{"id":1487535,"date":"2021-07-20T11:34:31","date_gmt":"2021-07-20T18:34:31","guid":{"rendered":"http:\/\/www.sandiegochinesepress.com\/press\/?p=1487535"},"modified":"2021-07-20T12:44:48","modified_gmt":"2021-07-20T19:44:48","slug":"%e7%a0%94%e7%a9%b6%e4%ba%ba%e5%91%98%e5%8f%91%e7%8e%b0%e6%89%80%e6%9c%89%e7%99%8c%e7%97%87%e9%83%bd%e6%9c%89%e5%85%b1%e5%90%8c%e7%82%b9%ef%bc%88%e5%9b%be%ef%bc%89","status":"publish","type":"post","link":"https:\/\/www.sandiegochinesepress.com\/press\/%e7%a0%94%e7%a9%b6%e4%ba%ba%e5%91%98%e5%8f%91%e7%8e%b0%e6%89%80%e6%9c%89%e7%99%8c%e7%97%87%e9%83%bd%e6%9c%89%e5%85%b1%e5%90%8c%e7%82%b9%ef%bc%88%e5%9b%be%ef%bc%89\/.html","title":{"rendered":"\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u6240\u6709\u764c\u75c7\u90fd\u6709\u5171\u540c\u70b9\uff08\u56fe\uff09"},"content":{"rendered":"<p>\u7f8e\u56fdNIH\u764c\u75c7\u5b66\u9662\u65b0\u95fb\u62a5\u9053\uff1a\u6839\u636e\u897f\u5948\u5065\u5eb7\u4e2d\u5fc3\u79d1\u5b66\u5bb6\u7684\u6700\u65b0\u7814\u7a76\uff0c\u6240\u6709\u7684\u764c\u75c7\u53ea\u5206\u4e3a\u4e24\u7c7b\uff0c\u8fd9\u4e00\u53d1\u73b0\u53ef\u80fd\u4e3a\u6cbb\u7597\u6700\u5177\u653b\u51fb\u6027\u548c\u65e0\u6cd5\u6cbb\u7597\u7684\u764c\u75c7\u63d0\u4f9b\u4e00\u79cd\u65b0\u7684\u7b56\u7565\u3002<\/p>\n<p>\u62a5\u9053\u8bf4\uff1a\u5728\u672c\u6708\u8fdb\u884c\u7684\u4e00\u9879\u5173\u4e8e\u764c\u7ec6\u80de\u7684\u65b0\u7814\u7a76\u4e2d\uff0c\u897f\u5948\u5065\u5eb7\uff08Sinai 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Bremner\u5b9e\u9a8c\u5ba4\u535a\u58eb\u540e\u7814\u7a76\u5458Joel Pearson\u8bf4\uff0c\u6cbb\u7597\u8fd9\u4e9b\u764c\u75c7\u7684\u7597\u6cd5\u53ef\u80fd\u5bf9\u60a3\u8005\u751f\u5b58\u5c06\u4ea7\u751f\u6df1\u8fdc\u5f71\u54cd\u3002<\/p>\n<p>Pearson\u8bf4\uff1a\u201c\u6211\u4eec\u53d1\u73b0\u7684\u7b80\u5355\u7684\u4e8c\u5143\u6cd5\u5219\u53ef\u80fd\u4f1a\u63ed\u793a\u51fa\u6cbb\u7597\u8bb8\u591a\u764c\u75c7\u7c7b\u578b\u7684\u7b56\u7565\uff0c\u8fd9\u4e9b\u764c\u75c7\u7c7b\u578b\u5c5e\u4e8eYAPoff\u6216YAPon\u8d85\u7c7b\u3002\u201d \u6b64\u5916\uff0c\u7531\u4e8e\u764c\u75c7\u7684\u72b6\u6001\u9003\u907f\u6cbb\u7597\uff0c\u56e0\u6b64\u6709\u529e\u6cd5YAPoff\u6216YAPon\u7684\u6cbb\u7597\u90fd\u53ef\u80fd\u6210\u4e3a\u963b\u6b62\u8fd9\u79cd\u764c\u75c7\u8f6c\u53d8\u7c7b\u578b\u4ee5\u62b5\u6297\u836f\u7269\u6cbb\u7597\u7684\u4e00\u822c\u65b9\u6cd5\u3002\u201d<\/p>\n<p>\u7814\u7a76\u4eba\u5458\u5e0c\u671b\u901a\u8fc7\u63a8\u65ad\u8fd9\u4e9b\u7c7b\u578b\u764c\u75c7\u7684\u5171\u540c\u5f31\u70b9\uff0c\u6709\u53ef\u80fd\u5f00\u53d1\u51fa\u65b0\u7684\u6cbb\u7597\u65b9\u6cd5\u5e76\u6539\u5584\u60a3\u8005\u7684\u9884\u540e\u3002<\/p>\n<p>\u8fd9\u9879\u5de5\u4f5c\u4e3b\u8981\u7531\u52a0\u62ff\u5927\u536b\u751f\u7814\u7a76\u9662\uff08CIHR\uff09\u3001\u764c\u75c7\u7814\u7a76\u534f\u4f1a\u548c\u514b\u91cc\u59c6\u6bd4\u5c14\u57fa\u91d1\u4f1a\u8d44\u52a9\u3002<\/p>\n<p>\u53c2\u8003\u6587\u732e\uff1a2021.<a href=\"https:\/\/doi.org\/10.1016\/j.ccell.2021.06.016\" target=\"_blank\" rel=\"noopener\">10.1016\/j.ccell.2021.06.016, \u4f5c\u8005\uff1aPearson JD\uff0cHuang K\uff0cPacal M\u7b49\u3002<\/a><\/p>\n<p><strong>Yes\u76f8\u5173\u86cb\u767d(Yes-associated protein, YAP)<\/strong>\u662f\u4e00\u79cd\u5177\u6709\u591a\u79cd\u529f\u80fd\u7684\u7ec6\u80de\u5185\u8fde\u63a5\u86cb\u767d\u548c\u8f6c\u5f55\u5171\u6fc0\u6d3b\u56e0\u5b50, \u6700\u65e9\u7531Sudol\u53d1\u73b0\u3002\u8fd1\u5e74\u7814\u7a76\u53d1\u73b0, Yes\u76f8\u5173\u86cb\u767d\u7684\u8868\u8fbe\u589e\u9ad8\u4ee5\u53ca\u6d3b\u6027\u589e\u5f3a\u53ef\u4fc3\u8fdb\u80bf\u7624\u7684\u53d1\u751f\u548c\u53d1\u5c55, \u63d0\u793a\u5176\u6f5c\u5728\u7684\u81f4\u764c\u6027\u3002\u636e\u6587\u732e\u62a5\u9053\uff0cYes\u76f8\u5173\u86cb\u767d\u5728\u809d\u764c\u3001\u80c3\u764c\u7b49\u80bf\u7624\u7ec4\u7ec7\u4e2d\u8868\u8fbe\u6c34\u5e73\u589e\u9ad8\u3002<\/p>\n<p>\uff08\u7f8e\u56fd\u534e\u6587\u7f51 \u5723\u5730\u4e9a\u54e5\u534e\u6587\u7f51\u7f16\u53d1 USChinesePress.com SanDiegoChinesePress.com\uff09<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6839\u636e\u897f\u5948\u5065\u5eb7\u4e2d\u5fc3\u79d1\u5b66\u5bb6\u7684\u6700\u65b0\u7814\u7a76\uff0c\u6240\u6709\u7684\u764c\u75c7\u53ea\u5206\u4e3a\u4e24\u7c7b&#8230;..<\/p>\n","protected":false},"author":3,"featured_media":1487536,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[],"class_list":["post-1487535","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science_technology_education"],"_links":{"self":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/1487535","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/comments?post=1487535"}],"version-history":[{"count":0,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/1487535\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/media\/1487536"}],"wp:attachment":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/media?parent=1487535"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/categories?post=1487535"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/tags?post=1487535"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}