{"id":1411319,"date":"2019-01-25T17:39:10","date_gmt":"2019-01-26T01:39:10","guid":{"rendered":"http:\/\/www.sandiegochinesepress.com\/press\/?p=1411319"},"modified":"2019-01-25T17:43:44","modified_gmt":"2019-01-26T01:43:44","slug":"ucsd-%e7%a0%94%e7%a9%b6%e4%ba%ba%e5%91%98%e9%a6%96%e6%ac%a1%e4%bd%bf%e7%94%a8crispr-cas9%e6%8e%a7%e5%88%b6%e5%b0%8f%e9%bc%a0%e7%9a%84%e9%81%97%e4%bc%a0%ef%bc%88%e5%9b%be%ef%bc%89","status":"publish","type":"post","link":"https:\/\/www.sandiegochinesepress.com\/press\/ucsd-%e7%a0%94%e7%a9%b6%e4%ba%ba%e5%91%98%e9%a6%96%e6%ac%a1%e4%bd%bf%e7%94%a8crispr-cas9%e6%8e%a7%e5%88%b6%e5%b0%8f%e9%bc%a0%e7%9a%84%e9%81%97%e4%bc%a0%ef%bc%88%e5%9b%be%ef%bc%89\/.html","title":{"rendered":"UCSD \u7814\u7a76\u4eba\u5458\u9996\u6b21\u4f7f\u7528CRISPR\/CAS9\u63a7\u5236\u5c0f\u9f20\u7684\u9057\u4f20\uff08\u56fe\uff09"},"content":{"rendered":"

\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\uff08UCSD\uff09\u7684\u7814\u7a76\u4eba\u5458\u9996\u6b21\u4f7f\u7528CRISPR\/CAS9\u63a7\u5236\u5c0f\u9f20\u7684\u9057\u4f20\u3002\u8be5\u7814\u53d1\u6280\u672f\u4e3a\u556e\u9f7f\u7c7b\u52a8\u7269\u7684\u4eba\u7c7b\u75be\u75c5\u7814\u7a76\u63d0\u4f9b\u4e86\u5f3a\u6709\u529b\u7684\u65b0\u57fa\u56e0\u5de5\u5177\u3002<\/p>\n

\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u7684\u751f\u7269\u5b66\u5bb6\u5f00\u53d1\u4e86\u4e16\u754c\u4e0a\u7b2c\u4e00\u79cd\u57fa\u4e8eCRISPR\/CAS9\u7684\u65b9\u6cd5\u6765\u63a7\u5236\u54fa\u4e73\u52a8\u7269\u7684\u9057\u4f20\u3002<\/p>\n

\"\"\u4e3b\u8981\u5f00\u53d1\u4eba\u5458\uff1a\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u7814\u7a76\u751fHannah Grunwald\u548c\u52a9\u7406\u6559\u6388Kimberly Cooper\u3002<\/p>\n

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Cooper\u8bf4\uff1a\u201c\u6211\u4eec\u7684\u52a8\u673a\u662f\u5c06\u5176\u5f00\u53d1\u6210\u5b9e\u9a8c\u5ba4\u7814\u7a76\u4eba\u5458\u63a7\u5236\u5c0f\u9f20\u591a\u57fa\u56e0\u9057\u4f20\u7684\u5de5\u5177\u3002\u201d\u201c\u968f\u7740\u8fdb\u4e00\u6b65\u7684\u53d1\u5c55\uff0c\u6211\u4eec\u8ba4\u4e3a\u5c06\u6709\u53ef\u80fd\u4f7f\u590d\u6742\u7684\u4eba\u7c7b\u9057\u4f20\u75be\u75c5\u7684\u52a8\u7269\u6a21\u578b\uff0c\u5982\u5173\u8282\u708e\u548c\u764c\u75c7\uff0c\u8fd9\u662f\u76ee\u524d\u4e0d\u53ef\u80fd\u7684\u3002\u201d<\/p>\n

\u4e3a\u4e86\u8bc1\u660e\u5728\u5c0f\u9f20\u8eab\u4e0a\u7684\u53ef\u884c\u6027\uff0c\u7814\u7a76\u4eba\u5458\u5c06\u4e00\u79cd\u6d3b\u8dc3\u7684\u57fa\u56e0\u201c\u6a21\u4eff\u201dDNA\u5143\u7d20\u8bbe\u8ba1\u6210\u63a7\u5236\u6bdb\u53d1\u989c\u8272\u7684\u916a\u6c28\u9178\u9176\u57fa\u56e0\u3002\u5f53copycat\u5143\u7d20\u7834\u574f\u8001\u9f20\u57fa\u56e0\u7684\u4e24\u4e2a\u62f7\u8d1d\u65f6\uff0c\u539f\u672c\u5e94\u8be5\u662f\u9ed1\u8272\u7684\u6bdb\u53d1\u5c31\u53d8\u6210\u4e86\u767d\u8272\uff0c\u8fd9\u663e\u7136\u662f\u4ed6\u4eec\u65b9\u6cd5\u6210\u529f\u7684\u8bc1\u660e\u3002\u6a21\u4eff\u5143\u7d20\u7684\u8bbe\u8ba1\u4e5f\u4f7f\u5f97\u5b83\u4e0d\u80fd\u72ec\u81ea\u5728\u79cd\u7fa4\u4e2d\u4f20\u64ad\uff0c\u800c\u6606\u866b\u7684crispr\/cas9\u201c\u57fa\u56e0\u9a71\u52a8\u201d\u7cfb\u7edf\u5219\u5efa\u7acb\u5728\u4e00\u4e2a\u76f8\u4f3c\u7684\u6f5c\u5728\u5206\u5b50\u673a\u5236\u4e4b\u4e0a\u3002<\/p>\n

\u5728\u4e3a\u671f\u4e24\u5e74\u7684\u9879\u76ee\u671f\u95f4\uff0c\u7814\u7a76\u4eba\u5458\u4f7f\u7528\u5404\u79cd\u7b56\u7565\u6765\u786e\u5b9a\u590d\u5236\u7684\u5143\u7d20\u53ef\u4ee5\u4ece\u4e00\u4e2a\u67d3\u8272\u4f53\u590d\u5236\u5230\u53e6\u4e00\u4e2a\u67d3\u8272\u4f53\uff0c\u4ee5\u4fee\u590dcrispr\/cas9\u6240\u9488\u5bf9\u7684DNA\u65ad\u88c2\u3002\u7ed3\u679c\uff0c\u6700\u521d\u53ea\u51fa\u73b0\u5728\u4e24\u6761\u67d3\u8272\u4f53\u4e2d\u7684\u4e00\u6761\u4e0a\u7684\u5143\u7d20\u88ab\u590d\u5236\u5230\u53e6\u4e00\u6761\u67d3\u8272\u4f53\u4e0a\u3002\u5728\u5176\u4e2d\u4e00\u4e2a\u5bb6\u5ead\u4e2d\uff0c\u591a\u8fbe86%\u7684\u540e\u4ee3\u7ee7\u627f\u4e86\u6765\u81ea\u5973\u6027\u7236\u6bcd\u7684\u6a21\u4eff\u5143\u7d20\uff0c\u800c\u4e0d\u662f\u901a\u5e38\u768450%\u3002<\/p>\n

\u9898\u56fe\u4e3a\u5c0f\u9f20\u6a21\u4eff\u56fe\u3002<\/p>\n

\u8fd9\u79cd\u65b0\u65b9\u6cd5\u5728\u96cc\u9f20\u4ea7\u5375\u671f\u95f4\u6709\u6548\uff0c\u4f46\u5728\u96c4\u9f20\u7cbe\u5b50\u751f\u4ea7\u671f\u95f4\u65e0\u6548\u3002\u8fd9\u53ef\u80fd\u662f\u7531\u4e8e\u7537\u6027\u548c\u5973\u6027\u51cf\u6570\u5206\u88c2\u7684\u65f6\u95f4\u4e0d\u540c\uff0c\u8fd9\u662f\u4e00\u4e2a\u6b63\u5e38\u914d\u5bf9\u67d3\u8272\u4f53\u4ee5\u6d17\u724c\u57fa\u56e0\u7ec4\u7684\u8fc7\u7a0b\uff0c\u53ef\u80fd\u6709\u52a9\u4e8e\u8fd9\u79cd\u5de5\u7a0b\u590d\u5236\u4e8b\u4ef6\u3002<\/p>\n

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\u5e93\u73c0\u548c\u5979\u5b9e\u9a8c\u5ba4\u7684\u6210\u5458\u4eec\u73b0\u5728\u5f00\u59cb\u57fa\u4e8e\u4e00\u4e2a\u5355\u4e00\u57fa\u56e0\u7684\u54fa\u4e73\u52a8\u7269\u4e3b\u52a8\u9057\u4f20\u6210\u529f\uff0c\u5e76\u8bd5\u56fe\u5c06\u8be5\u5de5\u5177\u6269\u5c55\u5230\u591a\u4e2a\u57fa\u56e0\u548c\u7279\u6027\u3002<\/p>\n

\u201c\u6211\u4eec\u5df2\u7ecf\u8bc1\u660e\uff0c\u6211\u4eec\u53ef\u4ee5\u5c06\u4e00\u4e2a\u57fa\u56e0\u578b\u4ece\u6742\u5408\u5b50\u8f6c\u6362\u4e3a\u7eaf\u5408\u5b50\u3002\u73b0\u5728\u6211\u4eec\u60f3\u770b\u770b\u6211\u4eec\u662f\u5426\u80fd\u6709\u6548\u5730\u63a7\u5236\u52a8\u7269\u4e09\u4e2a\u57fa\u56e0\u7684\u9057\u4f20\u3002\u5e93\u73c0\u8bf4\uff1a\u201c\u5982\u679c\u8fd9\u79cd\u65b9\u6cd5\u80fd\u540c\u65f6\u5e94\u7528\u4e8e\u591a\u79cd\u57fa\u56e0\uff0c\u5b83\u5c06\u5f7b\u5e95\u6539\u53d8\u5c0f\u9f20\u7684\u9057\u4f20\u5b66\u3002\u201d<\/p>\n

\u867d\u7136\u8fd9\u9879\u65b0\u6280\u672f\u662f\u4e3a\u5b9e\u9a8c\u5ba4\u7814\u7a76\u5f00\u53d1\u7684\uff0c\u4f46\u6709\u4e9b\u4eba\u5df2\u7ecf\u9884\u89c1\u5230\u672a\u6765\u7684\u57fa\u56e0\u9a71\u52a8\u5c06\u5728\u91ce\u5916\u5efa\u7acb\u5728\u8fd9\u79cd\u65b9\u6cd5\u7684\u57fa\u7840\u4e0a\uff0c\u4ee5\u52aa\u529b\u6062\u590d\u5305\u62ec\u556e\u9f7f\u52a8\u7269\u5728\u5185\u7684\u5165\u4fb5\u7269\u79cd\u6240\u7834\u574f\u7684\u751f\u6001\u7cfb\u7edf\u4e2d\u81ea\u7136\u751f\u7269\u591a\u6837\u6027\u7684\u5e73\u8861\u3002<\/p>\n

Bier\u8bf4\uff1a\u201c\u901a\u8fc7\u8fdb\u4e00\u6b65\u7684\u6539\u8fdb\uff0c\u5e94\u8be5\u6709\u53ef\u80fd\u5f00\u53d1\u57fa\u56e0\u9a71\u52a8\u6280\u672f\uff0c\u4ee5\u6539\u53d8\u6216\u53ef\u80fd\u51cf\u5c11\u4f5c\u4e3a\u75be\u75c5\u8f7d\u4f53\u6216\u5bf9\u672c\u571f\u7269\u79cd\u9020\u6210\u635f\u5bb3\u7684\u54fa\u4e73\u52a8\u7269\u79cd\u7fa4\u3002\u201d<\/p>\n

\u8fd9\u4e9b\u6570\u636e\u8fd8\u8868\u660e\uff0c\u5728\u91ce\u5916\u5b9e\u9645\u4f7f\u7528\u6240\u9700\u7684\u6280\u672f\u6539\u8fdb\uff0c\u4f7f\u4eba\u4eec\u6709\u65f6\u95f4\u4ed4\u7ec6\u8003\u8651\u8fd9\u79cd\u65b0\u6280\u672f\u7684\u54ea\u4e9b\u5e94\u7528\u53ef\u4ee5\u548c\u5e94\u8be5\u5f97\u5230\u5b9e\u65bd\u3002\u7136\u800c\uff0c\u7814\u7a76\u4eba\u5458\u6ce8\u610f\u5230\uff0c\u4ed6\u4eec\u7684\u7814\u7a76\u7ed3\u679c\u663e\u793a\u51fa\u4e86\u5de8\u5927\u7684\u8fdb\u6b65\uff0c\u53ef\u80fd\u5df2\u7ecf\u51cf\u5c11\u4e86\u63a8\u8fdb\u4eba\u7c7b\u75be\u75c5\u751f\u7269\u533b\u5b66\u7814\u7a76\u548c\u4e86\u89e3\u5176\u4ed6\u7c7b\u578b\u590d\u6742\u9057\u4f20\u7279\u5f81\u6240\u9700\u7684\u65f6\u95f4\u3001\u6210\u672c\u548c\u52a8\u7269\u6570\u91cf\u3002<\/p>\n

Cooper\u8bf4\uff1a\u201c\u6211\u4eec\u4e5f\u6709\u5174\u8da3\u4e86\u89e3\u8fdb\u5316\u7684\u673a\u5236\u3002\u5bf9\u4e8e\u67d0\u4e9b\u5df2\u7ecf\u8fdb\u5316\u8d85\u8fc710\u82f1\u91cc\u7684\u7279\u6027\u3002\u201c<\/p>\n

\uff08\u7f8e\u56fd\u534e\u6587\u7f51 \u5723\u5730\u4e9a\u54e5\u534e\u6587\u7f51 \u534e\u6587\u98ce\u91c7\u7f16\u53d1 USChinesePress.com SanDiegoChinesePress.com\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"

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