\u9898\u56fe\u4e3a\u7f8e\u56fd\u534e\u76db\u987f\u5927\u5b66\u8def\u6613\u65af\u533b\u5b66\u9662\uff08Washington University School of Medicine in St. Louis\uff09\u7684\u7814\u7a76\u4eba\u5458\u6b63\u5728\u9ad8\u5ea6\u751f\u7269\u5b89\u5168\u6761\u4ef6\u4e0b\u7814\u7a762019\u51a0\u72b6\u75c5\u6bd2\u75be\u75c5\u6297\u4f53\u3002\uff08\u8be5\u6821\u5b98\u7f51\u56fe\uff09<\/p>\n
\u7f8e\u56fd\u534e\u76db\u987f\u5927\u5b66\u8def\u6613\u65af\u533b\u5b66\u9662\u79f0\uff0c\u8be5\u6821\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u4e86\u4e00\u79cd\u540d\u4e3aSARS2-38\u7684\u6297\u4f53\uff0c\u5176\u53ef\u8f7b\u6613\u4e2d\u548c\u6240\u6709\u5df2\u77e5\u76846\u79cdCOVID-19\uff082019\u51a0\u72b6\u75c5\u6bd2\u75be\u75c5\uff09\u53d8\u5f02\u682a\uff0c\u5305\u62ec\u5bf9\u6297\u4f53\u62b5\u6297\u529b\u6700\u5f3a\u7684Beta\u53d8\u5f02\u682a\u5728\u5185\u3002<\/p>\n
\u62a5\u9053\u79f0\uff0c\u4eca\u5929\u5bfc\u81f4\u75c5\u6bd22019\u51a0\u72b6\u75c5\u6bd2\u75be\u75c5\u4e0e2019\u5e7412\u6708\u9996\u6b21\u53d1\u75c5\u7684\u75c5\u6bd2\u4e0d\u540c\u3002\u73b0\u5728\u8bb8\u591a\u75c5\u6bd2\u53d8\u4f53\u90e8\u5206\u62b5\u6297\u57fa\u4e8e\u539f\u59cb\u75c5\u6bd2\u5f00\u53d1\u7684\u6297\u4f53\u7597\u6cd5\u3002\u968f\u7740\u5927\u6d41\u884c\u7684\u7ee7\u7eed\uff0c\u4e0d\u53ef\u907f\u514d\u5730\u4f1a\u51fa\u73b0\u66f4\u591a\u7684\u53d8\u79cd\uff0c\u8010\u836f\u6027\u95ee\u9898\u53ea\u4f1a\u8d8a\u6765\u8d8a\u4e25\u91cd\u3002<\/p>\n
\u5723\u8def\u6613\u65af\u534e\u76db\u987f\u5927\u5b66\u533b\u5b66\u9662\u7684\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u7684\u8fd9\u79cd\u6297\u4f53\uff0c\u5728\u4f4e\u5242\u91cf\u4e0b\u5bf9\u591a\u79cd\u75c5\u6bd2\u53d8\u4f53\u5177\u6709\u9ad8\u5ea6\u4fdd\u62a4\u4f5c\u7528\u3002\u6b64\u5916\uff0c\u6297\u4f53\u9644\u7740\u5728\u75c5\u6bd2\u7684\u67d0\u4e00\u90e8\u5206\uff0c\u800c\u8be5\u90e8\u5206\u5728\u4e0d\u540c\u7684\u53d8\u79cd\u4e4b\u95f4\u51e0\u4e4e\u6ca1\u6709\u5dee\u5f02\uff0c\u8fd9\u610f\u5473\u7740\u4e0d\u592a\u53ef\u80fd\u5728\u8be5\u90e8\u4f4d\u4ea7\u751f\u8010\u836f\u6027\u3002<\/p>\n
\u8fd9\u4e00\u7814\u7a76\u53d1\u73b0\u7684\u8bba\u6587\u5df2\u7ecf\u53d1\u8868\u5728\u300a\u514d\u75ab\u300b\u6742\u5fd7\u7684\u5728\u7ebf\u7248\u4e0a\uff0c\u8fd9\u6807\u5fd7\u5bf9\u65b0\u51a0\u75be\u75c5\u7684\u65b0\u7684\u57fa\u4e8e\u6297\u4f53\u7684\u7597\u6cd5\u5f00\u53d1\u8fc8\u51fa\u65b0\u7684\u4e00\u6b65\uff0c\u8fd9\u79cd\u7597\u6cd5\u5728\u75c5\u6bd2\u53d8\u5f02\u65f6\u4e0d\u592a\u53ef\u80fd\u5931\u53bb\u6548\u529b\u3002<\/p>\n
\u201c\u76ee\u524d\u7684\u6297\u4f53\u53ef\u80fd\u5bf9\u4e00\u4e9b\u4f46\u4e0d\u662f\u6240\u6709\u7684\u53d8\u79cd\u6709\u6548\uff0c\u201d \u5171\u540c\u4f5c\u8005\uff0cHerbert Gasser\u6559\u6388\u7684\u533b\u5b66\u7814\u7a76\u5c0f\u7ec4\u6210\u5458 Michael S. Diamond\u535a\u58eb\u79f0\u3002\u201c\u75c5\u6bd2\u53ef\u80fd\u4f1a\u968f\u7740\u65f6\u95f4\u548c\u7a7a\u95f4\u7684\u63a8\u79fb\u800c\u7ee7\u7eed\u8fdb\u5316\u3002\u62e5\u6709\u5e7f\u6cdb\u4e2d\u548c\u7684\u3001\u6709\u6548\u7684\u6297\u4f53\uff0c\u8fd9\u4e9b\u6297\u4f53\u53ef\u4ee5\u5355\u72ec\u5de5\u4f5c\uff0c\u5e76\u4e14\u53ef\u4ee5\u914d\u5bf9\u4ee5\u5f62\u6210\u65b0\u7684\u7ec4\u5408\uff0c\u8fd9\u53ef\u80fd\u4f1a\u963b\u6b62\u8010\u836f\u6027\u3002\u201d<\/p>\n
\u5bfc\u81f42019\u51a0\u72b6\u75c5\u6bd2\u75be\u75c5\u7684SARS COV-2\u4f7f\u7528\u4e00\u79cd\u53eb\u505aSpple\u7684\u86cb\u767d\u9644\u7740\u5e76\u4fb5\u5165\u4f53\u5185\u547c\u5438\u9053\u7ec6\u80de\u3002\u9632\u6b62\u9489\u5b50\u9644\u7740\u5728\u7ec6\u80de\u4e0a\u7684\u6297\u4f53\u53ef\u4ee5\u4e2d\u548c\u75c5\u6bd2\u5e76\u9884\u9632\u75be\u75c5\u3002\u8bb8\u591a\u53d8\u79cd\u83b7\u5f97\u4e86\u5b83\u4eec\u7684\u5c16\u5cf0\u57fa\u56e0\u7a81\u53d8\uff0c\u4f7f\u5b83\u4eec\u80fd\u591f\u9003\u907f\u4e00\u4e9b\u9488\u5bf9\u539f\u59cb\u83cc\u682a\u4ea7\u751f\u7684\u6297\u4f53\uff0c\u4ece\u800c\u7834\u574f\u4e86\u57fa\u4e8e\u6297\u4f53\u7684\u7597\u6cd5\u7684\u6709\u6548\u6027\u3002<\/p>\n
\u4e3a\u4e86\u627e\u5230\u80fd\u5bf9\u6297\u591a\u79cd\u53d8\u4f53\u7684\u4e2d\u548c\u6297\u4f53\uff0c\u7814\u7a76\u4eba\u5458\u9996\u5148\u7528\u4e00\u79cd\u79f0\u4e3a\u53d7\u4f53\u7ed3\u5408\u57df\u7684\u68d8\u7a81\u86cb\u767d\u7684\u5173\u952e\u90e8\u5206\u514d\u75ab\u5c0f\u9f20\u3002\u7136\u540e\uff0c\u4ed6\u4eec\u63d0\u53d6\u6297\u4f53\u4ea7\u751f\u7ec6\u80de\u5e76\u4ece\u4e2d\u83b7\u5f9743\u79cd\u8bc6\u522b\u53d7\u4f53\u7ed3\u5408\u57df\u7684\u6297\u4f53\u3002<\/p>\n
\u7814\u7a76\u4eba\u5458\u901a\u8fc7\u6d4b\u91cfSARS-CoV-2\u7684\u539f\u59cb\u53d8\u79cd\u5728\u57f9\u517b\u76bf\u4e2d\u611f\u67d3\u7ec6\u80de\u7684\u7a0b\u5ea6\uff0c\u7b5b\u9009\u4e8643\u79cd\u6297\u4f53\u30029\u79cd\u6700\u6709\u6548\u7684\u4e2d\u548c\u6297\u4f53\u968f\u540e\u5728\u5c0f\u9f20\u8eab\u4e0a\u8fdb\u884c\u4e86\u6d4b\u8bd5\uff0c\u4ee5\u786e\u5b9a\u5b83\u4eec\u662f\u5426\u80fd\u591f\u4fdd\u62a4\u611f\u67d3\u539f\u59cbSARS-CoV-2\u7684\u52a8\u7269\u514d\u4e8e\u75be\u75c5\u3002\u591a\u4e2a\u6297\u4f53\u901a\u8fc7\u4e86\u8fd9\u4e24\u9879\u6d4b\u8bd5\uff0c\u5177\u6709\u4e0d\u540c\u7a0b\u5ea6\u7684\u6548\u529b\u3002<\/p>\n
\u7814\u7a76\u4eba\u5458\u9009\u62e9\u4e86\u4e24\u79cd\u6700\u80fd\u6709\u6548\u4fdd\u62a4\u5c0f\u9f20\u514d\u53d7\u75be\u75c5\u4fb5\u88ad\u7684\u6297\u4f53\uff0c\u5e76\u5bf9\u5b83\u4eec\u8fdb\u884c\u4e86\u4e00\u7cfb\u5217\u75c5\u6bd2\u53d8\u4f53\u7684\u6d4b\u8bd5\u3002\u8be5\u5c0f\u7ec4\u5305\u62ec\u75c5\u6bd2\uff0c\u68d8\u86cb\u767d\u4ee3\u8868\u6240\u6709\u56db\u4e2a\u53d8\u5f02\u6bd2\u682a\uff08\u03b1\uff0c\u03b2\uff0c\u03b3\u548c\u03b4\uff09\uff0c\u4e24\u4e2a\u53d8\u79cd\u7684\u5174\u8da3\uff08Kappa\u548cIOTA\uff09\uff0c\u4ee5\u53ca\u51e0\u4e2a\u672a\u547d\u540d\u7684\u53d8\u79cd\uff0c\u88ab\u76d1\u6d4b\u4e3a\u6f5c\u5728\u5a01\u80c1\u3002\u4e00\u79cd\u6297\u4f53\uff0cSARS2-38\uff0c\u5f88\u5bb9\u6613\u4e2d\u548c\u6240\u6709\u7684\u53d8\u5f02\u3002\u6b64\u5916\uff0cSARS2-38\u7684\u4eba\u6e90\u5316\u7248\u672c\u4fdd\u62a4\u5c0f\u9f20\u514d\u53d7\u4e24\u79cd\u53d8\u4f53\u5f15\u8d77\u7684\u75be\u75c5\uff1a\u5361\u5e15\u548c\u542b\u6709\u03b2\u53d8\u4f53\u68d8\u7a81\u86cb\u767d\u7684\u75c5\u6bd2\u3002\u7814\u7a76\u4eba\u5458\u6307\u51fa\uff0c\u8fd9\u79cd\u03b2\u53d8\u79cd\u4ee5\u5bf9\u6297\u4f53\u7684\u6297\u6027\u800c\u95fb\u540d\uff0c\u56e0\u6b64\u5b83\u5bf9SARS2-38\u7684\u6297\u6027\u5c24\u5176\u663e\u8457\u3002<\/p>\n
\u8fdb\u4e00\u6b65\u7684\u5b9e\u9a8c\u7cbe\u786e\u5b9a\u4f4d\u4e86\u6297\u4f53\u8bc6\u522b\u7684\u68d8\u7a81\u86cb\u767d\u4e0a\u7684\u7cbe\u786e\u70b9\uff0c\u5e76\u5728\u8be5\u70b9\u786e\u5b9a\u4e86\u539f\u5219\u4e0a\u53ef\u80fd\u963b\u6b62\u6297\u4f53\u5de5\u4f5c\u7684\u4e24\u4e2a\u7a81\u53d8\u3002\u7136\u800c\uff0c\u8fd9\u4e9b\u7a81\u53d8\u5728\u73b0\u5b9e\u4e16\u754c\u4e2d\u662f\u6781\u5176\u7f55\u89c1\u7684\u3002\u7814\u7a76\u4eba\u5458\u641c\u7d22\u4e86\u5c06\u8fd180\u4e07\u4e2aSARS-CoV-2\u5e8f\u5217\u7684\u6570\u636e\u5e93\uff0c\u53d1\u73b0\u5176\u4e2d\u53ea\u67090.04%\u5b58\u5728\u9003\u9038\u7a81\u53d8\u3002<\/p>\n
\u201c\u8fd9\u79cd\u6297\u4f53\u65e2\u5177\u6709\u9ad8\u5ea6\u4e2d\u548c\u6027\uff08\u610f\u5473\u7740\u5b83\u5728\u4f4e\u6d53\u5ea6\u4e0b\u5de5\u4f5c\u5f97\u5f88\u597d\uff09\uff0c\u53c8\u5177\u6709\u5e7f\u6cdb\u4e2d\u548c\u6027\uff08\u610f\u5473\u7740\u5b83\u5bf9\u6240\u6709\u53d8\u4f53\u90fd\u6709\u6548\uff09\uff0c\u201d \u540c\u65f6\u4e5f\u662f\u5206\u5b50\u5fae\u751f\u7269\u5b66\u548c\u75c5\u7406\u5b66\u4e0e\u514d\u75ab\u5b66\u6559\u6388\u7684Diamond\u8bf4\uff0c\u201c\u5bf9\u4e8e\u6297\u4f53\u6765\u8bf4\uff0c\u8fd9\u662f\u4e00\u4e2a\u4e0d\u5bfb\u5e38\u4e14\u975e\u5e38\u7406\u60f3\u7684\u7ec4\u5408\u3002\u6b64\u5916\uff0c\u5b83\u8fd8\u4e0e\u68d8\u7a81\u86cb\u767d\u4e0a\u7684\u4e00\u4e2a\u72ec\u7279\u70b9\u7ed3\u5408\uff0c\u8be5\u70b9\u4e0d\u662f\u6b63\u5728\u5f00\u53d1\u7684\u5176\u4ed6\u6297\u4f53\u7684\u9776\u70b9\u3002\u8fd9\u5bf9\u8054\u5408\u6cbb\u7597\u5f88\u597d\u3002\u6211\u4eec\u53ef\u4ee5\u5f00\u59cb\u8003\u8651\u5c06\u8fd9\u79cd\u6297\u4f53\u4e0e\u53e6\u4e00\u79cd\u7ed3\u5408\u5728\u5176\u4ed6\u5730\u65b9\u7684\u6297\u4f53\u7ed3\u5408\u8d77\u6765\uff0c\u521b\u9020\u4e00\u79cd\u75c5\u6bd2\u5f88\u96be\u62b5\u6297\u7684\u8054\u5408\u7597\u6cd5\u3002\u201d<\/p>\n
\u7814\u7a76\u4eba\u5458\u5229\u7528\u68d8\u86cb\u767d\u4e0a\u7684\u53d7\u4f53\u7ed3\u5408\u533a\u57df\uff08receptor-binding domain\uff09\u6765\u514d\u75ab\u8001\u9f20\u3002SARS-CoV-2\u662f\u5229\u7528\u68d8\u86cb\u767d\u9644\u7740\u5728\u4eba\u4f53\u547c\u5438\u9053\uff0c\u5165\u4fb5\u5230\u7ec6\u80de\u5185\u90e8\u3002<\/p>\n
\u7814\u7a76\u56e2\u961f\u63d0\u53d6\u4ea7\u751f\u6297\u4f53\u7684\u7ec6\u80de\uff0c\u5e76\u4ece\u4e2d\u83b7\u5f97\u80fd\u8bc6\u522b\u53d7\u4f53\u7ed3\u5408\u533a\u57df\u768443\u79cd\u6297\u4f53\u3002\u7814\u7a76\u4eba\u5458\u900f\u8fc7\u68c0\u89c6\u8fd9\u4e9b\u6297\u4f53\u963b\u6b62SARS-CoV-2\u7684\u539f\u59cb\u75c5\u6bd2\u682a\u5728\u57f9\u517b\u76bf\u4e2d\u611f\u67d3\u7ec6\u80de\u7684\u7a0b\u5ea6\uff0c\u6765\u8fdb\u884c\u7b5b\u9009\u3002<\/p>\n
\u53e6\u5916\uff0c\u5728\u8001\u9f20\u8eab\u4e0a\u6d4b\u8bd5\u5176\u4e2d9\u79cd\u201c\u6700\u6709\u6548\u201d\u6297\u4f53\uff0c\u770b\u5b83\u4eec\u662f\u5426\u80fd\u4fdd\u62a4\u611f\u67d3SARS-CoV-2\u539f\u59cb\u75c5\u6bd2\u682a\u7684\u52a8\u7269\u3002<\/p>\n
\u7814\u7a76\u4eba\u5458\u6839\u636e\u901a\u8fc7\u6d4b\u8bd5\u591a\u4e2a\u6297\u4f53\u7684\u6548\u529b\u5404\u4e0d\u76f8\u540c\uff0c\u53d1\u73b0\u5176\u4e2d\u4e24\u4e2a\u6297\u4f53\uff0c\u80fd\u6700\u6709\u6548\u4fdd\u62a4\u8001\u9f20\uff0c\u5e76\u9488\u5bf9\u4e00\u4e9b\u53d8\u5f02\u682a\u8fdb\u884c\u6d4b\u8bd5\u3002<\/p>\n
\u8fd9\u4e9b\u53d8\u5f02\u682a\u5305\u62ec\u6240\u67094\u79cd\u9ad8\u5173\u6ce8\u53d8\u5f02\u682a\uff08Alpha\u3001Beta\u3001Gamma\u3001Delta\uff09\uff0c\u4ee5\u53ca2\u79cd\u9700\u7559\u610f\u53d8\u5f02\u682a\uff08Kappa \u3001Iota\uff09\u3002<\/p>\n
\u6700\u540e\uff0c\u7814\u7a76\u56e2\u961f\u53d1\u73b0\uff0cSARS2-38\u6297\u4f53\u201c\u53ef\u8f7b\u6613\u4e2d\u548c\u201d\u7ecf\u6d4b\u8bd5\u7684\u6240\u67096\u79cd\u53d8\u5f02\u682a\uff0c\u5c24\u5176\u662fBeta\u53d8\u5f02\u682a\u5bf9\u6b64\u6297\u4f53\u6beb\u65e0\u62b5\u6297\u529b\u3002<\/p>\n
Michael S. Diamond\u8868\u793a\uff1a\u201c\u76ee\u524d\u7684\u6297\u4f53\u53ef\u80fd\u5bf9\u4e00\u4e9b\u53d8\u5f02\u682a\u6709\u4f5c\u7528\uff0c\u4f46\u5e76\u4e0d\u662f\u6240\u6709\u53d8\u5f02\u682a\u3002\u56e0\u4e3a\u8fd9\u4e2a\u75c5\u6bd2\u53ef\u80fd\u4f1a\u7ee7\u7eed\u6f14\u5316\uff0c\u62e5\u6709\u5e7f\u6cdb\u4e2d\u548c\u4f5c\u7528\u7684\u6709\u6548\u6297\u4f53\uff0c\u9664\u4e86\u5355\u72ec\u4f7f\u7528\uff0c\u4e14\u80fd\u642d\u914d\u7ec4\u6210\u65b0\u7ec4\u5408\uff0c\u5c06\u53ef\u80fd\u9632\u6b62\u6b64\u75c5\u6bd2\u51fa\u73b0\u4efb\u4f55\u6297\u836f\u6027\u3002\u201d<\/p>\n
\u9664\u4e86Michael S. Diamond\u4e4b\u5916\uff0c\u7814\u7a76\u56e2\u961f\u4eba\u5458\u8fd8\u5305\u62ec Laura VanBlargan , Lucas J. Adams, Zhuoming Liu, Daved Fremont\u7b49\u3002<\/p>\n
\u6765\u6e90\uff1ahttps:\/\/medicine.wustl.edu\/news\/antibody-protects-against-broad-range-of-covid-19-virus-variants \u7b49\u3002<\/p>\n
\uff08\u7f8e\u56fd\u534e\u6587\u7f51 \u5723\u5730\u4e9a\u54e5\u534e\u6587\u7f51\u7f16\u53d1 USChinesePress.com SanDiegoChinesePress.com\uff09<\/p>\n<\/div>\n
<\/p>\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
\u8be5\u6821\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u4e86\u4e00\u79cd\u540d\u4e3aSARS2-38\u7684\u6297\u4f53\uff0c\u5176\u53ef\u8f7b\u6613\u4e2d\u548c\u6240\u6709\u5df2\u77e5\u76846\u79cdCOVID-19\uff082019\u51a0\u72b6\u75c5\u6bd2\u75be\u75c5\uff09\u53d8\u5f02\u682a……<\/p>\n","protected":false},"author":3,"featured_media":1488091,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[],"class_list":["post-1488090","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science_technology_education"],"_links":{"self":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/1488090","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/comments?post=1488090"}],"version-history":[{"count":0,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/1488090\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/media\/1488091"}],"wp:attachment":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/media?parent=1488090"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/categories?post=1488090"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/tags?post=1488090"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}