{"id":1496224,"date":"2025-11-10T14:25:45","date_gmt":"2025-11-10T22:25:45","guid":{"rendered":"https:\/\/www.sandiegochinesepress.com\/press\/?p=1496224"},"modified":"2026-02-23T15:53:41","modified_gmt":"2026-02-23T23:53:41","slug":"%e7%be%8e%e5%9b%bd%e5%8d%8e%e6%96%87%e7%bd%91-%e5%9c%a3%e5%9c%b0%e4%ba%9a%e5%93%a5%e5%8d%8e%e6%96%87%e7%bd%91-%e7%be%8e%e5%9b%bd%e5%8d%8e%e4%ba%ba-%e5%9c%a3%e5%9c%b0%e4%ba%9a%e5%93%a5%e5%8d%8e-21","status":"publish","type":"post","link":"https:\/\/www.sandiegochinesepress.com\/press\/%e7%be%8e%e5%9b%bd%e5%8d%8e%e6%96%87%e7%bd%91-%e5%9c%a3%e5%9c%b0%e4%ba%9a%e5%93%a5%e5%8d%8e%e6%96%87%e7%bd%91-%e7%be%8e%e5%9b%bd%e5%8d%8e%e4%ba%ba-%e5%9c%a3%e5%9c%b0%e4%ba%9a%e5%93%a5%e5%8d%8e-21\/.html","title":{"rendered":"\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5(AD)\u7684\u8349\u836f\u5929\u7136\u836f\u7269 (\u56fe\uff09"},"content":{"rendered":"<div class=\"Y3BBE\" data-sfc-cp=\"\" data-hveid=\"CAEQAA\" data-processed=\"true\">\n<p>\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5 (AD) \u7684\u5929\u7136\u8349\u836f\u836f\u7269\uff0c\u9700\u8981\u8bc6\u522b\u548c\u9a8c\u8bc1\u80fd\u591f\u9776\u5411\u8be5\u75be\u75c5\u590d\u6742\u75c5\u7406\u673a\u5236\uff08\u5305\u62ec\u708e\u75c7\u3001\u6c27\u5316\u5e94\u6fc0\u548c\u6dc0\u7c89\u6837\u86cb\u767d\u6c89\u79ef\uff09\u7684\u751f\u7269\u6d3b\u6027\u690d\u7269\u5316\u5408\u7269\u3002\u7531\u4e8e\u9700\u8981\u8fdb\u884c\u4e25\u683c\u7684\u4e34\u5e8a\u8bd5\u9a8c\u5e76\u514b\u670d\u751f\u7269\u5229\u7528\u5ea6\u4f4e\u7b49\u95ee\u9898\uff0c\u8fd9\u4e00\u8fc7\u7a0b\u6781\u5177\u6311\u6218\u6027\u3002<\/p>\n<p>\u5f53\u524d\u7814\u7a76\u73b0\u72b6 \u9488\u5bf9 AD \u7684\u5929\u7136\u4ea7\u7269\u7814\u7a76\u662f\u4e00\u4e2a\u84ec\u52c3\u53d1\u5c55\u7684\u9886\u57df\uff0c\u901a\u5e38\u501f\u9274\u4f20\u7edf\u533b\u5b66\u4f53\u7cfb\u3002\u867d\u7136\u76ee\u524d\u5c1a\u65e0\u4efb\u4f55\u8349\u836f\u83b7\u5f97 FDA \u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u6216\u9884\u9632 AD\uff0c\u4f46\u4e00\u4e9b\u690d\u7269\u6765\u6e90\u7684\u5316\u5408\u7269\u5728\u4e34\u5e8a\u524d\u7814\u7a76\u548c\u5c0f\u89c4\u6a21\u4eba\u4f53\u7814\u7a76\u4e2d\u663e\u793a\u51fa\u826f\u597d\u7684\u524d\u666f\u3002<\/p>\n<p>\u4e3b\u8981\u7814\u7a76\u9886\u57df\u5305\u62ec\uff1a<\/p>\n<p>\u4e59\u9170\u80c6\u78b1\u916f\u9176 (AChE) \u6291\u5236\uff1a\u8bb8\u591a\u6709\u524d\u666f\u7684\u8349\u836f\u542b\u6709\u80fd\u591f\u6291\u5236 AChE \u7684\u5316\u5408\u7269\u3002AChE \u662f\u4e00\u79cd\u5206\u89e3\u795e\u7ecf\u9012\u8d28\u4e59\u9170\u80c6\u78b1\u7684\u9176\uff0c\u800c\u4e59\u9170\u80c6\u78b1\u5bf9\u8bb0\u5fc6\u548c\u8ba4\u77e5\u529f\u80fd\u81f3\u5173\u91cd\u8981\u3002\u8fd9\u4e0e\u4e00\u4e9b\u7ecfFDA\u6279\u51c6\u7684\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u5904\u65b9\u836f\u7684\u4f5c\u7528\u673a\u5236\u7c7b\u4f3c\uff0c\u4f8b\u5982\u4ece\u6c34\u4ed9\u82b1\u7403\u830e\u4e2d\u63d0\u53d6\u7684\u52a0\u5170\u4ed6\u654f\u3002 \u6297\u708e\u548c\u6297\u6c27\u5316\u4f5c\u7528\uff1a\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u7684\u53d1\u75c5\u673a\u5236\u6d89\u53ca\u6162\u6027\u795e\u7ecf\u708e\u75c7\u548c\u6c27\u5316\u5e94\u6fc0\uff0c\u8bb8\u591a\u690d\u7269\u5316\u5408\u7269\u5177\u6709\u5f3a\u5927\u7684\u6297\u6c27\u5316\u548c\u6297\u708e\u7279\u6027\uff0c\u53ef\u80fd\u51cf\u8f7b\u795e\u7ecf\u5143\u635f\u4f24\u3002 \u03b2-\u6dc0\u7c89\u6837\u86cb\u767d (A\u03b2) \u548c tau \u86cb\u767d\u8c03\u8282\uff1a\u4e00\u4e9b\u5929\u7136\u5316\u5408\u7269\u4f3c\u4e4e\u53ef\u4ee5\u6291\u5236 A\u03b2 \u6591\u5757\u548c\u795e\u7ecf\u539f\u7ea4\u7ef4\u7f20\u7ed3\uff08tau \u86cb\u767d\u805a\u96c6\u4f53\uff09\u7684\u5f62\u6210\u5e76\u4fc3\u8fdb\u5176\u6e05\u9664\uff0c\u800c A\u03b2 \u6591\u5757\u548c\u795e\u7ecf\u539f\u7ea4\u7ef4\u7f20\u7ed3\u662f\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u5728\u5927\u8111\u4e2d\u7684\u5178\u578b\u6807\u5fd7\u3002 \u6709\u524d\u666f\u7684\u8349\u836f\u5019\u9009\u836f\u7269 \u76ee\u524d\u6b63\u5728\u7814\u7a76\u51e0\u79cd\u8349\u836f\u548c\u5929\u7136\u5316\u5408\u7269\u5728\u63a7\u5236\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u75c7\u72b6\u548c\u5ef6\u7f13\u75be\u75c5\u8fdb\u5c55\u65b9\u9762\u7684\u6f5c\u529b\uff1a<\/p>\n<p>\u94f6\u674f\uff1a\u56e0\u5176\u589e\u5f3a\u8840\u6db2\u6d41\u52a8\u548c\u4e3a\u5927\u8111\u63d0\u4f9b\u6297\u6c27\u5316\u4fdd\u62a4\u7684\u80fd\u529b\u800c\u5f97\u5230\u5e7f\u6cdb\u7814\u7a76\u3002\u5927\u89c4\u6a21\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4f8b\u5982\u201c\u94f6\u674f\u8bb0\u5fc6\u8bc4\u4f30\uff08GEM\uff09\u7814\u7a76\u201d\uff0c\u5728\u9884\u9632\u6216\u5ef6\u7f13\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u65b9\u9762\u53d6\u5f97\u4e86\u559c\u5fe7\u53c2\u534a\u7684\u7ed3\u679c\uff0c\u4f46\u4e00\u4e9b\u8f83\u5c0f\u7684\u7814\u7a76\u8868\u660e\uff0c\u94f6\u674f\u5728\u63a7\u5236\u73b0\u6709\u75c7\u72b6\u65b9\u9762\u6709\u4e00\u5b9a\u76ca\u5904\u3002<\/p>\n<p>\u77f3\u6749\u78b1\u7532\uff1a\u4e00\u79cd\u4ece\u77f3\u6749\uff08Huperzia serrata\uff09\u4e2d\u63d0\u53d6\u7684\u751f\u7269\u78b1\uff0c\u5c5e\u4e8e\u4e59\u9170\u80c6\u78b1\u916f\u9176\u6291\u5236\u5242\uff0c\u5e38\u4f5c\u4e3a\u975e\u5904\u65b9\u4fdd\u5065\u54c1\u4f7f\u7528\u3002\u4e00\u4e9b\u7814\u7a76\u8868\u660e\u5176\u6709\u6548\uff0c\u4f46\u7f8e\u56fd\u7684\u5927\u578b\u4e34\u5e8a\u8bd5\u9a8c\u5e76\u672a\u53d1\u73b0\u5176\u7597\u6548\u663e\u8457\u4f18\u4e8e\u5b89\u6170\u5242\u3002<\/p>\n<p>\u59dc\u9ec4\u7d20\uff1a\u59dc\u9ec4\uff08Curcuma longa\uff09\u4e2d\u7684\u6d3b\u6027\u6210\u5206\uff0c\u5177\u6709\u5f3a\u5927\u7684\u6297\u708e\u548c\u6297\u6c27\u5316\u7279\u6027\uff0c\u76ee\u524d\u6b63\u5728\u7814\u7a76\u5176\u51cf\u5c11\u6dc0\u7c89\u6837\u86cb\u767d\u6c89\u79ef\u7684\u80fd\u529b\u3002\u5176\u4e3b\u8981\u6311\u6218\u662f\u751f\u7269\u5229\u7528\u5ea6\u4f4e\uff08\u96be\u4ee5\u88ab\u4eba\u4f53\u548c\u5927\u8111\u5438\u6536\uff09\u3002<\/p>\n<p>\u5047\u9a6c\u9f7f\u82cb\uff1a\u5728\u963f\u80b2\u5420\u9640\u533b\u5b66\u4e2d\u7528\u4e8e\u589e\u5f3a\u8bb0\u5fc6\u529b\uff0c\u5176\u542b\u6709\u5047\u9a6c\u9f7f\u82cb\u82f7\uff0c\u53ef\u6539\u5584\u795e\u7ecf\u51b2\u52a8\u4f20\u9012\u5e76\u9632\u6b62\u6c27\u5316\u635f\u4f24\u3002\u5c0f\u578b\u4e34\u5e8a\u8bd5\u9a8c\u8868\u660e\uff0c\u5047\u9a6c\u9f7f\u82cb\u53ef\u4ee5\u6539\u5584\u8bb0\u5fc6\u529b\u548c\u6ce8\u610f\u529b\u3002<\/p>\n<p>\u9f20\u5c3e\u8349\uff1a\u7814\u7a76\u8868\u660e\uff0c\u9f20\u5c3e\u8349\u53ef\u901a\u8fc7\u589e\u5f3a\u80c6\u78b1\u80fd\u6d3b\u6027\uff0c\u6539\u5584\u8f7b\u5ea6\u81f3\u4e2d\u5ea6\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u8005\u7684\u8ba4\u77e5\u80fd\u529b\u5e76\u51cf\u8f7b\u5176\u8e81\u52a8\u3002<\/p>\n<p>\u85cf\u7ea2\u82b1\uff08\u756a\u7ea2\u82b1\uff09\uff1a\u85cf\u7ea2\u82b1\u63d0\u53d6\u7269\u5728\u6cbb\u7597\u8f7b\u5ea6\u81f3\u4e2d\u5ea6\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u75c7\u72b6\u65b9\u9762\uff0c\u7597\u6548\u4e0e\u4f20\u7edf\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u836f\u7269\u591a\u5948\u54cc\u9f50\u76f8\u5f53\uff0c\u4e14\u5728\u4e00\u4e9b\u7814\u7a76\u4e2d\u526f\u4f5c\u7528\u66f4\u5c11\u3002<\/p>\n<p>\u5f00\u53d1\u836f\u7528\u7ea7\u8349\u836f\u9762\u4e34\u8bf8\u591a\u6311\u6218\uff1a \u6807\u51c6\u5316\uff1a\u8349\u836f\u63d0\u53d6\u7269\u7684\u5316\u5b66\u6210\u5206\u5929\u7136\u5b58\u5728\u5dee\u5f02\uff0c\u96be\u4ee5\u5b9e\u73b0\u6807\u51c6\u5316\u5242\u91cf\u548c\u7a33\u5b9a\u7684\u4ea7\u54c1\u8d28\u91cf\u3002 \u751f\u7269\u5229\u7528\u5ea6\uff1a\u8bb8\u591a\u690d\u7269\u6765\u6e90\u7684\u5316\u5408\u7269\u96be\u4ee5\u7a7f\u8fc7\u8840\u8111\u5c4f\u969c\uff08BBB\uff09\u8fbe\u5230\u8111\u5185\u6cbb\u7597\u6d53\u5ea6\u3002<\/p>\n<p>\u4e34\u5e8a\u9a8c\u8bc1\uff1a\u9700\u8981\u8fdb\u884c\u4e25\u683c\u3001\u5927\u89c4\u6a21\u548c\u957f\u671f\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u6ee1\u8db3\u76d1\u7ba1\u8981\u6c42\uff08\u4f8b\u5982\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40 (FDA) \u7684\u8981\u6c42\uff09\uff0c\u4ece\u800c\u786e\u8ba4\u5176\u7597\u6548\u548c\u5b89\u5168\u6027\u3002<\/p>\n<p>\u836f\u7269\u76f8\u4e92\u4f5c\u7528\uff1a\u8349\u836f\u8865\u5145\u5242\u53ef\u80fd\u4e0e\u5904\u65b9\u836f\u53d1\u751f\u76f8\u4e92\u4f5c\u7528\uff0c\u8fd9\u7ed9\u901a\u5e38\u670d\u7528\u591a\u79cd\u836f\u7269\u7684\u60a3\u8005\u5e26\u6765\u5b89\u5168\u9690\u60a3\u3002 \u7814\u7a76\u4eba\u5458\u6b63\u5728\u81f4\u529b\u4e8e\u5f00\u53d1\u5148\u8fdb\u7684\u9012\u9001\u65b9\u6cd5\uff0c\u4f8b\u5982\u57fa\u4e8e\u7eb3\u7c73\u6280\u672f\u7684\u8f7d\u4f53\uff0c\u4ee5\u63d0\u9ad8\u5929\u7136\u5316\u5408\u7269\u7684\u751f\u7269\u5229\u7528\u5ea6\u5e76\u5b9e\u73b0\u5176\u5411\u5927\u8111\u7684\u9776\u5411\u9012\u9001\u3002\u5305\u62ec\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u534f\u4f1a\u5728\u5185\u7684\u79d1\u5b66\u754c\u666e\u904d\u8ba4\u4e3a\uff0c\u8fd8\u9700\u8981\u5f00\u5c55\u66f4\u591a\u7814\u7a76\uff0c\u60a3\u8005\u5728\u4f7f\u7528\u4efb\u4f55\u8865\u5145\u5242\u4e4b\u524d\u90fd\u5e94\u54a8\u8be2\u533b\u751f\u3002<\/p>\n<p>Research into natural products for AD is a growing field, often drawing on traditional medicine systems. While no herbal drugs are currently approved by the <span data-sfc-cp=\"\" data-wiz-uids=\"JTO2Qe_o\" data-processed=\"true\">FDA<\/span>\u00a0for the treatment or prevention of AD, several plant-derived compounds show promise in preclinical and small-scale human studies.<span data-animation-atomic=\"\" data-wiz-attrbind=\"class=JTO2Qe_p\/TKHnVd\" data-processed=\"true\"><span aria-hidden=\"true\" data-processed=\"true\">\u00a0<\/span><\/span><\/p>\n<p>Key areas of research focus on:<\/p>\n<p><strong data-processed=\"true\">Acetylcholinesterase (AChE) inhibition:<\/strong>\u00a0Many promising herbs contain compounds that inhibit AChE, an enzyme that breaks down the neurotransmitter acetylcholine, which is crucial for memory and cognitive function. This is similar to the mechanism of action of some FDA-approved prescription drugs for AD, such as galantamine, which is derived from the daffodil bulb plant.<\/p>\n<ul data-processed=\"true\">\n<li data-hveid=\"CAUQAQ\" data-processed=\"true\"><span data-sfc-cp=\"\" data-processed=\"true\"><strong data-processed=\"true\">Anti-inflammatory and antioxidant effects:<\/strong>\u00a0AD pathogenesis involves chronic neuroinflammation and oxidative stress, and many plant compounds possess potent antioxidant and anti-inflammatory properties that may mitigate neuronal damage.<\/span><\/li>\n<li data-hveid=\"CAUQAg\" data-processed=\"true\"><span data-sfc-cp=\"\" data-processed=\"true\"><strong data-processed=\"true\">Amyloid-beta (A\u03b2) and tau protein modulation:<\/strong>\u00a0Some natural compounds appear to inhibit the formation and promote the clearance of A\u03b2 plaques and neurofibrillary tangles (tau protein aggregates), the characteristic hallmarks of AD in the brain.<\/span><span data-wiz-uids=\"JTO2Qe_1b,JTO2Qe_1c\" data-processed=\"true\"><span aria-hidden=\"true\" data-processed=\"true\">\u00a0<\/span><\/span><\/li>\n<\/ul>\n<p>Promising Herbal Candidates<\/p>\n<p>Several herbs and natural compounds are being investigated for their potential in managing AD symptoms and progression:<span data-animation-atomic=\"\" data-wiz-attrbind=\"class=JTO2Qe_1o\/TKHnVd\" data-processed=\"true\"><span aria-hidden=\"true\" data-processed=\"true\">\u00a0<\/span><\/span><\/p>\n<ul data-processed=\"true\">\n<li data-hveid=\"CAgQAA\" data-processed=\"true\"><span data-sfc-cp=\"\" data-processed=\"true\"><strong data-processed=\"true\">Ginkgo biloba:<\/strong> Extensively studied for its ability to enhance blood flow and provide antioxidant protection to the brain. Large-scale clinical trials, such as the &#8221; Ginkgo Evaluation of Memory (GEM) &#8221; Study, have yielded mixed results regarding its efficacy in preventing or delaying AD, but some smaller studies suggest a modest benefit in managing existing symptoms.<\/span><\/li>\n<li data-hveid=\"CAgQAg\" data-processed=\"true\"><span data-sfc-cp=\"\" data-processed=\"true\"><strong data-processed=\"true\">Huperzine A:<\/strong>\u00a0An alkaloid derived from the Chinese club moss (<em data-processed=\"true\">Huperzia serrata<\/em>), it is an AChE inhibitor and is used as an over-the-counter supplement. It has demonstrated effectiveness in some studies, although large U.S. clinical trials have found no significant benefit over a placebo.<\/span><\/li>\n<li data-hveid=\"CAgQAw\" data-processed=\"true\"><span data-sfc-cp=\"\" data-processed=\"true\"><strong data-processed=\"true\">Curcumin:<\/strong>\u00a0The active compound in turmeric (<em data-processed=\"true\">Curcuma longa<\/em>), it has potent anti-inflammatory and antioxidant properties and is being explored for its ability to reduce amyloid accumulation. Its primary challenge is low bioavailability (poor absorption into the body and brain).<\/span><\/li>\n<li data-hveid=\"CAgQBA\" data-processed=\"true\"><span data-sfc-cp=\"\" data-processed=\"true\"><strong data-processed=\"true\">Bacopa monnieri:<\/strong>\u00a0Used in Ayurvedic medicine for memory enhancement, it contains bacosides that improve nerve impulse transmission and protect against oxidative damage. Small clinical trials suggest improvements in memory and attention.<\/span><\/li>\n<li data-hveid=\"CAgQBQ\" data-processed=\"true\"><span data-sfc-cp=\"\" data-processed=\"true\"><strong data-processed=\"true\">Salvia officinalis (Sage):<\/strong>\u00a0Studies have shown that sage can improve cognitive performance and reduce agitation in patients with mild-to-moderate AD by enhancing cholinergic activity.<\/span><\/li>\n<li data-hveid=\"CAgQBg\" data-processed=\"true\"><span data-sfc-cp=\"\" data-processed=\"true\"><strong data-processed=\"true\">Saffron (<\/strong><em data-processed=\"true\"><strong>Crocus sativus<\/strong><\/em><strong>):<\/strong> Saffron extract has shown comparable efficacy to the conventional AD drug donepezil in treating mild-to-moderate AD symptoms, with fewer side effects in some studies.<\/span><\/li>\n<\/ul>\n<p>Challenges in Development<\/p>\n<p>Developing a pharmaceutical-grade herbal drug involves significant hurdles:<span data-animation-atomic=\"\" data-wiz-attrbind=\"class=JTO2Qe_2w\/TKHnVd\" data-processed=\"true\"><span aria-hidden=\"true\" data-processed=\"true\">\u00a0<\/span><\/span><\/p>\n<ul>\n<li data-hveid=\"CAsQAA\" data-processed=\"true\"><span data-sfc-cp=\"\" data-processed=\"true\"><strong data-processed=\"true\">Standardization:<\/strong>\u00a0Herbal extracts naturally vary in chemical composition, making standardized dosing and consistent product quality difficult to achieve.<\/span><\/li>\n<li data-hveid=\"CAsQAQ\" data-processed=\"true\"><span data-sfc-cp=\"\" data-processed=\"true\"><strong data-processed=\"true\">Bioavailability:<\/strong>\u00a0Many plant-derived compounds face challenges crossing the blood-brain barrier (BBB) to reach therapeutic concentrations in the brain.<\/span><\/li>\n<li data-hveid=\"CAsQAg\" data-processed=\"true\"><span data-sfc-cp=\"\" data-processed=\"true\"><strong data-processed=\"true\">Clinical Validation:<\/strong>\u00a0Rigorous, large-scale, and long-term clinical trials are needed to meet regulatory requirements (like those of the\u00a0FDA) to confirm efficacy and safety.<\/span><\/li>\n<li data-hveid=\"CAsQAw\" data-processed=\"true\"><span data-sfc-cp=\"\" data-processed=\"true\"><strong data-processed=\"true\">Drug Interactions:<\/strong>\u00a0Herbal supplements can interact with prescription medications, raising safety concerns for patients often on multiple drugs.<\/span><span data-wiz-uids=\"JTO2Qe_3e,JTO2Qe_3f\" data-processed=\"true\"><span aria-hidden=\"true\" data-processed=\"true\">\u00a0<\/span><\/span><\/li>\n<li data-hveid=\"CAsQAw\" data-processed=\"true\">Researchers are working on advanced delivery methods, such as <strong data-processed=\"true\">nanotechnology-based carriers<\/strong>, to enhance the bioavailability and targeted delivery of natural compounds to the brain. The general consensus in the scientific community, including the\u00a0<span data-sfc-cp=\"\" data-processed=\"true\">Alzheimer&#8217;s Association<\/span>, is that more research is needed, and patients should consult a physician before using any supplements.<\/li>\n<\/ul>\n<p>(UC Chinese Press, San Diego Chinese Press, Report by Ranxin Shi, Xiuli Zhao, Yuhan Shi, Editor: Fei Lu)<\/p>\n<\/div>\n<p>&#8212;&#8211;<\/p>\n<p>\u6839\u636e\u7f8e\u56fd\u836f\u5b66\u9662\u534f\u4f1a\uff08AACP\uff09\u6700\u8fd1\u516c\u5e03\u7684\u6570\u636e\uff0c\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u65af\u5361\u683c\u65af\u836f\u5b66\u9662\u548c\u836f\u7269\u79d1\u5b66\u5b66\u9662(\uff08Skaggs School of Pharmacy and Pharmaceutical Sciences\uff0c\u7b80\u79f0UC San Diego SSPPS\uff09\u5728\u5168\u56fd\u7814\u7a76\u7ecf\u8d39\u6392\u540d\u4e2d\u8f83\u53bb\u5e74\u4e0a\u5347\u4e09\u4f4d\uff0c\u4f4d\u5217\u7b2c\u56db\u3002<\/p>\n<p>\u57282023-2024\u8d22\u5e74\u91cc\uff0cUC San Diego SSPPS \u4ece\u5305\u62ec\u7f8e\u56fd\u56fd\u5bb6\u513f\u7ae5\u5065\u5eb7\u4e0e\u4eba\u7c7b\u53d1\u80b2\u7814\u7a76\u6240\u3001\u7f8e\u56fd\u56fd\u5bb6\u8001\u9f84\u7814\u7a76\u6240\u548c\u7f8e\u56fd\u56fd\u5bb6\u5fc3\u80ba\u8840\u6db2\u7814\u7a76\u6240\u7b49\u673a\u6784\u83b7\u5f97\u4e86\u7ea63300\u4e07\u7f8e\u5143\u7684\u7ade\u4e89\u6027\u79d1\u7814\u7ecf\u8d39\u3002<\/p>\n<p>\u201c\u5728\u5982\u4eca\u7684\u8054\u90a6\u8d44\u52a9\u7ade\u4e89\u6fc0\u70c8\u7684\u73af\u5883\u4e0b\uff0c\u6bcf\u4e00\u5206\u94b1\u90fd\u6765\u4e4b\u4e0d\u6613\u2014\u2014\u7136\u800c\uff0c\u6211\u4eec\u7684\u6559\u804c\u5458\u5de5\u4f9d\u7136\u4fdd\u6301\u7740\u6700\u9ad8\u6c34\u5e73\u7684\u7ade\u4e89\u529b\uff0c\u201d\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u533b\u5b66\u9662\u4e34\u5e8a\u836f\u5b66\u548c\u513f\u79d1\u5b66\u6559\u6388\u3001\u65af\u5361\u683c\u65af\u836f\u5b66\u9662\u9662\u957f\u517c\u836f\u5b66\u535a\u58eb\u3001\u5e94\u7528\u79d1\u5b66\u7855\u58eb\u00a0Brookie Best\u8868\u793a\u3002\u201c\u6211\u4eec\u8fd9\u91cc\u5f00\u5c55\u7684\u6770\u51fa\u79d1\u7814\u5de5\u4f5c\u6b63\u5728\u5bf9\u513f\u7ae5\u5065\u5eb7\u3001\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u3001\u5fc3\u529b\u8870\u7aed\u3001\u5fae\u751f\u7269\u7ec4\u7b49\u9886\u57df\u4ea7\u751f\u5207\u5b9e\u7684\u5f71\u54cd\u3002\u4f46\u6211\u4eec\u4e0d\u80fd\u5c06\u8fd9\u79cd\u652f\u6301\u89c6\u4e3a\u7406\u6240\u5f53\u7136\uff0c\u5982\u679c\u6ca1\u6709\u8054\u90a6\u5c42\u9762\u7684\u6301\u7eed\u6295\u5165\uff0c\u50cf\u8fd9\u6837\u5177\u6709\u53d8\u9769\u610f\u4e49\u7684\u7814\u7a76\u5c06\u9762\u4e34\u98ce\u9669\u3002\u6211\u8981\u795d\u8d3a\u6211\u4eec\u89c4\u6a21\u867d\u5c0f\u4f46\u6210\u679c\u4e30\u7855\u7684\u6559\u804c\u5458\u5de5\uff0c\u4ed6\u4eec\u83b7\u5f97\u4e86\u8fd9\u4e9b\u5956\u9879\uff0c\u4f7f\u6211\u4eec\u5728\u836f\u5b66\u7814\u7a76\u9886\u57df\u8dfb\u8eab\u5168\u56fd\u9886\u5148\u884c\u5217\u3002\u201d<\/p>\n<p>\u7f8e\u56fd\u836f\u5b66\u9662\u534f\u4f1a (AACP) \u6bcf\u5e74\u53d1\u5e03\u7684\u8fd9\u4efd\u62a5\u544a\u6c47\u603b\u4e86\u7f8e\u56fd\u5404\u836f\u5b66\u9662\u83b7\u5f97\u7684\u6821\u5916\u79d1\u7814\u7ecf\u8d39\u603b\u989d\u3002\u6392\u540d\u4f9d\u636e\u516c\u5171\u6570\u636e\u5e93\uff0c\u4f8b\u5982\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662 (NIH) \u7684 RePORT \u6570\u636e\u5e93\uff0c\u5e76\u901a\u8fc7\u4e0e\u5404\u9662\u6821\u5408\u4f5c\u8fdb\u884c\u6838\u5b9e\uff0c\u4ee5\u786e\u4fdd\u6570\u636e\u7684\u51c6\u786e\u6027\u3002<\/p>\n<p>\u201c\u6211\u4eec\u7684\u7814\u7a76\u8303\u56f4\u975e\u5e38\u5e7f\u6cdb\uff0c\u201d\u65af\u514b\u91cc\u666e\u65af\u836f\u5b66\u9662\u548c\u836f\u5b66\u79d1\u5b66\u5b66\u9662\u8d1f\u8d23\u7814\u7a76\u4e0e\u521b\u65b0\u7684\u526f\u9662\u957f\u3001\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u533b\u5b66\u9662\u513f\u79d1\u5b66\u6559\u6388\u00a0Elizabeth Winzeler\u535a\u58eb\u8bf4\uff0c\u201c\u8fd9\u4e9b\u8d44\u52a9\u4e0d\u4ec5\u662f\u5bf9\u6211\u4eec\u79d1\u7814\u8d28\u91cf\u7684\u8ba4\u53ef\uff0c\u4e5f\u662f\u5bf9\u6211\u4eec\u6559\u804c\u5458\u5de5\u521b\u9020\u529b\u548c\u51b3\u5fc3\u7684\u80af\u5b9a\u3002\u6211\u4e3a\u4ed6\u4eec\u7684\u5de5\u4f5c\u83b7\u5f97\u5168\u56fd\u8ba4\u53ef\u800c\u611f\u5230\u81ea\u8c6a\u3002\u201d<\/p>\n<h3>\u63a8\u52a8\u836f\u5b66\u9662\u79d1\u7814\u5b9e\u529b\u7684\u4e3b\u8981\u8d44\u52a9\u9879\u76ee<\/h3>\n<h4>\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u7814\u7a76\u6bcd\u4e73\u5582\u517b\u671f\u95f4\u6297\u751f\u7d20\u7684\u4f20\u64ad<\/h4>\n<p>\u836f\u5b66\u535a\u58ebShirley Tsunoda\u662f\u4e34\u5e8a\u836f\u5b66\u6559\u6388\u517c\u836f\u5b66\u6559\u80b2\u526f\u9662\u957f\uff0c\u4e5f\u662f\u5c24\u5c3c\u65af\u00b7\u80af\u5c3c\u8fea\u00b7\u65bd\u83b1\u4f5b\u56fd\u5bb6\u513f\u7ae5\u5065\u5eb7\u4e0e\u4eba\u7c7b\u53d1\u80b2\u7814\u7a76\u6240\u4e00\u9879\u8d44\u52a9\u9879\u76ee\u7684\u9996\u5e2d\u7814\u7a76\u5458\u4e4b\u4e00\u3002\u8be5\u9879\u76ee\u65e8\u5728\u652f\u6301\u6bcd\u5a74\u7cbe\u51c6\u836f\u7406\u5b66\u5353\u8d8a\u4e2d\u5fc3\uff0c\u89d2\u7530\u535a\u58eb\u53ca\u5176\u56e2\u961f\u5728\u8be5\u4e2d\u5fc3\u9886\u5bfc\u5f00\u5c55\u7814\u7a76\uff0c\u4ee5\u786e\u5b9a\u6bcd\u4e73\u5582\u517b\u671f\u95f4\u670d\u7528\u6297\u751f\u7d20\u662f\u5426\u4f1a\u6539\u53d8\u5a74\u513f\u7684\u5fae\u751f\u7269\u7fa4\u3002\u8fd9\u4e2a\u95ee\u9898\u5bf9\u513f\u7ae5\u7684\u957f\u671f\u5065\u5eb7\u5177\u6709\u91cd\u5927\u610f\u4e49\u3002<\/p>\n<h4>\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u7814\u53d1\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u53ca\u76f8\u5173\u75be\u75c5\u7684\u65b0\u836f<\/h4>\n<p>\u836f\u5b66\u6559\u6388Conor Caffrey\u535a\u58eb\u662f\u7f8e\u56fd\u56fd\u5bb6\u8001\u9f84\u7814\u7a76\u6240\u8d44\u52a9\u7684\u4e00\u9879\u65e8\u5728\u5f00\u53d1\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u548c\u5176\u4ed6tau\u86cb\u767d\u76f8\u5173\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u65b0\u7597\u6cd5\u7684\u9879\u76ee\u8d1f\u8d23\u4eba\u3002\u8be5\u9879\u76ee\u8d1f\u8d23\u4eba\u3001\u836f\u5b66\u6559\u6388Carlo Bellatore\u535a\u58eb\u4e0d\u5e78\u53bb\u4e16\u540e\uff0cCaffrey\u535a\u58eb\u53ca\u5176\u56e2\u961f\u6b63\u7ee7\u7eed\u63a8\u8fdb\u8fd9\u9879\u7814\u7a76\uff0c\u63a2\u7d22\u4e00\u79cd\u540d\u4e3aCNDR-51997\u7684\u65b0\u578b\u5316\u5408\u7269\uff0c\u8be5\u5316\u5408\u7269\u80fd\u591f\u7a33\u5b9a\u5927\u8111\u7684\u5fae\u7ba1\u7cfb\u7edf\u2014\u2014\u5fae\u7ba1\u7cfb\u7edf\u662f\u7ef4\u6301\u795e\u7ecf\u5143\u5065\u5eb7\u529f\u80fd\u7684\u5173\u952e\u7ed3\u6784\u3002\u5728\u8054\u90a6\u653f\u5e9c\u7684\u652f\u6301\u4e0b\uff0c\u8be5\u56e2\u961f\u6b63\u81f4\u529b\u4e8e\u63a8\u8fdb\u8be5\u5316\u5408\u7269\u8fdb\u5165\u4eba\u4f53\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u3002<\/p>\n<h4>\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u5fc3\u808c\u635f\u4f24\u540e\u7684\u518d\u751f<\/h4>\n<p>\u836f\u5b66\u6559\u6388\u3001\u535a\u58ebSylvia Evans\u662f\u8fd9\u9879\u7531\u7f8e\u56fd\u56fd\u5bb6\u5fc3\u80ba\u8840\u6db2\u7814\u7a76\u6240\u8d44\u52a9\u7684\u9879\u76ee\u7684\u8d1f\u8d23\u4eba\uff0c\u8be5\u9879\u76ee\u4e13\u6ce8\u4e8e\u635f\u4f24\u540e\u5fc3\u808c\u7684\u518d\u751f\u3002\u4e0e\u9c7c\u7c7b\u6216\u4e24\u6816\u52a8\u7269\u4e0d\u540c\uff0c\u4eba\u7c7b\u5fc3\u810f\u65e0\u6cd5\u81ea\u7136\u66ff\u6362\u4e22\u5931\u7684\u808c\u8089\u7ec6\u80de\uff0c\u8fd9\u4e5f\u662f\u5fc3\u529b\u8870\u7aed\u4ecd\u7136\u662f\u5168\u7403\u9996\u8981\u6b7b\u56e0\u7684\u539f\u56e0\u3002\u57c3\u6587\u65af\u7684\u7814\u7a76\u65e8\u5728\u627e\u51fa\u963b\u6b62\u4eba\u7c7b\u5fc3\u808c\u7ec6\u80de\u5206\u88c2\u7684\u9057\u4f20\u548c\u4ee3\u8c22\u201c\u969c\u788d\u201d\uff0c\u5e76\u8bbe\u8ba1\u514b\u670d\u8fd9\u4e9b\u969c\u788d\u7684\u7b56\u7565\u3002\u5176\u957f\u671f\u76ee\u6807\u662f\u4e3a\u518d\u751f\u7597\u6cd5\u94fa\u5e73\u9053\u8def\uff0c\u4f7f\u53d7\u635f\u7684\u5fc3\u810f\u6709\u671d\u4e00\u65e5\u80fd\u591f\u81ea\u6211\u4fee\u590d\u3002<\/p>\n<h4>\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u6784\u5efa\u5168\u7403\u6700\u5927\u7684\u5fae\u751f\u7269\u7ec4\u5316\u5b66\u5e93<\/h4>\n<p>\u836f\u5b66\u6559\u6388\u3001\u535a\u58ebPieter Dorrenstein\u83b7\u5f97\u4e86\u7f8e\u56fd\u56fd\u5bb6\u7cd6\u5c3f\u75c5\u3001\u6d88\u5316\u548c\u80be\u810f\u75be\u75c5\u7814\u7a76\u6240\u7684\u8d44\u52a9\uff0c\u7528\u4e8e\u6784\u5efa\u6709\u53f2\u4ee5\u6765\u89c4\u6a21\u6700\u5927\u7684\u5fae\u751f\u7269\u7ec4\u884d\u751f\u5316\u5b66\u7269\u8d28\u53c2\u8003\u5e93\u2014\u2014\u6700\u591a\u53ef\u5305\u542b\u4e94\u767e\u4e07\u4e2a\u5206\u5b50\u3002\u6211\u4eec\u80a0\u9053\u4e2d\u7684\u5fae\u751f\u7269\u4f1a\u4ea7\u751f\u65e0\u6570\u5f71\u54cd\u4eba\u7c7b\u5065\u5eb7\u7684\u5316\u5b66\u7269\u8d28\uff0c\u4f46\u5176\u4e2d\u5927\u591a\u6570\u5c1a\u672a\u88ab\u53d1\u73b0\u3002\u591a\u4f26\u65af\u5766\u7684\u56e2\u961f\u5c06\u91c7\u7528\u4e00\u79cd\u521b\u65b0\u7684\u201c\u53cd\u5411\u4ee3\u8c22\u7ec4\u5b66\u201d\u65b9\u6cd5\uff0c\u5c06\u8fd9\u4e9b\u5316\u5b66\u7269\u8d28\u4e0e\u98df\u7269\u3001\u75be\u75c5\u548c\u5065\u5eb7\u7ed3\u679c\u8054\u7cfb\u8d77\u6765\u3002\u76ee\u524d\uff0c\u8be5\u56e2\u961f\u5df2\u7ecf\u53d1\u73b0\u4e86\u4e0e\u514b\u7f57\u6069\u75c5\u76f8\u5173\u7684\u65b0\u7684\u80c6\u6c41\u9178\u5206\u5b50\u3002\u7531\u6b64\u5efa\u7acb\u7684\u516c\u5171\u6570\u636e\u5e93\u5c06\u52a0\u901f\u7cbe\u51c6\u8425\u517b\u3001\u8bca\u65ad\u548c\u65b0\u7597\u6cd5\u7684\u7814\u7a76\u3002<\/p>\n<p>\u63d0\u4f9b3300\u4e07\u7f8e\u5143\u7ade\u4e89\u6027\u7814\u7a76\u5956\u52b1\u7684\u8d44\u52a9\u673a\u6784\u5305\u62ec\u7f8e\u56fd\u56fd\u7acb\u513f\u7ae5\u5065\u5eb7\u4e0e\u4eba\u7c7b\u53d1\u5c55\u7814\u7a76\u6240\uff08National Institute of Child Health and Human Development\uff09\u3001\u56fd\u5bb6\u8001\u9f84\u5316\u7814\u7a76\u6240\uff08National Institute on Aging\uff09\u548c\u56fd\u5bb6\u5fc3\u80ba\u8840\u6db2\u7814\u7a76\u6240\uff08National Heart, Lung, and Blood Institute\uff09\u7b49\u201c\u5927\u4f6c\u201d\u673a\u6784\u3002<\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\">According to recent data released by the Association of American Colleges of Pharmacy (AACP), the Skaggs School of Pharmacy and Pharmaceutical Sciences (UC San Diego SSPPS) at the University of California, San Diego, rose three places to rank fourth in national research funding rankings compared to last year.<\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\">In fiscal year 2023-2024, UC San Diego SSPPS received approximately $33 million in competitive research funding from institutions including the National Institute of Child Health and Human Development, the National Institute on Aging, and the National Heart, Lung, and Blood Institute.<\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\">\u201cIn today\u2019s highly competitive federal funding environment, every penny is hard-earned\u2014yet our faculty remains highly competitive,\u201d said Brookie Best, Professor of Clinical Pharmacy and Pediatrics at the University of California, San Diego School of Medicine, Dean of the Skaggs School of Pharmacy, MD, PhD, and Master of Applied Science. \u201cThe outstanding research we are conducting here is having a real impact on areas such as children\u2019s health, neurodegenerative diseases, heart failure, and the microbiome. But we cannot take this support for granted; without continued federal investment, transformative research like this would be at risk. I congratulate our small but accomplished faculty who have received these awards, placing us among the nation\u2019s leaders in pharmaceutical research.\u201d<\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\">This annual report, published by the Association of American Colleges of Pharmacy (AACP), summarizes the total amount of external research funding received by pharmacy schools across the United States. The rankings are based on public databases, such as the National Institutes of Health&#8217;s (NIH) RePORT database, and are verified in collaboration with various institutions to ensure data accuracy.<\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\">\u201cOur research is very broad,\u201d said Dr. Elizabeth Winzeler, Associate Dean for Research and Innovation at the Scripps School of Pharmacy and the School of Pharmaceutical Sciences, and Professor of Pediatrics at the University of California, San Diego School of Medicine. \u201cThese grants are not only recognition of the quality of our research, but also an affirmation of the creativity and determination of our faculty. I am proud that their work has received national recognition.\u201d<\/span><\/p>\n<h3><span dir=\"auto\" style=\"vertical-align: inherit;\">Major funding projects to promote the research capabilities of the School of Pharmacy<\/span><\/h3>\n<h4><span dir=\"auto\" style=\"vertical-align: inherit;\">\u2022 Study the transmission of antibiotics during breastfeeding<\/span><\/h4>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\">Shirley Tsunoda, PhD, is a Professor of Clinical Pharmacy and Associate Dean of Pharmacy Education, and one of the principal investigators for a funded project at the Eunice-Kennedy-Shreff National Institute of Child Health and Human Development. This project supports the Center of Excellence in Maternal and Infant Precision Pharmacology, where Dr. Tsunoda and her team are leading research to determine whether antibiotic use during breastfeeding alters the infant&#8217;s microbiome. This question has significant implications for children&#8217;s long-term health.<\/span><\/p>\n<h4><span dir=\"auto\" style=\"vertical-align: inherit;\">\u2022 Develop new drugs for the treatment of Alzheimer&#8217;s disease and related diseases<\/span><\/h4>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\">Dr. Conor Caffrey, a professor of pharmacy, was the principal investigator of a project funded by the National Institute on Aging aimed at developing new therapies for Alzheimer&#8217;s disease and other tau protein-related neurodegenerative diseases. Following the unfortunate passing of Dr. Carlo Bellatore, the project&#8217;s principal investigator and a professor of pharmacy, Dr. Caffrey and his team are continuing their research, exploring a novel compound called CNDR-51997, which can stabilize the brain&#8217;s microtubule system\u2014a key structure for maintaining healthy neuronal function. With federal government support, the team is working to advance this compound into human clinical trials.<\/span><\/p>\n<h4><span dir=\"auto\" style=\"vertical-align: inherit;\">\u2022 Regeneration after myocardial injury<\/span><\/h4>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\">Sylvia Evans, a professor of pharmacy, is leading this project, funded by the National Heart, Lung, and Blood Institute, which focuses on the regeneration of damaged heart muscle. Unlike fish or amphibians, the human heart cannot naturally replace lost muscle cells, which is why heart failure remains the leading cause of death worldwide. Evans&#8217; research aims to identify the genetic and metabolic &#8220;barriers&#8221; that prevent human heart muscle cell division and to design strategies to overcome these barriers. Her long-term goal is to pave the way for regenerative therapies that could one day enable damaged hearts to repair themselves.<\/span><\/p>\n<h4><span dir=\"auto\" style=\"vertical-align: inherit;\">\u2022 Construct the world&#8217;s largest microbiome chemical library<\/span><\/h4>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\">Pharmacy professor Pieter Dorrenstein has received funding from the National Institute of Diabetes, Digestive and Kidney Diseases to build the largest reference library of microbiome-derived chemicals ever created\u2014containing up to five million molecules. The microbes in our gut produce countless chemicals that affect human health, but most of them remain undiscovered. Dorrenstein&#8217;s team will use an innovative &#8220;reverse metabolomics&#8221; approach to link these chemicals to food, disease, and health outcomes. The team has already discovered a new bile acid molecule associated with Crohn&#8217;s disease. The resulting public database will accelerate research into precision nutrition, diagnostics, and new therapies.<\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\">The funding agencies providing the $33 million competitive research awards include leading institutions such as the National Institute of Child Health and Human Development, the National Institute on Aging, and the National Heart, Lung, and Blood Institute.<\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\">(UC Chinese Press, San Diego Chinese Press, Report by Ranxin Shi, Xiuli Zhao, Yuhan Shi, Editor: Fei Lu)<\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5 (AD) \u7684\u5929\u7136\u8349\u836f\u836f\u7269\uff0c\u9700\u8981\u8bc6\u522b\u548c\u9a8c\u8bc1\u80fd\u591f\u9776\u5411\u8be5\u75be\u75c5\u590d\u6742\u75c5\u7406\u673a\u5236\uff08\u5305\u62ec\u708e\u75c7\u3001\u6c27\u5316\u5e94\u6fc0\u548c\u6dc0\u7c89\u6837\u86cb\u767d\u6c89\u79ef\uff09\u7684\u751f\u7269\u6d3b\u6027\u690d\u7269\u5316\u5408\u7269&#8230;..<\/p>\n","protected":false},"author":3,"featured_media":1496225,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":["post-1496224","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-headline"],"_links":{"self":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/1496224","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/comments?post=1496224"}],"version-history":[{"count":5,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/1496224\/revisions"}],"predecessor-version":[{"id":1496268,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/1496224\/revisions\/1496268"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/media\/1496225"}],"wp:attachment":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/media?parent=1496224"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/categories?post=1496224"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/tags?post=1496224"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}