{"id":1300029,"date":"2018-05-04T15:27:15","date_gmt":"2018-05-04T22:27:15","guid":{"rendered":"http:\/\/www.sandiegochinesepress.com\/press\/?p=1300029"},"modified":"2018-05-04T15:27:15","modified_gmt":"2018-05-04T22:27:15","slug":"%e4%b8%b9%e6%89%ac%e3%80%81%e5%bc%a0%e9%94%8b%e3%80%81%e5%82%85%e5%ab%88%e6%83%a0%e3%80%81%e9%ab%98%e5%8d%8e%e5%81%a5%e3%80%81%e6%96%87%e5%b0%8f%e5%88%9a%e3%80%81%e6%9e%97%e6%b5%b7%e5%b8%86%e5%bd%93","status":"publish","type":"post","link":"https:\/\/www.sandiegochinesepress.com\/press\/%e4%b8%b9%e6%89%ac%e3%80%81%e5%bc%a0%e9%94%8b%e3%80%81%e5%82%85%e5%ab%88%e6%83%a0%e3%80%81%e9%ab%98%e5%8d%8e%e5%81%a5%e3%80%81%e6%96%87%e5%b0%8f%e5%88%9a%e3%80%81%e6%9e%97%e6%b5%b7%e5%b8%86%e5%bd%93\/.html","title":{"rendered":"\u4e39\u626c\u3001\u5f20\u950b\u3001\u5085\u5ac8\u60e0\u3001\u9ad8\u534e\u5065\u3001\u6587\u5c0f\u521a\u3001\u6797\u6d77\u5e06\u5f53\u90092018\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u58eb"},"content":{"rendered":"<div class=\"news\">\n<p>2018\u5e745\u67081\u65e5\uff0c\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u5b98\u7f51\u516c\u5e03\u4e86\u65b0\u5f53\u9009\u9662\u58eb\u540d\u5355\u3002\u56e0\u5728\u539f\u521b\u6027\u7814\u7a76\u65b9\u9762\u7684\u6770\u51fa\u8d21\u732e\u4e0e\u6301\u7eed\u6210\u5c31\uff0c84\u540d\u7f8e\u56fd\u79d1\u5b66\u5bb6\u4ee5\u53ca21\u540d\u5916\u7c4d\u79d1\u5b66\u5bb6\u5f53\u9009\u65b0\u4e00\u5c4a\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u58eb\u3002<\/p>\n<p>\u7f8e\u56fd\u79d1\u5b66\u9662\uff08National Academy of Sciences\uff09\u4e8e1863\u5e74\u7531\u7f8e\u56fd\u524d\u603b\u7edf\u4e9a\u4f2f\u62c9\u7f55\u00b7\u6797\u80af\u5ba3\u5e03\u6210\u7acb\u3002\u76ee\u524d\u5171\u7531\u4e09\u90e8\u5206\u7ec4\u6210\uff1a\u7f8e\u56fd\u56fd\u5bb6\u7814\u7a76\u59d4\u5458\u4f1a\u3001\u7f8e\u56fd\u56fd\u5bb6\u5de5\u7a0b\u9662\u548c\u7f8e\u56fd\u533b\u5b66\u7814\u7a76\u6240\uff0c\u5b83\u4eec\u5206\u522b\u4e8e1916\u5e74\u30011964\u5e74\u4ee5\u53ca1970\u5e74\u6210\u7acb\u3002\u4ece\u8d77\u521d\u768450\u4f4d\u6210\u5458\uff0c\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u73b0\u5728\u5df2\u7ecf\u53d1\u5c55\u81f32250\u540d\u6210\u5458\uff0c\u5176\u4e2d\u6709452\u540d\u6210\u5458\u4e3a\u5916\u7c4d\u9662\u58eb\uff08\u5373\u62e5\u6709\u9664\u7f8e\u56fd\u4ee5\u5916\u56fd\u7c4d\u7684\u5b66\u8005\uff09\uff0c\u5927\u7ea6\u6709200\u4e2a\u9662\u58eb\u83b7\u5f97\u4e86\u8bfa\u8d1d\u5c14\u5956\u3002<\/p>\n<p>\u5728\u5386\u5e74\u5f53\u9009\u7684\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u58eb\u6216\u8005\u5916\u7c4d\u9662\u58eb\u540d\u5355\u4e2d\uff0c\u6709\u5f88\u591a\u534e\u4eba\u5b66\u8005\u7684\u8eab\u5f71\uff0c\u5305\u62ec\u674e\u653f\u9053\u3001\u6768\u632f\u5b81\u3001\u65bd\u4e00\u516c\u3001\u8881\u9686\u5e73\u7b49\u8457\u540d\u79d1\u5b66\u5bb6\u3002\u622a\u81f3\u76ee\u524d\uff0c\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u5728\u804c\u9662\u58eb\u603b\u6570\u8fbe\u52302382\u540d\uff0c\u5916\u7c4d\u9662\u58eb\u4e3a484\u540d\u3002<\/p>\n<p><strong>2018\u5e74\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u58eb\uff08\u534e\u4eba\u5b66\u8005\uff09\uff1a<\/strong><\/p>\n<p>\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821\u6559\u6388\u4e39\u626c\uff08Yang Dan\uff09\uff1b<\/p>\n<p>\u52a0\u5dde\u5927\u5b66\u65e7\u91d1\u5c71\u5206\u6821\u6559\u6388\u5085\u5ac8\u60e0\uff08Ying-Hui Fu\uff09\uff1b<\/p>\n<p>\u5e03\u6717\u5927\u5b66\u6559\u6388\u9ad8\u534e\u5065\uff08Huajian Gao\uff09\uff1b<\/p>\n<p>\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u6559\u6388\u6587\u5c0f\u521a\uff08Xiao-Gang Wen\uff09\uff1b<\/p>\n<p>\u8036\u9c81\u5927\u5b66\u6559\u6388\u6797\u6d77\u5e06\uff08Haifan Lin\uff09\uff1b<\/p>\n<p>\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u6559\u6388\u5f20\u950b\uff08Feng Zhang\uff09\u3002<\/p>\n<p>6\u4f4d\u534e\u4eba\u5b66\u8005\u4e2d\uff0c\u9664\u5085\u5ac8\u60e0\u548c\u5f20\u950b\u5916\uff0c\u5747\u6709\u4e2d\u56fd\u5927\u9646\u9ad8\u6821\u672c\u79d1\u5b66\u5386\u80cc\u666f\u3002\u6b64\u5916\uff0c\u8036\u9c81\u5927\u5b66\u6559\u6388\u6797\u6d77\u5e06\u548c\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u6559\u6388\u5f20\u950b4\u6708\u4efd\u521a\u521a\u62ff\u4e0b\u7f8e\u56fd\u4eba\u6587\u4e0e\u79d1\u5b66\u9662\u9662\u58eb\u5934\u8854\uff0c\u5982\u4eca\u53c8\u65a9\u83b7\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u58eb\uff0c\u6210\u4e3a\u53cc\u6599\u201c\u9662\u58eb\u201d\u3002<\/p>\n<p>\u503c\u5f97\u5173\u6ce8\u7684\u662f\uff0c\u9ebb\u7701\u7406\u5de5\u5927\u5b66\u7ec8\u8eab\u6559\u6388\u5f20\u950b\u5e74\u4ec536\u5c81\uff0c\u4ed6\u56e0\u57fa\u56e0\u4fee\u9970\u6280\u672fCRISPR-Cas9\u7684\u53d1\u5c55\u548c\u5e94\u7528\uff0c\u88ab\u89c6\u4e3a\u8bfa\u8d1d\u5c14\u5956\u7684\u70ed\u95e8\u4eba\u9009\u4e4b\u4e00\u3002\u5982\u4eca\u8fde\u7eed\u83b7\u5f97\u7f8e\u56fd\u4e24\u5927\u9662\u58eb\u5934\u8854\u540e\uff0c\u80fd\u5426\u65a9\u83b7\u4eca\u5e74\u7684\u8bfa\u8d1d\u5c14\u5956\u4ee4\u4eba\u671f\u5f85\u3002<\/p>\n<p><strong>\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821\u6559\u6388\u4e39\u626c<\/strong><\/p>\n<p align=\"center\"><img decoding=\"async\" src=\"http:\/\/scholarsupdate.hi2net.com\/upload2013\/20185219248578.jpg\" alt=\"\u4e39\u626c\u3001\u5f20\u950b\u3001\u5085\u5ac8\u60e0\u3001\u9ad8\u534e\u5065\u3001\u6587\u5c0f\u521a\u3001\u6797\u6d77\u5e06\u5f53\u90092018\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u58eb\" border=\"0\" \/><\/p>\n<p>\u4e39\u626c\u672c\u79d1\u5728\u5317\u4eac\u5927\u5b66\u7269\u7406\u7cfb\u5b66\u4e60\uff0c\u4e4b\u540e\u5728\u54e5\u4f26\u6bd4\u4e9a\u5927\u5b66\u653b\u8bfb\u751f\u7269\u5b66\u535a\u58eb\u5b66\u4f4d\uff0c\u5176\u4e3b\u8981\u7814\u7a76\u5185\u5bb9\u4e3a\u795e\u7ecf\u9012\u8d28\u5206\u6ccc\u4ee5\u53ca\u7a81\u89e6\u53ef\u5851\u6027\u7684\u5206\u5b50\u673a\u5236\u3002\u4e4b\u540e\uff0c\u5979\u5728\u6d1b\u514b\u83f2\u52d2\u5927\u5b66\u4ee5\u53ca\u54c8\u4f5b\u533b\u5b66\u9662\u8fdb\u884c\u535a\u58eb\u540e\u7814\u7a76\uff0c\u4e3b\u8981\u7814\u7a76\u89c6\u89c9\u7cfb\u7edf\u7684\u4fe1\u606f\u7f16\u7801\u3002<\/p>\n<p>\u4e39\u626c\u66fe\u7ecf\u83b7\u5f97\u963f\u5c14\u5f17\u96f7\u5fb7\u00b7P\u00b7\u65af\u9686\u7814\u7a76\u5956\u5b66\u91d1\uff08Alfred P. Sloan Research Fellowship\uff09\uff0c\u8d1d\u514b\u66fc\u9752\u5e74\u7814\u7a76\u8005\u5956\uff08Beckman Young Investigator Award\uff09\u7b49\u5956\u9879\u3002<\/p>\n<p align=\"center\"><strong>\u52a0\u5dde\u5927\u5b66\u65e7\u91d1\u5c71\u5206\u6821\u6559\u6388\u5085\u5ac8\u60e0<\/strong><\/p>\n<p align=\"center\"><img decoding=\"async\" src=\"http:\/\/5b0988e595225.cdn.sohucs.com\/images\/20180502\/02c15f5f4fd247b6815c65954b50aa97.jpeg\" alt=\"\u4e39\u626c\u3001\u5f20\u950b\u3001\u5085\u5ac8\u60e0\u3001\u9ad8\u534e\u5065\u3001\u6587\u5c0f\u521a\u3001\u6797\u6d77\u5e06\u5f53\u90092018\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u58eb\" \/><\/p>\n<p>\u5085\u5ac8\u60e0\u535a\u58eb1980\u5e74\u6bd5\u4e1a\u4e8e\u53f0\u6e7e\u4e2d\u5174\u5927\u5b66\uff0c\u53d6\u5f97\u98df\u54c1\u79d1\u5b66\u5b66\u4f4d\uff0c1986\u5e74\u6bd5\u4e1a\u4e8e\u4fc4\u4ea5\u4fc4\u5dde\u7acb\u5927\u5b66\uff0c\u83b7\u751f\u7269\u5316\u5b66\u4ee5\u53ca\u7ec6\u80de\u751f\u7269\u5b66\u5b66\u4f4d\u3002\u5728\u4fc4\u4ea5\u4fc4\u5dde\u7acb\u5927\u5b66\u8fdb\u884c\u4e09\u5e74\u535a\u58eb\u540e\u7814\u7a76\u4e4b\u540e\uff0c\u5085\u5ac8\u60e0\u8f6c\u5230\u8d1d\u52d2\u533b\u5b66\u9662\uff08Baylor College of Medicine\uff09\u7ee7\u7eed\u535a\u58eb\u540e\u7814\u7a76\uff0c\u4e3b\u8981\u7814\u7a76\u5185\u5bb9\u4e3a\u4eba\u7c7b\u57fa\u56e0\u7ec4\u3002\u7ed3\u675f\u535a\u58eb\u540e\u7814\u7a76\u4e4b\u540e\uff0c\u5979\u66fe\u5728\u4e1a\u754c\u5de5\u4f5c\u8fc7\u56db\u5e74\uff0c\u540e\u8fd4\u56de\u5b66\u672f\u754c\uff0c\u62c5\u4efb\u72b9\u4ed6\u5927\u5b66\u7814\u7a76\u52a9\u7406\u6559\u6388\u3002<\/p>\n<p>2002\u5e74\uff0c\u5979\u5728\u52a0\u5dde\u5927\u5b66\u65e7\u91d1\u5c71\u5206\u6821\u4e0e\u5408\u4f5c\u8005Louis Ptacek\u4e00\u540c\u7ec4\u5efa\u5b9e\u9a8c\u5ba4\uff0c\u4e3b\u8981\u7814\u7a76\u5185\u5bb9\u4e3a\uff1a\u5b9a\u4f4d\u4eba\u7c7b\u7761\u7720\u57fa\u56e0\uff0c\u63ed\u793a\u4eba\u7c7b\u7761\u7720\u8c03\u8282\u4ee5\u53ca\u4eba\u4f53\u8282\u5f8b\u7684\u5206\u5b50\u673a\u5236\uff0c\u7814\u7a76\u8131\u9ad3\u9798\u75be\u75c5\u7684\u5c0f\u9f20\u6a21\u578b\u4ee5\u53ca\u5bf9\u5065\u5eb7\u9ad3\u78f7\u8102\u6709\u5e2e\u52a9\u7684miRNA\u8fdb\u884c\u5206\u7c7b\u3002<\/p>\n<p align=\"center\"><strong>\u7f8e\u56fd\u5e03\u6717\u5927\u5b66\u6559\u6388\u9ad8\u534e\u5065<\/strong><\/p>\n<p align=\"center\"><img decoding=\"async\" src=\"http:\/\/5b0988e595225.cdn.sohucs.com\/images\/20180502\/c8e991dc6f774e27bb67f58651e6c886.jpeg\" alt=\"\u4e39\u626c\u3001\u5f20\u950b\u3001\u5085\u5ac8\u60e0\u3001\u9ad8\u534e\u5065\u3001\u6587\u5c0f\u521a\u3001\u6797\u6d77\u5e06\u5f53\u90092018\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u58eb\" \/><\/p>\n<p>\u9ad8\u534e\u5065\u6559\u63881982\u5e74\u6bd5\u4e1a\u4e8e\u897f\u5b89\u4ea4\u901a\u5927\u5b66\u5de5\u7a0b\u529b\u5b66\u7cfb\uff0c\u83b7\u5de5\u5b66\u5b66\u58eb\u5b66\u4f4d\u30021988\u5e74\u83b7\u54c8\u4f5b\u5927\u5b66\u5de5\u7a0b\u79d1\u5b66\u535a\u58eb\u5b66\u4f4d\uff0c2000\u5e74\u4efb\u65af\u5766\u798f\u5927\u5b66\u6559\u6388\uff0c2001\u5e74\u8d77\u62c5\u8d1f\u8054\u90a6\u5fb7\u56fdMax-Planck\u91d1\u5c5e\u6750\u6599\u7814\u7a76\u6240\u6240\u957f\uff0c2006\u5e741\u6708\u81f3\u4eca\u4efb\u7f8e\u56fd\u5e03\u6717\u5927\u5b66\u7ec8\u751f\u6559\u6388\u30022011\u5f53\u9009\u7f8e\u56fd\u56fd\u5bb6\u5de5\u7a0b\u9662\u9662\u58eb\u3002<\/p>\n<p>\u4ed6\u7684\u7814\u7a76\u9886\u57df\u5305\u542b\u4e86\u65ad\u88c2\u529b\u5b66\u3001\u8584\u819c\u529b\u5b66\u3001\u5de5\u7a0b\u53ca\u751f\u7269\u7cfb\u7edf\u7684\u7eb3\u7c73\u529b\u5b66\u3001\u4f4d\u9519\u53ca\u5851\u6027\u7406\u8bba\u7b49\u6750\u6599\u79d1\u5b66\u53ca\u56fa\u4f53\u529b\u5b66\u7b49\u3002\u9ad8\u534e\u5065\u5df2\u7ecf\u53d1\u8868\u5b66\u672f\u8bba\u6587300\u4f59\u7bc7\uff0cISI\u5f15\u752818600\u4f59\u6b21\uff0c\u5728\u4e16\u754c\u56fa\u4f53\u529b\u5b66\u9886\u57df\u5b66\u8005\u8fc7\u53bb20\u5e74\u4e2d\u7684\u5f15\u7528\u6392\u540d\u7b2c\u4e00\u3002\u9ad8\u534e\u5065\u662f\u76ee\u524d\u56fd\u9645\u4e0a60\u5c81\u4ee5\u4e0b\u56fa\u4f53\u529b\u5b66\u5bb6\u4e2d\u6700\u6770\u51fa\u7684\u4ee3\u8868\u3002\u57282012\u5e74\u56fd\u9645\u7406\u8bba\u4e0e\u5e94\u7528\u529b\u5b66\u8054\u5408\u4f1a\u4e0a\uff0c\u4ed6\u88ab\u6388\u4e88\u56db\u5e74\u4ec5\u4e00\u4eba\u7684\u4e16\u754c\u529b\u5b66\u754c\u6700\u9ad8\u8363\u8a89\u2014Rodney Hill\u56fa\u4f53\u529b\u5b66\u5956\u3002\u6388\u5956\u8bcd\u4e2d\u8bb2\u5230\u201c\u4ed6\u7684\u7814\u7a76\u6210\u679c\u5960\u5b9a\u5e76\u62d3\u5c55\u4e86\u73b0\u4ee3\u529b\u5b66\u7814\u7a76\u7684\u524d\u6cbf\u201d\u30022015\u5e74\uff0c\u4ed6\u5148\u540e\u83b7\u5f97\u7f8e\u56fd\u5de5\u7a0b\u79d1\u5b66\u534f\u4f1a\u7684\u6700\u9ad8\u5956\u2014William Prager\u5956\uff0c\u548c\u7f8e\u56fd\u673a\u68b0\u5de5\u7a0b\u5e08\u534f\u4f1a\u7684\u6750\u6599\u7c7b\u6700\u9ad8\u5956\u2014Nadai\u5956\u3002<\/p>\n<p><strong>\u8036\u9c81\u5927\u5b66\u6559\u6388\u6797\u6d77\u5e06<\/strong><\/p>\n<p align=\"center\"><img decoding=\"async\" src=\"http:\/\/5b0988e595225.cdn.sohucs.com\/images\/20180502\/e98e68c4c78940758174aee054413a03.jpeg\" alt=\"\u4e39\u626c\u3001\u5f20\u950b\u3001\u5085\u5ac8\u60e0\u3001\u9ad8\u534e\u5065\u3001\u6587\u5c0f\u521a\u3001\u6797\u6d77\u5e06\u5f53\u90092018\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u58eb\" \/><\/p>\n<p>\u6797\u6d77\u5e06\uff0c\u751f\u7269\u5b66\u5bb6\uff0c\u6d59\u6c5f\u6e29\u5dde\u6d1e\u5934\u4eba\u3002\u7f8e\u56fd\u8036\u9c81\u5927\u5b66\u5c24\u91d1\uff0d\u5e0c\u91d1\u65af\u8bb2\u5e2d\u6559\u6388\uff08\u7ec8\u8eab\uff09\u3001\u8036\u9c81\u5927\u5b66\u5e72\u7ec6\u80de\u4e2d\u5fc3\u521b\u59cb\u4e3b\u4efb\u3001\u8036\u9c81\u5927\u5b66\u533b\u5b66\u9662\u7ec6\u80de\u751f\u7269\u5b66\u7cfb\u3001\u9057\u4f20\u5b66\u7cfb\u3001\u5987\u4ea7\u79d1\u4e0e\u751f\u6b96\u79d1\u5b66\u7cfb\u6559\u6388\u3002<\/p>\n<p>\u6797\u6d77\u5e061982\u5e74\u83b7\u5f97\u590d\u65e6\u5927\u5b66\u751f\u7269\u5316\u5b66\u4e13\u4e1a\u5b66\u58eb\u5b66\u4f4d\uff1b1990\u5e74\u83b7\u5f97\u5eb7\u5948\u5c14\u5927\u5b66\u57fa\u56e0\u4e0e\u53d1\u80b2\u5b66\u4e13\u4e1a\u535a\u58eb\u5b66\u4f4d\uff1b1990-1994\u5e74\u5728\u7f8e\u56fd\u5361\u5185\u57fa\u7814\u7a76\u6240\u505a\u535a\u58eb\u540e\uff1b1994-2006\u5e74\u5728\u7f8e\u56fd\u675c\u514b\u5927\u5b66\u533b\u5b66\u9662\u5148\u540e\u4efb\u52a9\u7406\u6559\u6388\u3001\u7ec8\u8eab\u526f\u6559\u6388\u548c\u6559\u6388\uff1b2006\u5e74\u81f3\u4eca\u4efb\u8036\u9c81\u5927\u5b66\u533b\u5b66\u9662\u7ec6\u80de\u751f\u7269\u5b66\u7cfb\u6559\u6388\u3001\u9057\u4f20\u7cfb\u6559\u6388\u3001\u5987\u4ea7\u79d1\u7cfb\u6559\u6388\u3001\u5e72\u7ec6\u80de\u4e2d\u5fc3\u521b\u59cb\u4e3b\u4efb\uff1b2013\u5e747\u6708\u8d77\u517c\u4efb\u4e0a\u6d77\u79d1\u6280\u5927\u5b66\u514d\u75ab\u5316\u5b66\u7814\u7a76\u6240\u6559\u6388\uff1b2014\u5e743\u6708\u8d77\u517c\u4efb\u4e0a\u6d77\u79d1\u6280\u5927\u5b66\u751f\u547d\u79d1\u5b66\u4e0e\u6280\u672f\u5b66\u9662\u9662\u957f\u3002<\/p>\n<p>\u6797\u6d77\u5e06\u957f\u671f\u4ece\u4e8b\u5e72\u7ec6\u80de\u751f\u7269\u5b66\u3001\u751f\u6b96\u751f\u7269\u5b66\u3001RNA\u751f\u7269\u5b66\u3001\u4e0e\u8868\u89c2\u9057\u4f20\u5b66\u7684\u7814\u7a76\uff0c\u5e76\u5bf9\u8fd9\u4e9b\u9886\u57df\u4f5c\u51fa\u4e86\u91cd\u8981\u8d21\u732e\u3002\u4ed6\u53d1\u73b0\u4e86\u7b2c\u4e00\u4e2a\u63a7\u5236\u80da\u80ce\u7ec6\u80de\u5206\u88c2\u7684\u6bcd\u4f53\u6548\u5e94\u57fa\u56e0\uff0c\u8bc1\u660e\u4e86\u5e72\u7ec6\u80de\u975e\u5bf9\u79f0\u6027\u5206\u88c2\u7684\u81ea\u6211\u66f4\u65b0\u7684\u7406\u8bba\u4e0e\u5e72\u7ec6\u80de\u5fae\u73af\u5883\u5047\u8bf4\uff0c\u53d1\u73b0\u5e76\u547d\u540d\u4e86\u591a\u79cd\u5728\u4eba\u7c7b\u4e0e\u52a8\u3001\u690d\u7269\u754c\u5171\u6709\u7684\u5e72\u7ec6\u80de\u57fa\u56e0\uff0c\u5305\u62ec\u8457\u540d\u7684Argonaute\u57fa\u56e0\u5bb6\u7cfb\u3002\u53d1\u73b0\u5e76\u547d\u540d\u65b0\u7684\u4e00\u7c7b\u9057\u4f20\u8c03\u63a7\u5206\u5b50piRNA\uff0c\uff08piRNA\u51e0\u4e4e\u540c\u65f6\u4e5f\u88ab\u5176\u4ed6\u4e09\u4e2a\u5b9e\u9a8c\u5ba4\u53d1\u73b0\uff09\uff0c\u6b64\u53d1\u73b0\u88ab\u4e16\u754c\u9876\u5c16\u79d1\u5b66\u671f\u520a\u300a\u79d1\u5b66\u300b\uff08Science\uff09\u8bc4\u4e3a2006\u5e74\u5341\u5927\u79d1\u5b66\u7a81\u7834\u4e4b\u4e00\u3002<\/p>\n<p><strong>\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u6559\u6388\u6587\u5c0f\u521a<\/strong><\/p>\n<p align=\"center\"><img decoding=\"async\" src=\"http:\/\/5b0988e595225.cdn.sohucs.com\/images\/20180502\/04ae1fc943f149e882d59870ed2472f1.jpeg\" alt=\"\u4e39\u626c\u3001\u5f20\u950b\u3001\u5085\u5ac8\u60e0\u3001\u9ad8\u534e\u5065\u3001\u6587\u5c0f\u521a\u3001\u6797\u6d77\u5e06\u5f53\u90092018\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u58eb\" width=\"350\" \/><\/p>\n<p>\u6587\u5c0f\u521a\uff0c\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u6559\u6388\u30021977\u5e74\uff0c\u6587\u5c0f\u521a\u81ea\u9655\u897f\u7701\u897f\u5b89\u5e02\u7b2c\u56db\u5341\u516b\u4e2d\u5b66\u8003\u5165\u4e2d\u56fd\u79d1\u5b66\u6280\u672f\u5927\u5b66\u7269\u7406\u7cfb\uff0c\u901a\u8fc71981\u5e74\u5ea6\u4e2d\u7f8e\u7269\u7406\u8054\u5408\u8003\u8bd5\uff08CUSPEA\uff09\u8d74\u7f8e\u653b\u8bfb\u535a\u58eb\u5b66\u4f4d\uff0c\u540d\u5217\u5f53\u5e74CUSPEA\u8003\u8bd5\u7b2c\u4e00\u540d\u30021987\u5e74\u83b7\u5f97\u666e\u6797\u65af\u987f\u5927\u5b66\u7269\u7406\u535a\u58eb\u5b66\u4f4d\u3002\u5728\u666e\u6797\u65af\u987f\u5927\u5b66\uff0c\u6587\u5c0f\u521a\u5728\u7406\u8bba\u7269\u7406\u5b66\u5bb6\u7231\u5fb7\u534e\u00b7\u5a01\u6ed5\u6307\u5bfc\u4e0b\u5b66\u4e60\u8d85\u5f26\u7406\u8bba\u3002<\/p>\n<p>\u540e\u6765\uff0c\u4ed6\u4e0e\u7406\u8bba\u7269\u7406\u5b66\u5bb6\u7ea6\u7ff0\u00b7\u65bd\u91cc\u5f17\uff0c\u5f17\u6717\u514b\u00b7\u97e6\u5c14\u5207\u514b\uff0c\u5f90\u4e00\u9e3f\u5728\u52a0\u5dde\u5927\u5b66\u5723\u82ad\u82ad\u62c9\u5206\u6821\u7406\u8bba\u7269\u7406\u7814\u7a76\u6240\uff081987-1989\u5e74\uff09\u5408\u4f5c\uff0c\u5c06\u4ed6\u7684\u7814\u7a76\u9886\u57df\u8f6c\u53d8\u4e3a\u51dd\u805a\u4f53\u7269\u7406\u5b66\u3002<\/p>\n<p>\u66fe\u8363\u83b7\u6d77\u5916\u534e\u4eba\u7269\u7406\u5b66\u534f\u4f1a1994\u5e74\u4f18\u79c0\u9752\u5e74\u79d1\u5b66\u5bb6\u5956\u548c1992\u81f31997\u5e74\u7684\u65af\u6d1b\u6069\u5956\u30022016\u5e74\uff0c\u6587\u5c0f\u521a\u51ed\u501f\u7740\u201c\u62d3\u6251\u5e8f\u7406\u8bba\u548c\u5b83\u5728\u4f17\u591a\u7269\u7406\u7cfb\u7edf\u4e2d\u7684\u5e94\u7528\u201d\u83b7\u5f97\u5965\u5229\u5f17\u00b7E\u00b7\u5df4\u514b\u5229\u5956\uff08Oliver E. Buckley Condensed Matter Prize\uff09\uff0c\u8be5\u5956\u9879\u4e5f\u88ab\u8ba4\u4e3a\u662f\u51dd\u805a\u6001\u7269\u7406\u5b66\u7684\u6700\u9ad8\u5956\u9879\u3002\u6587\u5c0f\u521a\u8fd8\u517c\u4efb\u6e05\u534e\u5927\u5b66\u9ad8\u7b49\u7814\u7a76\u4e2d\u5fc3\u201c\u957f\u6c5f\u5b66\u8005\u5956\u52b1\u8ba1\u5212\u201d\u8bb2\u5ea7\u6559\u6388\u3002<\/p>\n<p><strong>\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u6559\u6388\u5f20\u950b<\/strong><\/p>\n<p align=\"center\"><img decoding=\"async\" src=\"http:\/\/5b0988e595225.cdn.sohucs.com\/images\/20180502\/220838dd530842ea8d9b47991b272ebc.jpeg\" alt=\"\u4e39\u626c\u3001\u5f20\u950b\u3001\u5085\u5ac8\u60e0\u3001\u9ad8\u534e\u5065\u3001\u6587\u5c0f\u521a\u3001\u6797\u6d77\u5e06\u5f53\u90092018\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u58eb\" \/><\/p>\n<p>\u5f20\u950b\uff0c\u7537\uff0c1982\u5e74\u51fa\u751f\u4e8e\u6cb3\u5317\u77f3\u5bb6\u5e84\uff0c\u7f8e\u56fd\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u535a\u58eb\uff0c\u662f\u5f53\u4eca\u6700\u4e3a\u4eba\u6240\u5173\u6ce8\u7684\u534e\u4eba\u751f\u7269\u5b66\u5bb6\u4e4b\u4e00\u3002\u4ed6\u6700\u8457\u540d\u7684\u5de5\u4f5c\u662f\u57fa\u56e0\u4fee\u9970\u6280\u672fCRISPR-Cas9\u7684\u53d1\u5c55\u548c\u5e94\u7528\uff0c\u7387\u5148\u83b7\u5f97\u4e86\u7f8e\u56fd\u4e13\u5229\uff0c\u5e76\u88ab\u89c6\u4e3a\u8bfa\u8d1d\u5c14\u5956\u7684\u70ed\u95e8\u4eba\u9009\u4e4b\u4e00\u3002<\/p>\n<p>2004\u5e74\u83b7\u5f97\u54c8\u4f5b\u5927\u5b66\u5316\u5b66\u4e0e\u7269\u7406\u5b66\u5b66\u58eb\u5b66\u4f4d\uff1b2009\u5e74\u83b7\u5f97\u65af\u5766\u798f\u5927\u5b66\u5316\u5b66\u53ca\u751f\u7269\u5de5\u7a0b\u535a\u58eb\u5b66\u4f4d\uff1b2011\u5e74\u4ed6\u52a0\u5165MIT\uff0c\u540c\u65f6\u5728\u9ea6\u6208\u6587\u8111\u79d1\u5b66\u7814\u7a76\u6240\uff08McGovern Institute\uff09\u5927\u8111\u4e0e\u8ba4\u77e5\u79d1\u5b66\u90e8\u95e8\uff0c\u4ee5\u53ca\u535a\u5fb7\u7814\u7a76\u6240\uff08Broad Institute\uff09\u4ece\u4e8b\u79d1\u7814\u5de5\u4f5c\uff1b<\/p>\n<p>2013\u5e74\uff0c\u4ed6\u7684\u5b9e\u9a8c\u5ba4\u5f00\u53d1\u51fa\u521b\u65b0\u6027CRISPR\/Cas\u7cfb\u7edf\uff0c\u5927\u5e45\u5ea6\u63d0\u9ad8\u4e86\u7f16\u8f91\u57fa\u56e0\u7684\u53ef\u9760\u6027\u548c\u6548\u7387\uff0c\u800c\u5f15\u8d77\u56fd\u9645\u5173\u6ce8\u548c\u5e76\u56e0\u4ed6\u7a81\u7834\u6027\u7684\u7814\u7a76\u6210\u679c\u800c\u83b7\u5f97\u5404\u79cd\u8363\u8a89\uff1b2014\u5e74\uff0c\u88ab\u300a\u81ea\u7136\u300b\u6742\u5fd7\u8bc4\u9009\u4e3a2013\u5e74\u5e74\u5ea6\u5341\u5927\u79d1\u5b66\u4eba\u7269\u4e4b\u4e00\uff1b2015\u5e74\uff0c\u83b7\u5f97\u201c\u5e74\u5ea6\u6ce2\u58eb\u987f\u4eba\u201d\u63d0\u540d\uff1b2016\u5e741\u6708\uff0c\u88ab\u6c64\u68ee\u8def\u900f\u8bc4\u4e3a2015\u5e74\u5168\u4e16\u754c19\u4f4d\u6700\u5177\u5f71\u54cd\u529b\u7684\u79d1\u5b66\u5bb6\u4e4b\u4e00\u3002\u540c\u65f6\uff0c\u4ed6\u662f\u540d\u5355\u4e2d\u552f\u4e00\u7684\u751f\u7269\u533b\u5b66\u5de5\u7a0b\u5b66\u8005\uff0c\u4e5f\u662f\u6700\u5e74\u8f7b\u7684\u79d1\u5b66\u5bb6\uff1b2016\u5e743\u6708\uff0c\u83b7\u5f97\u52a0\u62ff\u5927\u76d6\u5c14\u5fb7\u7eb3\u56fd\u9645\u5956\uff1b2016\u5e749\u670821\u65e5\uff0c\u5165\u56f4\u6c64\u68ee\u8def\u900f\u5316\u5b66\u9886\u57df\u201c\u5f15\u6587\u6842\u51a0\u5956\u201d\uff0c\u88ab\u89c6\u4e3a\u8bfa\u8d1d\u5c14\u5956\u7684\u70ed\u95e8\u4eba\u9009\u3002<\/p>\n<p>2017\u5e74\u664b\u5347\u4e3a\u7f8e\u56fd\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u7406\u5b66\u9662\u7ec8\u8eab\u6559\u6388 \u30022017\u5e748\u670815\u65e5\uff0c\u5f20\u950b\u83b7\u963f\u5c14\u4f2f\u5c3c\u751f\u7269\u533b\u5b66\u5956\uff0c\u6210\u4e3a\u5386\u53f2\u4e0a\u7b2c\u4e8c\u540d\u83b7\u5f97\u6b64\u5956\u9879\u7684\u534e\u4eba\u5b66\u8005\u3002<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>2018\u5e745\u67081\u65e5\uff0c\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u5b98\u7f51\u516c\u5e03\u4e86\u65b0\u5f53\u9009\u9662\u58eb\u540d\u5355\u3002\u56e0\u5728\u539f\u521b\u6027\u7814\u7a76\u65b9\u9762\u7684\u6770\u51fa\u8d21\u732e\u4e0e\u6301\u7eed\u6210\u5c31\uff0c84\u540d\u7f8e\u56fd &hellip; <a href=\"https:\/\/www.sandiegochinesepress.com\/press\/%e4%b8%b9%e6%89%ac%e3%80%81%e5%bc%a0%e9%94%8b%e3%80%81%e5%82%85%e5%ab%88%e6%83%a0%e3%80%81%e9%ab%98%e5%8d%8e%e5%81%a5%e3%80%81%e6%96%87%e5%b0%8f%e5%88%9a%e3%80%81%e6%9e%97%e6%b5%b7%e5%b8%86%e5%bd%93\/.html\" class=\"more-link\">\u7ee7\u7eed\u9605\u8bfb<span class=\"screen-reader-text\">\u4e39\u626c\u3001\u5f20\u950b\u3001\u5085\u5ac8\u60e0\u3001\u9ad8\u534e\u5065\u3001\u6587\u5c0f\u521a\u3001\u6797\u6d77\u5e06\u5f53\u90092018\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u58eb<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":1300030,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[40],"tags":[],"class_list":["post-1300029","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-us_news"],"_links":{"self":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/1300029","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/comments?post=1300029"}],"version-history":[{"count":0,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/1300029\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/media\/1300030"}],"wp:attachment":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/media?parent=1300029"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/categories?post=1300029"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/tags?post=1300029"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}