{"id":164673,"date":"2015-07-21T11:11:41","date_gmt":"2015-07-21T18:11:41","guid":{"rendered":"http:\/\/www.sandiegochinesepress.com\/press\/?p=164673"},"modified":"2015-07-21T11:25:32","modified_gmt":"2015-07-21T18:25:32","slug":"%e5%8a%a0%e5%a4%a7%e5%9c%a3%e5%9c%b0%e4%ba%9a%e5%93%a5%e5%88%86%e6%a0%a1%e9%99%88%e7%bb%8f%e5%ae%97%e7%a0%94%e7%a9%b6%e7%bb%84%e7%99%8c%e7%97%87%e6%b2%bb%e7%96%97%e6%96%b0%e5%8f%91%e7%8e%b0%ef%bc%88","status":"publish","type":"post","link":"https:\/\/www.sandiegochinesepress.com\/press\/%e5%8a%a0%e5%a4%a7%e5%9c%a3%e5%9c%b0%e4%ba%9a%e5%93%a5%e5%88%86%e6%a0%a1%e9%99%88%e7%bb%8f%e5%ae%97%e7%a0%94%e7%a9%b6%e7%bb%84%e7%99%8c%e7%97%87%e6%b2%bb%e7%96%97%e6%96%b0%e5%8f%91%e7%8e%b0%ef%bc%88\/.html","title":{"rendered":"\u52a0\u5927\u5723\u5730\u4e9a\u54e5\u5206\u6821\u9648\u7ecf\u5b97\u7814\u7a76\u7ec4\u764c\u75c7\u6cbb\u7597\u65b0\u53d1\u73b0\uff08\u56fe\uff09"},"content":{"rendered":"

\u764c\u75c7\u80bf\u7624\u7684\u589e\u957f\u80fd\u529b\u5f80\u5f80\u5f52\u56e0\u4e8e\u764c\u75c7\u5e72\u7ec6\u80de\uff08cancer stem cell\uff09\uff0c\u764c\u7ec6\u80de\u624d\u6709\u80fd\u529b\u6210\u957f\u548c\u65e0\u9650\u5ea6\u7684\u7e41\u6b96\u3002\u8fc7\u53bb\u5bf9\u4e8e\u764c\u75c7\u5e72\u7ec6\u80de\u5982\u4f55\u4fdd\u7559\u8fd9\u79cd\u80fd\u529b\uff0c\u8ba9\u80bf\u7624\u7ec6\u80de\u5927\u91cf\u6fc0\u589e\u7684\u8fc7\u7a0b\uff0c\u4e00\u76f4\u5904\u4e8e\u672a\u77e5\u6570\u3002\u5723\u5730\u7259\u54e5\u52a0\u5dde\u5927\u5b66\uff08UCSD\uff09\u533b\u5b66\u9662\u6559\u6388\u9648\u7ecf\u5b97\uff08Clark Chen\uff09\u9886\u5bfc\u7684\u56e2\u961f\u548c\u83ab\u5c14\u65af\u764c\u75c7\u4e2d\u5fc3\uff08Moores Cancer Center\uff09\uff0c\u5171\u540c\u5408\u4f5c\u5229\u7528\u4eba\u7c7b\u80bf\u7624\u6837\u672c\u548c\u5c0f\u9f20\u6a21\u578b\u505a\u7814\u7a76\uff0c\u53d1\u73b0\u764c\u75c7\u5e72\u7ec6\u80de\u5c5e\u6027\u7531\u8868\u89c2\u9057\u4f20\u53d8\u5316 \u2014 \u5316\u5b66\u4fee\u9970\uff08chemical modifications\uff09\u7528\u6765\u63a7\u5236\u7279\u5b9a\u57fa\u56e0\u7684\u5f00\u5173\u3002<\/p>\n

\u8fd9\u9879\u9488\u5bf9\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\uff08glioblastoma\uff09\u5982\u4f55\u7ef4\u6301\u6781\u5177\u653b\u51fb\u6027\u7684\u8111\u80bf\u7624\u764c\u75c7\u5e72\u7ec6\u80de\u6240\u9700\u9176\u7684\u7814\u7a76\u7ed3\u679c\uff0c\u53d1\u8868\u4e8e\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u9662\u520a\uff08Proceedings of the National Academy of Sciences, PNAS\uff09\uff0c\u7814\u7a76\u8868\u660e\uff0c\u662f\u4e00\u79cd\u79f0\u4e3a\u300c\u8d56\u6c28\u9178\u7279\u5f02\u6027\u53bb\u7532\u57fa\u5316\u9176 1 (Lysine-Specific Demethylase 1, LSD1)\u300d\u7684\u9176\uff0c\u5173\u95ed\u4e86\u5176\u57fa\u56e0\u7684\u8baf\u53f7\u7a0b\u5f0f\u6240\u81f4\u3002\u800c\u8fd9\u79cd\u8868\u89c2\u9057\u4f20\u7684\u6d3b\u52a8\uff0c\u5c06\u6709\u52a9\u4e8e\u89e3\u91ca\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u4e3a\u4f55\u53ef\u4ee5\u62b5\u6297\u6cbb\u7597\u3002\u66f4\u91cd\u8981\u7684\u662f\uff0c\u82e5\u80fd\u5f00\u53d1\u51fa\u4fee\u6539 LSD1 \u6c34\u51c6\u7684\u836f\u7269\uff0c\u5c06\u53ef\u4ee5\u6210\u4e3a\u63d0\u4f9b\u6cbb\u7597\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u7684\u65b0\u65b9\u6cd5\u3002<\/p>\n

\"image006\"<\/p>\n

glioblastoma<\/p>\n

\u975e\u81f4\u7624\u6027\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u7ec6\u80de (\u5de6) \u53ef\u4ee5\u81ea\u53d1\u5730\u83b7\u5f97\u764c\u75c7\u5e72\u7ec6\u80de\u7684\u7279\u5fb5 (\u53f3)\u3002<\/p>\n

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\u6765\u81ea\u53f0\u6e7e\uff0c\u76ee\u524d\u5728UCSD\u533b\u5b66\u9662\u62c5\u4efb\u795e\u7ecf\u5916\u79d1\u5b66\u526f\u6559\u6388\u3001\u7814\u7a76\u548c\u5b66\u672f\u53d1\u5c55\u526f\u4e3b\u5e2d\u7684\u9648\u7ecf\u5b97\u8868\u793a\uff0c\u6b64\u9879\u7814\u7a76\u6700\u60ca\u4eba\u7684\u53d1\u73b0\u4e4b\u4e00\uff0c\u662f\u6709\u52a8\u6001\u548c\u53ef\u9006\u72b6\u6001\u4e4b\u95f4\u7684\u8f6c\u6362\u81f4\u7624\u6027\uff0c\u4ee5\u53ca\u975e\u81f4\u7624\u6027\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u4e2d\uff0c\u6240\u786e\u5b9a\u7684\u8868\u89c2\u9057\u4f20\u8c03\u63a7\u3002<\/p>\n

\u9648\u7ecf\u5b97\u7684\u79d1\u7814\u56e2\u961f\u8fdb\u4e00\u6b65\u63a2\u7d22\u53d1\u73b0\uff0c\u51b3\u5b9a\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u7ec6\u80de\u53ef\u4ee5\u4f5c\u4e3a\u764c\u75c7\u5e72\u7ec6\u80de\u65e0\u9650\u589e\u6b96\u7684\u8868\u89c2\u9057\u4f20\u56e0\u7d20\u662f LSD1\u7684\u6c34\u5e73\u3002\u5f53LSD1\u4ece DNA\u5220\u9664\u65f6\uff0c\u5373\u4f1a\u5173\u95ed\u7ef4\u6301\u80bf\u7624\u5e72\u7ec6\u80de\u6240\u9700\u7684\u7279\u6027\uff0c\u5305\u62ecMYC\u3001SOX2\u3001OLIG2\u548cPOU3F2\u7684\u57fa\u56e0\u6570\u76ee\uff0c\u79f0\u4e3a\u7532\u57fa\u57fa\u56e2\u7684\u5316\u5b66\u6807\u8bb0\u3002<\/p>\n

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\u9648\u7ecf\u5b97\u548c\u7814\u7a76\u56e2\u961f\u4e2d\u52a9\u7406\u4e13\u6849\u79d1\u5b66\u5bb6Jie Li\u7279\u522b\u6307\u51fa\uff0c\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u7684\u8868\u89c2\u9057\u4f20\u53d8\u5316\uff0c\u4f1a\u5728\u4eba\u7c7b\u53d1\u5c55\u8fc7\u7a0b\u4e2d\u53d1\u751f\u3002<\/p>\n

\u867d\u7136\u6211\u4eec\u4f53\u5185\u7684\u5927\u591a\u6570\u7ec6\u80de\u62e5\u6709\u5b8c\u5168\u76f8\u540c\u7684DNA\u5e8f\u5217\uff0c\u4f46\u662f\u8868\u89c2\u9057\u4f20\u7684\u53d8\u5316\uff0c\u4f1a\u8ba9\u809d\u7ec6\u80de\u4e0d\u540c\u4e8e\u8111\u7ec6\u80de\uff0c\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u76f8\u540c\u7684\u7a0b\u5f0f\u8bbe\u8ba1\u8fc7\u7a0b\uff0c\u4e5f\u53ef\u4ee5\u7528\u6765\u786e\u5b9a\u764c\u7ec6\u80de\u662f\u5426\u80fd\u65e0\u9650\u5236\u7684\u6210\u957f\u3002<\/p>\n

\u8fd9\u9879\u7814\u7a76\u662f\u7531\u6851\u5854\u683c\u57fa\u91d1\u4f1a\uff08Sontag Foundation\uff09\u3001\u5df4\u52d2\u65af\u97e6\u5c14\u79d1\u59c6\u57fa\u91d1\u4f1a\uff08Burroughs Wellcome Foundation\uff09\u3001 \u57fa\u6885\u5c14\u57fa\u91d1\u4f1a\uff08Kimmel Foundation\uff09\u3001 \u6843\u8389\u4e1d\u2027\u675c\u514b\u57fa\u91d1\u4f1a\uff08Doris Duke Foundation\uff09\uff0c\u4ee5\u53ca\u548c \u798f\u522b\u514b\u57fa\u91d1\u4f1a\uff08Forbeck Foundation\uff09\u5171\u540c\u8d44\u52a9\u3002<\/p>\n

UCSD\u62a5\u9053\u94fe\u63a5\uff1ahttp:\/\/health.ucsd.edu\/news\/releases\/Pages\/2015-07-06-glioblastoma-and-epigenetics.aspx<\/p>\n

\uff08Chinese American Information Technology Association \u3001\u5723\u5730\u4e9a\u54e5\u534e\u4eba\u4e2d\u5fc3\u4f9b\u7a3f \u9898\u56fe\uff1a\u5723\u5730\u7259\u54e5\u52a0\u5dde\u5927\u5b66\u795e\u7ecf\u5916\u79d1\u5b66\u526f\u6559\u6388\u9648\u7ecf\u5b97 \u6e90\u81eakpbs.org\u7f51\u7ad9\uff09<\/p>\n

Chinese American Information Technology Association<\/p>\n

** \u65b0\u95fb\u7a3f **<\/p>\n

\u8d44\u8baf\u79d1\u6280\u534f\u4f1a8\u67088\u65e5\u6d1b\u4fa8\u4e2d\u5fc3\u4e3b\u529e\u7269\u8054\u7f51\u79d1\u6280\u8bb2\u5ea7<\/p>\n

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\u7531\u7f8e\u56fd\u8d44\u8baf\u79d1\u6280\u534f\u4f1a\u4e3b\u529e\uff0c\u5357\u52a0\u5dde\u79d1\u5de5\u5b66\u4f1a\uff0c\u7ecf\u6587\u5904\u79d1\u6280\u7ec4\u534f\u529e\u7684\u7269\u8054\u7f51\u79d1\u6280\u7814\u8ba8\u4f1a\u5c06\u5e2e\u52a9\u60a8\u4e86\u89e3\u4ec0\u9ebd\u662f\u7269\u8054\u7f51\uff1f\u4ec0\u9ebd\u662f\u7269\u8054\u7f51\u7684\u5173\u952e\u79d1\u6280\uff1f\u5b83\u53c8\u4f1a\u5982\u4f55\u5f71\u54cd\u4f60\u7684\u751f\u6d3b\u548c\u5de5\u4f5c\u3002\u7814\u8ba8\u4f1a\u4ee5\u7269\u8054\u7f51\u7684\u4ea7\u54c1\u4e0e\u5e94\u7528\u5b9e\u4f8b\u8fdb\u884c\u8ba8\u8bba\u3002\u60a8\u4e5f\u5c06\u6e05\u695a\u5730\u4e86\u89e3\u7531\u7269\u8054\u7f51\u79d1\u6280\u5e26\u6765\u7684\u5546\u673a\u548c\u6311\u6218\u5728\u90a3\u88e1\u3002<\/p>\n

\u6b64\u8bb2\u5ea7\u7528\u82f1\u6587\u6559\u5b66\uff0c\u542c\u4f17\u65e0\u9700\u5177\u5907\u7535\u8111\u4e13\u4e1a\u77e5\u8bc6\u4e0e\u80cc\u666f\u3002\u540d\u989d\u6709\u9650\uff0c\u8bf7\u5927\u5bb6\u706b\u901f\u7f51\u4e0a\u62a5\u540d\u3002<\/p>\n

\u4e3b\u9898:\u7269\u8054\u7f51\u2013\u6982\u5ff5,\u79d1\u6280\u4e0e\u5e94\u7528<\/p>\n

\u4e13\u9898\u8bae\u7a0b:<\/p>\n

\u7269\u8054\u7f51\uff1a\u6982\u5ff5\u4e0e\u79d1\u6280 (\u9648\u541b\u4eea\u535a\u58eb,\u52a0\u5dde\u5dde\u5927\u5bcc\u4e50\u987f\u5206\u6821\u8ba1\u7b97\u673a\u79d1\u5b66\u7cfb\u6559\u6388)
\n\u7269\u8054\u7f51\uff1a\u4e91\u8ba1\u7b97 (\u7ae0\u534e\u535a\u58eb, \u7f8e\u56fd\u667a\u6cf0\u79d1\u6280\u516c\u53f8\u603b\u88c1)
\n\u7269\u8054\u7f51\uff1a\u8f6f\u4ef6\u5f00\u53d1\u548c\u67b6\u6784 (\u697c\u7fa4, IBM\u8d44\u6df1\u8f6f\u4ef6\u5de5\u7a0b\u5e08)
\n\u7269\u8054\u7f51\uff1a\u4ea7\u54c1\u4e0e\u5e94\u7528 (Dani Tadmori, \u8d44\u6df1\u8f6f\u4ef6\u987e\u95ee, \u7814\u7a76\u751f)<\/p>\n

\u65f6\u95f4\uff1a8\u67088\u65e5\uff0c\u661f\u671f\u516d 10:00 am\u2013 12:00 pm<\/p>\n

\u5730\u70b9 : 9443 Telstar Ave., El Monte, CA 91731 (\u6d1b\u4fa8\u4e2d\u5fc3)<\/p>\n

\u8054\u7edc\u7535\u8bdd: \u9648\u4e2d(714-655-9026\uff09\u7ae0\u534e(310-896-8059)<\/p>\n

\u7f51\u4e0a\u5728\u7ebf\u6ce8\u518c: http:\/\/www.usaita.org\/iot-seminar-registration\/<\/p>\n

\u8d44\u8baf\u79d1\u6280\u534f\u4f1a: www.usaita.org<\/p>\n","protected":false},"excerpt":{"rendered":"

\u5723\u5730\u7259\u54e5\u52a0\u5dde\u5927\u5b66\uff08UCSD\uff09\u533b\u5b66\u9662\u6559\u6388\u9648\u7ecf\u5b97\uff08Clark Chen\uff09\u9886\u5bfc\u7684\u56e2\u961f\u548c\u83ab\u5c14\u65af\u764c\u75c7\u4e2d\u5fc3\uff08Moores Cancer Center\uff09\uff0c\u5171\u540c\u5408\u4f5c\u5229\u7528\u4eba\u7c7b\u80bf\u7624\u6837\u672c\u548c\u5c0f\u9f20\u6a21\u578b\u505a\u7814\u7a76\uff0c\u53d1\u73b0\u764c\u75c7\u5e72\u7ec6\u80de\u5c5e\u6027\u7531\u8868\u89c2\u9057\u4f20\u53d8\u5316 \u2014 \u5316\u5b66\u4fee\u9970\uff08chemical modifications\uff09\u7528\u6765\u63a7\u5236\u7279\u5b9a\u57fa\u56e0\u7684\u5f00\u5173……<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[34],"class_list":["post-164673","post","type-post","status-publish","format-standard","hentry","category-headline","tag-featured-2"],"_links":{"self":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/164673","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/comments?post=164673"}],"version-history":[{"count":0,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/164673\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/media?parent=164673"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/categories?post=164673"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/tags?post=164673"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}