u5bb6\u65cf\u6fc0\u9176\u7684\u5f3a\u529b\u6291\u5236\u5242\uff0cTPX-0005\u7279\u522b\u5177\u6709\u89e3\u51b3\u4e34\u5e8a\u4e0a\u91cd\u8981\u7684\u5355\u4e2a\u7a81\u53d8\u548c\u590d\u5408\u7a81\u53d8\u7684\u6f5c\u529b\u3002\u8be5\u5728\u7814\u5c0f\u5206\u5b50\u5c06\u4e3a\u4e34\u5e8a\u6cbb\u7597\u63d0\u4f9b\u65b0\u7684\u673a\u4f1a\uff0c\u6291\u5236ALK\u3001ROS1\u6216TRK\u5bb6\u65cf\u5728\u5b9e\u4f53\u6076\u6027\u80bf\u7624\u4e2d\u7684\u5f02\u5e38\u4fe1\u53f7\u4f20\u5bfc\uff0c\u514b\u670d\u96be\u6cbb\u6027\u60a3\u8005\u7684\u591a\u91cd\u8010\u836f\u6027\u673a\u5236<\/strong>\u3002<\/p>\n

TPX-0005\u76ee\u524d\u6b63\u5904\u4e8e1\/2\u671f\u3001\u5f00\u653e\u6807\u7b7e\u3001\u591a\u4e2d\u5fc3\u4e34\u5e8a\u7814\u7a76\u8bd5\u9a8c\u9636\u6bb5\uff0c\u5728ALK\u3001ROS1\u6216NTRK1-3\u91cd\u6392\u7a81\u53d8\u665a\u671f\u5b9e\u4f53\u7624\u60a3\u8005\u7fa4\u4f53\u4e2d\u8bc4\u4f30\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u3001\u836f\u4ee3\u52a8\u529b\u5b66\u548c\u6297\u80bf\u7624\u6d3b\u6027<\/strong>\u3002<\/p>\n

\u53c2\u8003\u8d44\u6599\uff1a<\/p>\n

[1] TP Therapeutics Announces FDA Orphan Drug Designation Granted To TPX-0005 For Treatment Of Non-Small Cell Lung Adenocarcinomas Harboring ALK, ROS1, Or NTRK Oncogenic Rearrangements<\/p>\n

[2] TP Therapeutics\u5b98\u65b9\u7f51\u7ad9<\/p>\n

\u795d\u8d3a\uff01\u878d\u8d444000\u4e07\u7f8e\u5143\uff0cVivace\u4eca\u65e5\u95ea\u4eae\u767b\u573a<\/span><\/h5>\n

\u65b0\u9510\u540d\u79f0\uff1a<\/strong>Vivace Therapeutics<\/p>\n

\u516c\u53f8\u5750\u6807\uff1a<\/strong>\u52a0\u5229\u798f\u5c3c\u4e9a\u5dde\uff0cSan Mateo\u5e02<\/p>\n

\u5b98\u65b9\u7f51\u7ad9\uff1a<\/strong>http:\/\/vivacetherapeutics.com\/<\/p>\n

\u878d\u8d44\u60c5\u51b5\uff1a<\/strong>A\u8f6e\u3001B\u8f6e\u5171\u878d\u8d444000\u4e07\u7f8e\u5143<\/p>\n

\u7ba1\u7406\u56e2\u961f\uff1a<\/strong>\u4e54\u723d\uff08Sofie Qiao\uff09\u535a\u58eb\u4e3a\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98\uff1bLeonard Post\u535a\u58eb\u4e3a\u9996\u5e2d\u79d1\u5b66\u5b98\uff1b\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\uff08UCSD\uff09\u7ba1\u5764\u826f\u6559\u6388\u3001\u52a0\u5dde\u5927\u5b66\u65e7\u91d1\u5c71\u5206\u6821\uff08UCSF\uff09\u5218\u658c\u6559\u6388\u3001\u52a0\u5dde\u5927\u5b66\u65e7\u91d1\u5c71\u5206\u6821\u4e01\u80dc\u6559\u6388\u4e3a\u5171\u540c\u79d1\u5b66\u521b\u59cb\u4eba<\/p>\n

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\u4eca\u65e5\uff0c\u4e00\u5bb6\u540d\u4e3aVivace Therapeutics\u7684\u521d\u521b\u516c\u53f8\u752b\u4e00\u767b\u573a\uff0c\u5c31\u8fc5\u901f\u6210\u4e3a\u4e86\u4e1a\u5185\u5173\u6ce8\u7684\u7126\u70b9\u3002<\/strong>\u5305\u62ec\u300a\u534e\u5c14\u8857\u65e5\u62a5\u300b\u5728\u5185\uff0c\u591a\u5bb6\u77e5\u540d\u5a92\u4f53\u7eb7\u7eb7\u5bf9\u8fd9\u5bb6\u751f\u7269\u533b\u836f\u65b0\u9510\u8fdb\u884c\u62a5\u9053\uff0c\u5e76\u770b\u597d\u5b83\u80fd\u5728\u4e2d\u7f8e\u4e24\u5730\u5353\u8d8a\u7684\u79d1\u5b66\u3001\u6295\u8d44\u3001\u7ba1\u7406\u56e2\u961f\u7684\u9886\u5bfc\u4e0b\uff0c\u5c06\u521b\u65b0\u751f\u7269\u6280\u672f\u8f6c\u5316\u4e3a\u5168\u65b0\u6297\u764c\u7597\u6cd5\u3002<\/p>\n

\u63a2\u7d22\u5168\u65b0\u6297\u764c\u901a\u8def<\/strong><\/p>\n

Vivace\u4e13\u6ce8\u7684\u65b9\u5411\u662fHippo-YAP\u4fe1\u53f7\u901a\u8def<\/strong>\u3002\u5728\u6b63\u5e38\u60c5\u51b5\u4e0b\uff0c\u8fd9\u6761\u901a\u8def\u80fd\u591f\u63a7\u5236\u7ec4\u7ec7\u518d\u751f\uff0c\u4ee5\u53ca\u5668\u5b98\u7684\u5c3a\u5bf8\u548c\u5f62\u72b6\u3002\u4e5f\u6b63\u662f\u7531\u4e8e\u8fd9\u6761\u901a\u8def\u7684\u91cd\u8981\u6027\uff0c\u4e00\u65e6\u5b83\u51fa\u73b0\u4e86\u5f02\u5e38\u7a81\u53d8\uff0c\u5c31\u6709\u53ef\u80fd\u5bfc\u81f4\u80c3\u764c\u3001\u7ed3\u80a0\u764c\u3001\u5bab\u9888\u764c\u3001\u5375\u5de2\u764c\u3001\u4e73\u817a\u764c\u7b49\u4e00\u7cfb\u5217\u764c\u75c7\u3002\u6b64\u5916\uff0c\u8fd9\u6761\u901a\u8def\u4e2d\u7684YAP\u86cb\u767d\u6d3b\u6027\u4e5f\u548c\u9776\u5411\u7597\u6cd5\u7684\u8010\u836f\u6027\uff0c\u4ee5\u53ca\u764c\u75c7\u7684\u590d\u53d1\u6709\u5173\u3002\u7531\u6b64\u53ef\u89c1\uff0c\u5018\u82e5\u80fd\u5bf9\u8fd9\u6761\u901a\u8def\u8fdb\u884c\u6709\u6548\u7684\u8c03\u63a7\uff0c\u6211\u4eec\u4e0d\u4f46\u6709\u671b\u63d0\u9ad8\u6297\u764c\u7597\u6cd5\u7684\u6548\u679c\uff0c\u964d\u4f4e\u764c\u75c7\u590d\u53d1\u7684\u98ce\u9669\uff0c\u66f4\u6709\u53ef\u80fd\u4e3a\u591a\u79cd\u764c\u75c7\u63d0\u4f9b\u6f5c\u5728\u6cbb\u7597\u65b9\u6848\u3002<\/strong><\/p>\n

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Vivace\u7684\u5171\u540c\u79d1\u5b66\u521b\u59cb\u4eba\u3001\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u7ba1\u5764\u826f\u6559\u6388\uff08\u56fe\u7247\u6765\u6e90\uff1aUCSD\uff09<\/strong><\/p>\n

\u8fd1\u671f\uff0c\u4eba\u7c7b\u5bf9Hippo-YAP\u4fe1\u53f7\u901a\u8def\u53c8\u6709\u4e86\u65b0\u7684\u8ba4\u8bc6\u548c\u7406\u89e3\u3002Vivace\u7684\u5171\u540c\u79d1\u5b66\u521b\u59cb\u4eba\u3001\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u7ba1\u5764\u826f\u6559\u6388\u7684\u7814\u7a76\u56e2\u961f\u53bb\u5e74\u5728\u751f\u7269\u5b66\u9886\u57df\u9876\u5c16\u5b66\u672f\u671f\u520a\u300a\u7ec6\u80de\u300b\u4e0a\u53d1\u8868\u7814\u7a76\u8bba\u6587\uff0c\u53d1\u73b0\u8fd9\u6761\u901a\u8def\u91cc\u7684LATS1\/2\u6fc0\u9176\u80fd\u6291\u5236\u7528\u4e8e\u6297\u80bf\u7624\u7684\u514d\u75ab\u80fd\u529b\u3002\u8fdb\u4e00\u6b65\u7684\u7814\u7a76\u53d1\u73b0\uff0c\u5f53\u6572\u9664LATS1\/2\u6fc0\u9176\u540e\uff0c\u80bf\u7624\u7684\u514d\u75ab\u539f\u6027\u4f1a\u5f97\u5230\u52a0\u5f3a\uff0c\u4ece\u800c\u8ba9\u514d\u75ab\u7cfb\u7edf\u66f4\u597d\u5730\u8bc6\u522b\u548c\u6740\u4f24\u80bf\u7624\u3002<\/strong>\u8fd9\u4e00\u53d1\u73b0\uff0c\u4e5f\u6709\u671b\u8ba9LATS1\/2\u6fc0\u9176\u6210\u4e3a\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u7684\u65b0\u9776\u70b9\u3002\u8fd9\u6b63\u662fVivace\u63a2\u7d22\u7684\u65b9\u5411\u3002<\/p>\n

<\/p>\n

LATS1\/2\u6709\u671b\u6210\u4e3a\u80bf\u7624\u514d\u75ab\u7597\u6cd5\u65b0\u9776\u70b9\uff08\u56fe\u7247\u6765\u6e90\uff1a\u300a\u7ec6\u80de\u300b\uff09<\/strong><\/p>\n

\u5353\u8d8a\u56e2\u961f\u5e26\u6765\u65e0\u9650\u6f5c\u529b<\/strong><\/p>\n

Vivace\u7684\u5353\u8d8a\u56e2\u961f\u8ba9\u4eba\u770b\u5230\u4e86\u5b83\u7684\u65e0\u9650\u6f5c\u529b\u3002\u5728\u7ba1\u5764\u826f\u6559\u6388\u4e4b\u5916\uff0c\u52a0\u5dde\u5927\u5b66\u65e7\u91d1\u5c71\u5206\u6821\u7684\u5218\u658c\u6559\u6388\u4e0e\u4e01\u80dc\u6559\u6388\u4e5f\u662f\u8be5\u516c\u53f8\u7684\u5171\u540c\u79d1\u5b66\u521b\u59cb\u4eba\u3002\u5218\u658c\u6559\u6388\u5728\u53cc\u7279\u5f02\u6027\u6297\u4f53\u7684\u8bbe\u8ba1\u4e0e\u7814\u53d1\u4e0a\u53d6\u5f97\u4e86\u5168\u7403\u77a9\u76ee\u7684\u6210\u7ee9<\/strong>\uff0c\u4ed6\u7684\u53cc\u7279\u5f02\u6027\u6297\u4f53\u6280\u672f\u5e73\u53f0\u53ef\u52a9\u529bVivace\u7814\u53d1\u51fa\u5177\u6709\u9ad8\u5ea6\u7279\u5f02\u6027\u7684\u514d\u75ab\u7597\u6cd5\uff1b\u4e01\u80dc\u6559\u6388\u662f\u5168\u7403\u7814\u7a76\u5e72\u7ec6\u80de\u548c\u518d\u751f\u533b\u5b66\u7684\u9886\u519b\u4eba\u7269\u4e4b\u4e00\uff0c\u4e5f\u662f\u6e05\u534e\u5927\u5b66\u836f\u5b66\u9662\u7684\u9996\u4efb\u9662\u957f<\/strong>\u3002\u4ed6\u7684\u5de5\u4f5c\u6709\u671b\u5e2e\u52a9Vivace\u5bfb\u627eHippo-YAP\u4fe1\u53f7\u901a\u8def\u5728\u5176\u4ed6\u75be\u75c5\u4e2d\u7684\u6f5c\u5728\u5e94\u7528\u3002<\/p>\n

Vivace\u7684\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98\u4e54\u723d\u535a\u58eb\u5728\u4e1a\u754c\u6709\u7740\u4e30\u5bcc\u7ecf\u9a8c<\/strong>\u30022006\u5e74\uff0c\u5979\u66fe\u5171\u540c\u521b\u7acb\u4e86LEAD Therapeutics\uff0c\u5e76\u4e0e\u73b0\u4efbVivace\u7684\u9996\u5e2d\u79d1\u5b66\u5b98Leonard Post\u535a\u58eb<\/strong>\u9886\u5bfc\u7684\u79d1\u7814\u56e2\u961f\u4e00\u9053\uff0c\u4e3a\u4e1a\u754c\u5e26\u6765\u4e86\u8457\u540d\u7684PARP\u6291\u5236\u5242talazoparib\u3002\u5982\u4eca\uff0c\u8fd9\u652f\u6210\u529f\u56e2\u961f\u5c06\u5728Vivace\u518d\u5ea6\u542f\u822a\uff0c\u671f\u5f85\u4e66\u5199\u65b0\u7684\u8f89\u714c\u3002<\/p>\n

<\/p>\n

Vivace\u7684\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98\u4e54\u723d\u535a\u58eb\uff08\u56fe\u7247\u6765\u6e90\uff1a\u6bd3\u627f\u8d44\u672c\uff09<\/strong><\/p>\n

\u201c\u81ea\u4ece\u516c\u53f8\u6210\u7acb\u4ee5\u6765\uff0c\u6211\u4eec\u5c31\u4e00\u76f4\u4e13\u6ce8\u4e8e\u6c47\u96c6\u4e2d\u7f8e\u4e24\u5730\u7684\u9876\u5c16\u4e13\u5bb6\uff0c\u5c06\u521b\u65b0\u751f\u7269\u6280\u672f\u8f6c\u5316\u4e3a\u540c\u7c7b\u9996\u4e2a\uff08first-in-class\uff09\u7684\u80bf\u7624\u7597\u6cd5\u3002\u6211\u5f88\u9ad8\u5174\u80fd\u4e0e\u6211\u4eec\u7684\u79d1\u5b66\u5171\u540c\u521b\u59cb\u4eba\u7ec4\u6210\u56e2\u961f\uff0c\u201d\u4e54\u723d\u535a\u58eb\u8bf4\uff1a\u201c\u4e5f\u5f88\u9ad8\u5174\u80fd\u4e0eLeonard Post\u535a\u58eb\u7ee7LEAD Therapeutics\u540e\uff0c\u5728\u53e6\u4e00\u5bb6\u6297\u80bf\u7624\u516c\u53f8\u8fdb\u884c\u5408\u4f5c\u3002\u201d<\/p>\n

\u77e5\u540d\u98ce\u6295\u9886\u8854\u6295\u8d44\uff0c\u52a9\u529b\u5b9e\u73b0\u68a6\u60f3<\/strong><\/p>\n

Vivace\u7684\u6f5c\u529b\u4e5f\u5f97\u5230\u4e86\u8bf8\u591a\u77e5\u540d\u98ce\u6295\u7684\u770b\u597d\u30022015\u5e74\uff0c\u6bd3\u627f\u8d44\u672c\u4e0eCanaan Partners\u5171\u540c\u534f\u52a9Vivace\u6210\u7acb\uff0c\u5e76\u5728A\u8f6e\u878d\u8d44\u4e2d\u6295\u5165\u4e861500\u4e07\u7f8e\u5143\u7684\u8d44\u91d1\u3002\u8fd1\u671f\uff0c\u5343\u9aa5\u8d44\u672c\uff08Cenova Capital\uff09\u9886\u6295\u4e86\u989d\u5ea6\u4e3a2500\u4e07\u7f8e\u5143\u7684B\u8f6e\u878d\u8d44\uff0c\u65b0\u6295\u8d44\u65b9\u7ea2\u6749\u8d44\u672c\u4e2d\u56fd\uff08Sequoia Capital China\uff09\u3001\u6bd3\u627f\u8d44\u672c\u3001Canaan Partners\u540c\u6837\u53c2\u4e0e\u4e86\u672c\u8f6e\u878d\u8d44\u3002<\/strong><\/p>\n

<\/p>\n

\u6bd3\u627f\u8d44\u672c\u521b\u59cb\u5408\u4f19\u4eba\u80e1\u6b63\u56fd\u5148\u751f\uff08\u56fe\u7247\u6765\u6e90\uff1a\u6bd3\u627f\u8d44\u672c\uff09<\/strong><\/p>\n

\u201c\u6211\u4eec\u5f88\u9ad8\u5174\u770b\u5230Vivace\u81ea2015\u5e74\u6210\u7acb\u4ee5\u6765\u53d6\u5f97\u7684\u8fdb\u5c55\uff0c\u201d\u6bd3\u627f\u8d44\u672c\u521b\u59cb\u5408\u4f19\u4eba\u80e1\u6b63\u56fd\u5148\u751f\u8bf4\u9053\uff1a\u201c\u6211\u4eec\u4e5f\u5f88\u9ad8\u5174\u770b\u5230\u9886\u5148\u7684\u4e2d\u56fd\u6295\u8d44\u8005\u5343\u9aa5\u8d44\u672c\u548c\u7ea2\u6749\u8d44\u672c\u4e2d\u56fd\u80fd\u591f\u52a0\u5165\u6295\u8d44\u884c\u5217\u3002\u201d<\/p>\n

\u201cVivace\u6709\u8bb8\u591a\u521b\u65b0\u4e14\u6709\u6f5c\u529b\u7684\u4e34\u5e8a\u9879\u76ee\u30021\u671f\u4e34\u5e8a\u91cc\uff0c\u5728\u7ecf\u8fc7\u5206\u5b50\u6807\u5fd7\u7269\u7b5b\u9009\u7684\u60a3\u8005\u4e2d\uff0c\u5b83\u4eec\u6709\u671b\u5c55\u73b0\u6d3b\u6027\uff0c\u8ba9\u6211\u4eec\u80fd\u5728\u65e9\u671f\u8bc4\u4f30\u8fd9\u4e9b\u8f6c\u5316\u7597\u6cd5\uff0c\u201dCanaan Partners\u7684\u666e\u901a\u5408\u4f19\u4eba\uff08General Partner\uff09Tim Shannon\u535a\u58eb\u8bf4\u9053\uff1a\u201c\u901a\u8fc7\u7ed3\u5408\u7f8e\u56fd\u7684\u5546\u4e1a\u4e0e\u79d1\u5b66\u9886\u5bfc\u529b\uff0c\u4ee5\u53ca\u4e2d\u56fd\u7684\u7814\u7a76\u80fd\u529b\uff0cVivace\u80fd\u91c7\u53d6\u6709\u6548\u7684\u521b\u65b0\u624b\u6bb5\uff0c\u8fdb\u884c\u65b0\u836f\u53d1\u73b0\u3002\u201d<\/p>\n

\u8bb8\u591a\u516c\u53f8\u7684\u521b\u59cb\u4eba\u5c06\u7f8e\u597d\u7684\u5bd3\u610f\u7f6e\u4e8e\u516c\u53f8\u7684\u540d\u79f0\u4e4b\u5185\uff0cVivace\u4e5f\u4e0d\u4f8b\u5916\u2014\u2014\u8fd9\u4e2a\u5355\u8bcd\u6765\u6e90\u4e8e\u62c9\u4e01\u8bed\uff0c\u610f\u4e3a\u201c\u957f\u5bff\u201d\u3002<\/strong>\u6211\u4eec\u795d\u613fVivace\u80fd\u5728\u5353\u8d8a\u7684\u79d1\u5b66\u3001\u6295\u8d44\u3001\u7ba1\u7406\u56e2\u961f\u7684\u9886\u5bfc\u4e0b\uff0c\u53d6\u5f97\u51fa\u8272\u7684\u4e34\u5e8a\u6210\u679c\uff0c\u65e9\u65e5\u4e3a\u60a3\u8005\u4eec\u5e26\u6765\u521b\u65b0\u6297\u764c\u7597\u6cd5\uff0c\u5e2e\u52a9\u4ed6\u4eec\u6218\u80dc\u75c5\u9b54\u3002<\/p>\n

\u53c2\u8003\u8d44\u6599\uff1a<\/p>\n

[1] Vivace Therapeutics Comes out of Stealth with $40 Million to Turn Novel Biology into First-in-Class Cancer Therapeutics<\/p>\n

[2] Vivace\u5b98\u65b9\u7f51\u7ad9<\/p>\n

\uff08\u6765\u6e90\uff1a\u836f\u660e\u5eb7\u5fb7\uff09<\/p>\n

\u94fe\u63a5\uff1a2017\u5e74\u7f8e\u5723\u5730\u4e9a\u54e5\u751f\u836f\u79d1\u6280\u9886\u57df\u6377\u62a5\u9891\u4f20\uff08\u4e00\uff09<\/a><\/strong>
\n \u94fe\u63a5\uff1a2017\u5e74\u7f8e\u5723\u5730\u4e9a\u54e5\u751f\u836f\u79d1\u6280\u9886\u57df\u6377\u62a5\u9891\u4f20\uff08\u4e8c\uff09<\/a><\/strong>
\n \u94fe\u63a5\uff1a2017\u5e74\u7f8e\u5723\u5730\u4e9a\u54e5\u751f\u836f\u79d1\u6280\u9886\u57df\u6377\u62a5\u9891\u4f20\uff08\u4e09\uff09<\/a><\/strong>
\n \u94fe\u63a5\uff1a2017\u5e74\u7f8e\u5723\u5730\u4e9a\u54e5\u751f\u836f\u79d1\u6280\u9886\u57df\u6377\u62a5\u9891\u4f20\uff08\u56db\uff09<\/a><\/strong>
\n \u94fe\u63a5\uff1a2017\u5e74\u7f8e\u5723\u5730\u4e9a\u54e5\u751f\u836f\u79d1\u6280\u9886\u57df\u6377\u62a5\u9891\u4f20\uff08\u4e94\uff09<\/a><\/strong>
\n \u94fe\u63a5\uff1a2017\u5e74\u7f8e\u5723\u5730\u4e9a\u54e5\u751f\u836f\u79d1\u6280\u9886\u57df\u6377\u62a5\u9891\u4f20\uff08\u516d\uff09<\/a><\/strong><\/p>\n

\"\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

2017\u5e74\u7f8e\u5723\u5730\u4e9a\u54e5\u751f\u836f\u79d1\u6280\u9886\u57df\u6377\u62a5\u9891\u4f20\uff01\u4e24\u5bb6\u5728\u5723\u5730\u4e9a\u54e5\uff0c\u4e14\u5747\u4ee5\u534e\u4eba\u4e3a\u9886\u5bfc\u4e3b\u529b\u548c\u521b\u59cb\u4eba\u7684\u533b\u836f\u516c\u53f8 – TP Therapeutics INC. \u548cVivace Therapeutics \u559c\u83b7\u7855\u679c\uff01….<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-1059901","post","type-post","status-publish","format-standard","hentry","category-local_news"],"_links":{"self":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/1059901","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/comments?post=1059901"}],"version-history":[{"count":0,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/1059901\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/media?parent=1059901"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/categories?post=1059901"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/tags?post=1059901"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}