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\/><\/p>\n<p><strong>\u25b2<\/strong><strong>\u5f20\u950b\u6559\u6388\u662f\u5e03\u7f57\u5fb7\u7814\u7a76\u6240\u6700\u5e74\u8f7b\u7684\u8bfe\u9898\u8d1f\u8d23\u4eba<\/strong><strong>\uff08\u56fe\u7247\u6765\u6e90\uff1aMIT\uff09<\/strong><\/p>\n<p>\u5728\u90a3\u91cc\uff0c\u5f20\u950b\u6559\u6388\u663e\u793a\u51fa\u4e86\u5353\u8d8a\u7684\u773c\u5149\u3002\u201c\u4ed6\u603b\u662f\u80fd\u53d1\u73b0\u5177\u6709\u6f5c\u529b\u7684\u60f3\u6cd5\u201d\uff0c\u4ed6\u7684\u540c\u4e8b\u4eec\u5728\u4e00\u6b21\u91c7\u8bbf\u4e2d\u66fe\u8fd9\u6837\u8bf4\u9053\u3002\u81ea\u7136\uff0c\u50cfCRISPR-Cas9\u57fa\u56e0\u7f16\u8f91\u7cfb\u7edf\u8fd9\u6837\u5145\u6ee1\u53d8\u9769\u80fd\u529b\u7684\u6280\u672f\uff0c\u4e5f\u4e0d\u4f1a\u88ab\u5f20\u950b\u6559\u6388\u7684\u6167\u773c\u6240\u5ffd\u7565\u3002<\/p>\n<p>\u6700\u521d\uff0cCRISPR-Cas9\u7cfb\u7edf\u4ec5\u4ec5\u662f\u7279\u5b9a\u7ec6\u83cc\u4f53\u5185\u7528\u6765\u62b5\u5fa1\u75c5\u6bd2\u611f\u67d3\u7684\u201c\u514d\u75ab\u7cfb\u7edf\u201d\uff0c\u7136\u800c\u5305\u62ec\u5f20\u950b\u6559\u6388\u5728\u5185\uff0c\u8bb8\u591a\u79d1\u7814\u4eba\u5458\u90fd\u610f\u8bc6\u5230\uff0c\u8fd9\u4e00\u7cfb\u7edf\u6709\u671b\u7528\u4e8e\u7cbe\u786e\u3001\u5feb\u901f\u7684\u57fa\u56e0\u7f16\u8f91\u30022012\u5e74\uff0cJennifer Doudna\u6559\u6388\u4e0eEmmanuelle Charpentier\u6559\u6388\u5728\u300a\u79d1\u5b66\u300b\u6742\u5fd7\u4e0a\u53d1\u8868\u6587\u7ae0\uff0c\u786e\u8ba4CRISPR-Cas9\u7cfb\u7edf\u5728\u4f53\u5916\u5b9e\u9a8c\u4e2d\u80fd\u201c\u5b9a\u70b9\u201d\u5bf9DNA\u8fdb\u884c\u5207\u5272\u3002\u4e24\u4e2a\u6708\u540e\uff0cVirginijus Siksnys\u6559\u6388\u5728\u300aPNAS\u300b\u6742\u5fd7\u4e0a\u53d1\u8868\u4e86\u7c7b\u4f3c\u7684\u7814\u7a76\u3002\u8fd9\u4e9b\u8bba\u6587\u4e5f\u8868\u660eCRISPR-Cas9\u7cfb\u7edf\u4f5c\u4e3a\u57fa\u56e0\u7f16\u8f91\u5de5\u5177\u7684\u5de8\u5927\u6f5c\u529b\u3002<\/p>\n<p><img decoding=\"async\" src=\"http:\/\/mmbiz.qpic.cn\/mmbiz_jpg\/FcLK21Ir4gM9De4oiaTVeNuwlwzJaR3s5OCkibHKTK2dqFHrmHZq4VjELeGzNr7icjia1VyAFcgdSwT2GhHVEWiaevw\/640?wx_fmt=jpeg&amp;wxfrom=5&amp;wx_lazy=1\" data-fail=\"0\" data-s=\"300,640\" data-type=\"jpeg\" data-src=\"http:\/\/mmbiz.qpic.cn\/mmbiz_jpg\/FcLK21Ir4gM9De4oiaTVeNuwlwzJaR3s5OCkibHKTK2dqFHrmHZq4VjELeGzNr7icjia1VyAFcgdSwT2GhHVEWiaevw\/0?wx_fmt=jpeg\" data-ratio=\"0.6666666666666666\" data-w=\"405\" \/><img decoding=\"async\" src=\"data:image\/png;base64,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\" data-s=\"300,640\" data-type=\"jpeg\" data-src=\"http:\/\/mmbiz.qpic.cn\/mmbiz_jpg\/FcLK21Ir4gM9De4oiaTVeNuwlwzJaR3s5OCkibHKTK2dqFHrmHZq4VjELeGzNr7icjia1VyAFcgdSwT2GhHVEWiaevw\/0?wx_fmt=jpeg\" data-ratio=\"0.6666666666666666\" data-w=\"405\" \/><br \/>\n<strong>\u25b2<\/strong><strong>\u8bb8\u591a\u4e1a\u5185\u4eba\u58eb\u8ba4\u4e3a\uff0cDoudna\u6559\u6388\u3001Charpentier\u6559\u6388\u4e0e\u5f20\u950b\u6559\u6388\u6709\u671b\u56e0\u5728CRISPR-Cas9\u7cfb\u7edf\u4e0a\u7684\u6770\u51fa\u8d21\u732e\u800c\u83b7\u5f97\u8bfa\u8d1d\u5c14\u5956<\/strong><strong>\uff08\u56fe\u7247\u6765\u6e90\uff1aPLOS\uff09<\/strong><\/p>\n<p>\u8fd9\u79bbCRISPR-Cas9\u7cfb\u7edf\u7684\u8fdb\u4e00\u6b65\u5e94\u7528\u53ea\u5dee\u4e34\u95e8\u4e00\u811a\uff1a\u79d1\u5b66\u5bb6\u4eec\u9700\u8981\u8bc1\u5b9e\uff0c\u8fd9\u9879\u6765\u6e90\u4e8e\u7ec6\u83cc\u7684\u57fa\u56e0\u7f16\u8f91\u7cfb\u7edf\uff0c\u540c\u6837\u80fd\u5e94\u7528\u4e8e\u4eba\u4f53\u3002\u8fd9\u53ef\u662f\u4e2a\u5927\u80c6\u7684\u5047\u8bbe\u3002\u8981\u77e5\u9053\uff0c\u4e24\u8005\u7684\u57fa\u56e0\u7ec4\u590d\u6742\u7a0b\u5ea6\u6709\u7740\u4e91\u6ce5\u4e4b\u522b\u3002<\/p>\n<p>\u7136\u800c\u5f20\u950b\u6559\u6388\u4e0e\u4ed6\u7684\u56e2\u961f\u505a\u5230\u4e86\u30022013\u5e74\uff0c\u5f20\u950b\u6559\u6388\u5728\u300a\u79d1\u5b66\u300b\u6742\u5fd7\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u91cd\u78c5\u7814\u7a76\uff1a\u4ed6\u4eec<strong>\u9996\u6b21\u5728\u54fa\u4e73\u52a8\u7269\u5185<\/strong>\u5e94\u7528\u4e86CRISPR-Cas9\u7cfb\u7edf\uff0c\u5e76\u786e\u8ba4\u5b83\u80fd\u5728\u51e0\u5468\u5185\u5efa\u7acb\u8d77\u5c0f\u9f20\u7684\u75be\u75c5\u6a21\u578b\u3002\u6b64\u5916\uff0c\u5f20\u950b\u56e2\u961f\u4e5f<strong>\u9996\u6b21\u5728\u4eba\u4f53\u7ec6\u80de\u5185<\/strong>\u6210\u529f\u5730\u7528CRISPR-Cas9\u7cfb\u7edf\u5b8c\u6210\u4e86\u57fa\u56e0\u7f16\u8f91\u3002<\/p>\n<p>\u8fd9\u4e9b\u53d1\u73b0\u5e26\u6765\u4e86CRISPR-Cas9\u7cfb\u7edf\u7684\u5de8\u5927\u53d8\u9769\u3002\u5b83\u8ba9\u79d1\u5b66\u5bb6\u4eec\u80fd\u591f\u5b8c\u6210\u5148\u524d\u4e0d\u6562\u8bbe\u60f3\u7684\u5de5\u4f5c\u3002\u5982\u4eca\uff0c\u6211\u4eec\u6709\u671b\u80fd\u6e05\u9664\u6bcf\u4e00\u4e2a\u53d7\u611f\u67d3\u7ec6\u80de\u4e2d\u7684\u827e\u6ecb\u75c5\u75c5\u6bd2\uff0c\u6216\u662f\u6cbb\u7597\u9570\u5200\u72b6\u7ea2\u7ec6\u80de\u8d2b\u8840\u75c7\u7b49\u7ecf\u5178\u7684\u9057\u4f20\u75be\u75c5\u3002\u751a\u81f3\uff0c\u79d1\u5b66\u5bb6\u4eec\u5df2\u7ecf\u7545\u60f3\u5229\u7528\u5b83\u6765\u653b\u514b\u764c\u75c7\u7684\u53ef\u80fd\u3002\u6b64\u5916\uff0c\u5b83\u4e5f\u80fd\u5728\u690d\u7269\u7684\u57fa\u56e0\u7ec4\u4e2d\u5f97\u5230\u5e94\u7528\u3002\u8fd9\u80fd\u5e26\u6765\u5168\u65b0\u7684\u751f\u7269\u80fd\u6e90\uff0c\u6216\u5e26\u6765\u6027\u72b6\u66f4\u7a33\u5b9a\u7684\u4f5c\u7269\u3002<\/p>\n<p>\u4eca\u5e746\u6708\uff0cCRISPR-Cas9\u6280\u672f\u5df2\u88ab\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\uff08National Institutes of Health, NIH\uff09<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDA5NTIxNQ==&amp;mid=2649953013&amp;idx=1&amp;sn=f61d4da9ecf71606533a1abbc98397a7&amp;scene=21#wechat_redirect\" target=\"_blank\">\u6b63\u5f0f\u6279\u51c6\u7528\u4e8e\u4eba\u4f53\u57fa\u56e0\u7f16\u8f91<\/a> \u3002\u5bbe\u5dde\u5927\u5b66\u7684Carl June\u6559\u6388\u7b49\u4eba\u5e0c\u671b\u5229\u7528CRISPR-Cas9\u6280\u672f\u79fb\u9664\u764c\u75c7\u60a3\u8005T\u7ec6\u80de\u7684\u591a\u4e2a\u57fa\u56e0\uff0c\u4ece\u800c\u6fc0\u6d3bT\u7ec6\u80de\uff0c\u7528\u6765\u6cbb\u7597\u764c\u75c7\u3002\u800cNature\u4e5f\u62a5\u9053\u8bf4\u534e\u897f\u533b\u9662\u7684\u5362\u94c0\u6559\u6388\u7684\u56e2\u961f\u57288\u6708\u5f00\u5c55\u4e86<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDA5NTIxNQ==&amp;mid=2649953822&amp;idx=1&amp;sn=c89b0834a5823ebf1381611dbd87ef9a&amp;scene=21#wechat_redirect\" target=\"_blank\">\u53f2\u4e0a\u9996\u4f8bCRISPR-Cas9\u7cfb\u7edf\u5728\u4eba\u4f53\u4e2d\u7684\u5e94\u7528<\/a>\uff0c\u7528\u4e8e\u80ba\u764c\u60a3\u8005\u7684\u6cbb\u7597\u3002<\/p>\n<p>\u4e00\u4e2a\u5d2d\u65b0\u7684\u9886\u57df\u5f00\u542f\u4e86\u3002<\/p>\n<p>\u672c\u6b21\u5165\u9009\u201c\u4e0b\u4e00\u4ee3\u9886\u8896\u201d\uff0c\u6b63\u662f\u300a\u65f6\u4ee3\u5468\u520a\u300b\u5bf9\u5f20\u950b\u6559\u6388\u5728\u5982\u6b64\u5e74\u8f7b\u7684\u524d\u63d0\u4e0b\uff0c\u505a\u51fa\u5982\u6b64\u91cd\u91cf\u7ea7\u8d21\u732e\u7684\u80af\u5b9a\u3002\u6b63\u5982\u5f20\u950b\u6559\u6388\u6240\u8a00\uff0c\u65e0\u8bba\u662f\u5bf9\u4ed6\u4e2a\u4eba\uff0c\u8fd8\u662f\u5bf9\u79d1\u5b66\uff0c\u4e00\u5207\u5c31\u8fd9\u6837\u6539\u53d8\u4e86\u3002<strong>\u6211\u4eec\u6709\u4e86\u7cbe\u786e\u7f16\u8f91DNA\u7684\u80fd\u529b\uff0c\u8fd9\u5bf9\u533b\u5b66\u3001\u57fa\u7840\u751f\u7269\u7814\u7a76\u6216\u662f\u690d\u7269\u751f\u7269\u5b66\uff0c\u90fd\u6709\u7740\u91cd\u8981\u7684\u52a0\u901f\u548c\u50ac\u5316\u4f5c\u7528\u3002<\/strong><\/p>\n<p>\u6211\u4eec\u606d\u559c\u5f20\u950b\u6559\u6388\u80fd\u591f\u5165\u9009\u8be5\u699c\u5355\uff0c\u5e76\u767b\u4e0a\u300a\u65f6\u4ee3\u5468\u520a\u300b\u5c01\u9762\u3002\u4e5f\u795d\u613f\u5728\u8bf8\u591a\u79d1\u7814\u4eba\u5458\u7684\u52aa\u529b\u4e0b\uff0cCRISPR-Cas9\u7cfb\u7edf\u80fd\u591f\u7ed9\u60a3\u8005\u4eec\u5e26\u6765\u66f4\u591a\u6cbb\u7597\u7684\u9009\u62e9\uff0c\u9020\u798f\u4eba\u7c7b\u7684\u5065\u5eb7\u3002\uff08\u64b0\u7a3f\uff1a\u987e\u65b9\u4e3a\u535a\u58eb\uff09<\/p>\n<p>\u53c2\u8003\u8d44\u6599\uff1a<\/p>\n<p>[1] The Editor of Life\u2019s Building Blocks<\/p>\n<p>[2] Meet one of the world\u2019s most groundbreaking scientists. He\u2019s 34.<\/p>\n<p><img decoding=\"async\" src=\"http:\/\/mmbiz.qpic.cn\/mmbiz\/FcLK21Ir4gOMDVCh03ouIsgsdibNZesJgZMuCmVflpq00oZpuUDkcMl6ibzSMTggl6TI2fWS6QGMnOnCzIREPDDw\/0?wx_fmt=gif&amp;wxfrom=5&amp;wx_lazy=1\" data-fail=\"0\" data-type=\"gif\" data-src=\"http:\/\/mmbiz.qpic.cn\/mmbiz\/FcLK21Ir4gOMDVCh03ouIsgsdibNZesJgZMuCmVflpq00oZpuUDkcMl6ibzSMTggl6TI2fWS6QGMnOnCzIREPDDw\/0?wx_fmt=gif\" data-ratio=\"0.2\" data-w=\"600\" \/><\/p>\n<p><img decoding=\"async\" src=\"http:\/\/mmbiz.qpic.cn\/mmbiz\/FcLK21Ir4gOtwvkRqyFfcFGs7yoUJFk1QzYDRsribXGvfh0jyhbwAyUickxlmVyBoRMEQnTSQAKSGcHa2oyCAyDA\/0?wx_fmt=gif&amp;wxfrom=5&amp;wx_lazy=1\" data-fail=\"0\" data-type=\"gif\" data-src=\"http:\/\/mmbiz.qpic.cn\/mmbiz\/FcLK21Ir4gOtwvkRqyFfcFGs7yoUJFk1QzYDRsribXGvfh0jyhbwAyUickxlmVyBoRMEQnTSQAKSGcHa2oyCAyDA\/0?wx_fmt=gif\" data-ratio=\"0.2816666666666667\" data-w=\"600\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u836f\u660e\u5eb7\u5fb7\/\u62a5\u9053 \u5728\u6700\u65b0\u7684\u4e00\u671f\u300a\u65f6\u4ee3\u5468\u520a\u300b\u4e0a\uff0c\u534e\u4eba\u5b66\u8005\u5f20\u950b\u6559\u6388\u4f5c\u4e3a\u201c\u4e0b\u4e00\u4ee3\u9886\u8896\u201d\uff08Next Generation &hellip; <a href=\"https:\/\/www.sandiegochinesepress.com\/press\/%e5%bc%a0%e9%94%8b%e6%95%99%e6%8e%88%e7%99%bb%e4%b8%8a%e3%80%8a%e6%97%b6%e4%bb%a3%e5%91%a8%e5%88%8a%e3%80%8b%e5%b0%81%e9%9d%a2%ef%bc%9a%e7%bc%96%e8%be%91%e5%9f%ba%e5%9b%a0%e7%bb%84%e7%9a%84%e4%b8%8b\/.html\" class=\"more-link\">\u7ee7\u7eed\u9605\u8bfb<span class=\"screen-reader-text\">\u5f20\u950b\u6559\u6388\u767b\u4e0a\u300a\u65f6\u4ee3\u5468\u520a\u300b\u5c01\u9762\uff1a\u7f16\u8f91\u57fa\u56e0\u7ec4\u7684\u4e0b\u4e00\u4ee3\u9886\u8896<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16],"tags":[],"class_list":["post-302170","post","type-post","status-publish","format-standard","hentry","category-science_technology_education"],"_links":{"self":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/302170","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/comments?post=302170"}],"version-history":[{"count":0,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/posts\/302170\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/media?parent=302170"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/categories?post=302170"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sandiegochinesepress.com\/press\/wp-json\/wp\/v2\/tags?post=302170"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}